Inhibition of hypoxia inducible factors combined with all-trans retinoic acid treatment enhances glial transdifferentiation of neuroblastoma cells

The Role of Hypoxia Inducible Factor-1 Alpha in Bypassing Oncogene-Induced Senescence

(2014) Mehtap Kilic Eren et al.   PLoS One

Pilot trial of EZN-2968, an antisense oligonucleotide inhibitor of hypoxia-inducible factor-1 alpha (HIF-1α), in patients with refractory solid tumors

(2013) Woondong Jeong et al.   CANCER CHEMOTHERAPY AND PHARMACOLOGY

Targeting Hypoxia for Sensitization of Tumors to Radio- and Chemotherapy

(2013) Khaled Ghattass et al.   CURRENT CANCER DRUG TARGETS

Hypoxia inducible factor pathway inhibitors as anticancer therapeutics

(2013) Sarah K Burroughs et al.   Future Medicinal Chemistry

HIF-1α activation mediates resistance to anti-angiogenic therapy in neuroblastoma xenografts

(2013) Joseph Hartwich et al.   JOURNAL OF PEDIATRIC SURGERY

Neuroblastoma in older children, adolescents and young adults: A report from the International Neuroblastoma Risk Group project

(2013) Yaël P. Mossé et al.   PEDIATRIC BLOOD & CANCER

Changes in Gene Expression Profiling of Apoptotic Genes in Neuroblastoma Cell Lines upon Retinoic Acid Treatment

(2013) Jon Celay et al.   PLoS One

Exendin-4 Induces Cell Adhesion and Differentiation and Counteracts the Invasive Potential of Human Neuroblastoma Cells

(2013) Paola Luciani et al.   PLoS One

Tyrosine phosphatase inhibitors combined with retinoic acid can enhance differentiation of neuroblastoma cells and trigger ERK- and AKT-dependent, p53-independent senescence

(2012) Owen Clark et al.   CANCER LETTERS

Murine Anti-GD2 Monoclonal Antibody 3F8 Combined With Granulocyte-Macrophage Colony-Stimulating Factor and 13-Cis-Retinoic Acid in High-Risk Patients With Stage 4 Neuroblastoma in First Remission

(2012) Nai-Kong V. Cheung et al.   JOURNAL OF CLINICAL ONCOLOGY

Neuroblastoma

(2012) Andrew M. Davidoff   Seminars in Pediatric Surgery

All-trans retinoic acid induces cellular senescence via upregulation of p16, p21, and p27

(2011) Sun-Hye Park et al.   CANCER LETTERS

Multihistology, Target-Driven Pilot Trial of Oral Topotecan as an Inhibitor of Hypoxia-Inducible Factor-1  in Advanced Solid Tumors

(2011) S. Kummar et al.   CLINICAL CANCER RESEARCH

Copy number defects of G1-Cell cycle genes in neuroblastoma are frequent and correlate with high expression of E2F target genes and a poor prognosis

(2011) Jan J. Molenaar et al.   GENES CHROMOSOMES & CANCER

Neuroblastoma aggressiveness in relation to sympathetic neuronal differentiation stage

(2011) Sofie A. Mohlin et al.   SEMINARS IN CANCER BIOLOGY

Progress in treatment and risk stratification of neuroblastoma: Impact on future clinical and basic research

(2011) Ingrid Øra et al.   SEMINARS IN CANCER BIOLOGY

Effect of Hypoxia/Reoxygenation on Cell Viability and Expression and Secretion of Neurotrophic Factors (NTFs) in Primary Cultured Schwann Cells

(2010) Hao Zhu et al.   Anatomical Record-Advances in Integrative Anatomy and Evolutionary Biology

Epigenetics: The epicenter of the hypoxic response

(2010) Jenny A. Watson et al.   Epigenetics

Discovering the false discovery rate

(2010) Yoav Benjamini   JOURNAL OF THE ROYAL STATISTICAL SOCIETY SERIES B-STATISTICAL METHODOLOGY

A conceptual framework for the identification of candidate drugs and drug targets in acute promyelocytic leukemia

(2010) T T Marstrand et al.   LEUKEMIA

Anti-angiogenic SPARC peptides inhibit progression of neuroblastoma tumors

(2010) Alexandre Chlenski et al.   Molecular Cancer

Recent Advances in Neuroblastoma

(2010) John M. Maris   NEW ENGLAND JOURNAL OF MEDICINE

Comprehensive characterization of neuroblastoma cell line subtypes reveals bilineage potential similar to neural crest stem cells

(2009) Sandra Acosta et al.   BMC DEVELOPMENTAL BIOLOGY

Development of HIF-1 inhibitors for cancer therapy

(2009) Barbara Onnis et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Inhibition of oxygen sensors as a therapeutic strategy for ischaemic and inflammatory disease

(2009) Peter Fraisl et al.   NATURE REVIEWS DRUG DISCOVERY

HIF-2  maintains an undifferentiated state in neural crest-like human neuroblastoma tumor-initiating cells

(2009) A. Pietras et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

In vivo and in vitro effects of a HIF-1α inhibitor, RX-0047

(2008) Z. Gunnur Dikmen et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Topotecan inhibits vascular endothelial growth factor production and angiogenic activity induced by hypoxia in human neuroblastoma by targeting hypoxia-inducible factor-1  and -2 

(2008) M. Puppo et al.   MOLECULAR CANCER THERAPEUTICS