Inflammatory stimuli induce inhibitory S-nitrosylation of the deacetylase SIRT1 to increase acetylation and activation of p53 and p65

Inducible nitric oxide synthase (iNOS) in muscle wasting syndrome, sarcopenia, and cachexia

(2016) Derek T. Hall et al.   Aging-US

Plasma Lipopolysaccharide Is Closely Associated With Glycemic Control and Abdominal Obesity: Evidence from bariatric surgery

(2013) M. Troseid et al.   DIABETES CARE

The loss of Sirt1 in mouse pancreatic beta cells impairs insulin secretion by disrupting glucose sensing

(2013) L. Luu et al.   DIABETOLOGIA

SIRT1 Protein, by Blocking the Activities of Transcription Factors FoxO1 and FoxO3, Inhibits Muscle Atrophy and Promotes Muscle Growth

(2013) Donghoon Lee et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Stabilising cysteinyl thiol oxidation and nitrosation for proteomic analysis

(2013) Shibani Ratnayake et al.   Journal of Proteomics

S-Nitrosylation of parkin as a novel regulator of p53-mediated neuronal cell death in sporadic Parkinson’s disease

(2013) Carmen R Sunico et al.   Molecular Neurodegeneration

Aberrant Protein S-Nitrosylation in Neurodegenerative Diseases

(2013) Tomohiro Nakamura et al.   NEURON

Investigations into Potential Extrasynaptic Communication between the Dopaminergic and Nitrergic Systems

(2012) M. Mitkovski et al.   Frontiers in Physiology

Sir2 deletion prevents lifespan extension in 32 long-lived mutants

(2011) Joe R. Delaney et al.   AGING CELL

Cell Death, Damage-Associated Molecular Patterns, and Sterile Inflammation in Cardiovascular Disease

(2011) Yue Zheng et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Hepatic overexpression of SIRT1 in mice attenuates endoplasmic reticulum stress and insulin resistance in the liver

(2011) Yu Li et al.   FASEB JOURNAL

Liver-specific Inducible Nitric-oxide Synthase Expression Is Sufficient to Cause Hepatic Insulin Resistance and Mild Hyperglycemia in Mice

(2011) Shohei Shinozaki et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Hepatic Sirt1 deficiency in mice impairs mTorc2/Akt signaling and results in hyperglycemia, oxidative damage, and insulin resistance

(2011) Rui-Hong Wang et al.   JOURNAL OF CLINICAL INVESTIGATION

Increased Intestinal Permeability Correlates with Sigmoid Mucosa alpha-Synuclein Staining and Endotoxin Exposure Markers in Early Parkinson's Disease

(2011) Christopher B. Forsyth et al.   PLoS One

Nitric Oxide Signaling and Nitrosative Stress in Neurons: Role for S-Nitrosylation

(2010) Neelam Shahani et al.   ANTIOXIDANTS & REDOX SIGNALING

Gene disruption of caspase-3 prevents MPTP-induced Parkinson’s disease in mice

(2010) Marina Yamada et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

RETRACTED: SIRT1 Suppresses β-Amyloid Production by Activating the α-Secretase Gene ADAM10

(2010) Gizem Donmez et al.   CELL

Low Doses of Lipopolysaccharide and Minimally Oxidized Low-Density Lipoprotein Cooperatively Activate Macrophages via Nuclear Factor κB and Activator Protein-1

(2010) Philipp Wiesner et al.   CIRCULATION RESEARCH

S -Nitrosylation in Cardiovascular Signaling

(2010) Brian Lima et al.   CIRCULATION RESEARCH

p53 and NF-κB: different strategies for responding to stress lead to a functional antagonism

(2010) Prashanth Ak et al.   FASEB JOURNAL

Toll-like receptor 4 mediates lipopolysaccharide-induced muscle catabolism via coordinate activation of ubiquitin-proteasome and autophagy-lysosome pathways

(2010) Alexander Doyle et al.   FASEB JOURNAL

GAPDH mediates nitrosylation of nuclear proteins

(2010) Michael D. Kornberg et al.   NATURE CELL BIOLOGY

Hsp27 inhibits IKKβ-induced NF-κB activity and skeletal muscle atrophy

(2009) Stephen L. Dodd et al.   FASEB JOURNAL

Hindlimb Ischemia/Reperfusion-Induced Remote Injury to the Small Intestine: Role of Inducible Nitric-Oxide Synthase-Derived Nitric Oxide

(2009) K. Katada et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Transcriptional repression of p53 by parkin and impairment by mutations associated with autosomal recessive juvenile Parkinson's disease

(2009) Cristine Alves da Costa et al.   NATURE CELL BIOLOGY

Determination of the class and isoform selectivity of small-molecule histone deacetylase inhibitors

(2008) Nagma Khan et al.   BIOCHEMICAL JOURNAL

SirT1 Gain of Function Increases Energy Efficiency and Prevents Diabetes in Mice

(2008) Alexander S. Banks et al.   Cell Metabolism