Type I interferon signaling contributes to the bias that Toll-like receptor 4 exhibits for signaling mediated by the adaptor protein TRIF

Dual Signaling of MyD88 and TRIF Is Critical for Maximal TLR4-Induced Dendritic Cell Maturation

(2014) H. Shen et al.   JOURNAL OF IMMUNOLOGY

TLR4 Ligands Induce IFN-  Production by Mouse Conventional Dendritic Cells and Human Monocytes after IFN-  Priming

(2014) C. Richez et al.   JOURNAL OF IMMUNOLOGY

MyD88 and TRIF synergistic interaction is required for TH1-cell polarization with a synthetic TLR4 agonist adjuvant

(2013) Mark T. Orr et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Structural basis of a unique interferon-β signaling axis mediated via the receptor IFNAR1

(2013) Nicole A de Weerd et al.   NATURE IMMUNOLOGY

TRIF Is Required for TLR4 Mediated Adjuvant Effects on T Cell Clonal Expansion

(2013) Siva K. Gandhapudi et al.   PLoS One

TRIF Licenses Caspase-11-Dependent NLRP3 Inflammasome Activation by Gram-Negative Bacteria

(2012) Vijay A.K. Rathinam et al.   CELL

Selective TRIF-Dependent Signaling by a Synthetic Toll-Like Receptor 4 Agonist

(2012) W. S. Bowen et al.   Science Signaling

CD14 Controls the LPS-Induced Endocytosis of Toll-like Receptor 4

(2011) Ivan Zanoni et al.   CELL

Mechanism of Impaired NLRP3 Inflammasome Priming by Monophosphoryl Lipid A

(2011) C. A. Embry et al.   Science Signaling

MD-2 Residues Tyrosine 42, Arginine 69, Aspartic Acid 122, and Leucine 125 Provide Species Specificity for Lipid IVA

(2010) Jianmin Meng et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Differential Induction of Innate Immune Responses by Synthetic Lipid A Derivatives

(2010) Jidnyasa Gaekwad et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Helical assembly in the MyD88–IRAK4–IRAK2 complex in TLR/IL-1R signalling

(2010) Su-Chang Lin et al.   NATURE

Selective Activation of the p38 MAPK Pathway by Synthetic Monophosphoryl Lipid A

(2009) Caglar Cekic et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The structural basis of lipopolysaccharide recognition by the TLR4–MD-2 complex

(2009) Beom Seok Park et al.   NATURE

Roles for LPS-dependent interaction and relocation of TLR4 and TRAM in TRIF-signaling

(2008) Natsuko Tanimura et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Lys63-Linked Polyubiquitination of IRAK-1 Is Required for Interleukin-1 Receptor- and Toll-Like Receptor-Mediated NF- B Activation

(2008) D. B. Conze et al.   MOLECULAR AND CELLULAR BIOLOGY

Interleukin-1 (IL-1) Induces the Lys63-Linked Polyubiquitination of IL-1 Receptor-Associated Kinase 1 To Facilitate NEMO Binding and the Activation of I B  Kinase

(2008) M. Windheim et al.   MOLECULAR AND CELLULAR BIOLOGY

TRAM couples endocytosis of Toll-like receptor 4 to the induction of interferon-β

(2008) Jonathan C Kagan et al.   NATURE IMMUNOLOGY