CD25 Blockade Depletes and Selectively Reprograms Regulatory T Cells in Concert with Immunotherapy in Cancer Patients

CD28 Costimulation Is Essential for Human T Regulatory Expansion and Function

(2014) T. N. Golovina et al.   JOURNAL OF IMMUNOLOGY

Monoclonal antibody blockade of IL-2 receptor   during lymphopenia selectively depletes regulatory T cells in mice and humans

(2011) D. A. Mitchell et al.   BLOOD

Window of opportunity for daclizumab

(2011) Kimberly S Schluns   NATURE MEDICINE

A role for interleukin-2 trans-presentation in dendritic cell–mediated T cell activation in humans, as revealed by daclizumab therapy

(2011) Simone C Wuest et al.   NATURE MEDICINE

Retinoic Acid and Rapamycin Differentially Affect and Synergistically Promote the Ex Vivo Expansion of Natural Human T Regulatory Cells

(2011) Tatiana N. Golovina et al.   PLoS One

Regulatory T Cells

(2010) Tatiana N. Golovina et al.   CANCER JOURNAL

Dendritic Cell Vaccination in Combination with Anti-CD25 Monoclonal Antibody Treatment: A Phase I/II Study in Metastatic Melanoma Patients

(2010) J. F. M. Jacobs et al.   CLINICAL CANCER RESEARCH

Development and application of a multiplexable flow cytometry-based assay to quantify cell-mediated cytolysis

(2010) Lan-Feng Cao et al.   CYTOMETRY PART A

Daclizumab in active relapsing multiple sclerosis (CHOICE study): a phase 2, randomised, double-blind, placebo-controlled, add-on trial with interferon beta

(2010) Daniel Wynn et al.   LANCET NEUROLOGY

Stability of the Regulatory T Cell Lineage in Vivo

(2010) Y. P. Rubtsov et al.   SCIENCE

Clinical Use of Anti-CD25 Antibody Daclizumab to Enhance Immune Responses to Tumor Antigen Vaccination by Targeting Regulatory T cells

(2009) Andrew J. Rech et al.   Annals of the New York Academy of Sciences

Homeostasis of peripheral FoxP3+ CD4+ regulatory T cells in patients with early and late stage breast cancer

(2009) Andrew J. Rech et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Plasticity of CD4+ FoxP3+ T cells

(2009) Xuyu Zhou et al.   CURRENT OPINION IN IMMUNOLOGY

Mechanisms of Foxp3+ T Regulatory Cell-Mediated Suppression

(2009) Ethan M. Shevach   IMMUNITY

Decrease of Foxp3+ Treg Cell Number and Acquisition of Effector Cell Phenotype during Lethal Infection

(2009) Guillaume Oldenhove et al.   IMMUNITY

Functional Delineation and Differentiation Dynamics of Human CD4+ T Cells Expressing the FoxP3 Transcription Factor

(2009) Makoto Miyara et al.   IMMUNITY

Regulatory T Cells and Immune Tolerance

(2008) Shimon Sakaguchi et al.   CELL

Anti-CD25 antibodies affect cytokine synthesis pattern of human dendritic cells and decrease their ability to prime allogeneic CD4+ T cells

(2008) K. Mnasria et al.   JOURNAL OF LEUKOCYTE BIOLOGY

The Biology of Interleukin-2

(2007) Thomas R. Malek   Annual Review of Immunology

Functional analysis of CD8+ T cell responses to the onconeural self protein cdr2 in patients with paraneoplastic cerebellar degeneration

(2007) Erica L. Carpenter et al.   JOURNAL OF NEUROIMMUNOLOGY