Inflammatory Cytokines at the Summits of Pathological Signal Cascades in Brain Diseases

Regional Neural Activation Defines a Gateway for Autoreactive T Cells to Cross the Blood-Brain Barrier

(2012) Yasunobu Arima et al.   CELL

The discovery of natalizumab, a potent therapeutic for multiple sclerosis

(2012) Lawrence Steinman   JOURNAL OF CELL BIOLOGY

Lessons learned at the intersection of immunology and neuroscience

(2012) Lawrence Steinman   JOURNAL OF CLINICAL INVESTIGATION

Immune response during interferon beta-1b treatment in patients with multiple sclerosis who experienced relapses and those who were relapse-free in the START study

(2012) Suhayl Dhib-Jalbut et al.   JOURNAL OF NEUROIMMUNOLOGY

Serum levels of IL-17A in patients with relapsing–remitting multiple sclerosis treated with interferon-β

(2012) Rodica Bălaşa et al.   Multiple Sclerosis Journal

Protective effect of an elastase inhibitor in a neuromyelitis optica-like disease driven by a peptide of myelin oligodendroglial glycoprotein

(2012) Katja Herges et al.   Multiple Sclerosis Journal

TNF receptor 1 genetic risk mirrors outcome of anti-TNF therapy in multiple sclerosis

(2012) Adam P. Gregory et al.   NATURE

Optimization of current and future therapy for autoimmune diseases

(2012) Lawrence Steinman et al.   NATURE MEDICINE

Treating inflammation by blocking interleukin-1 in a broad spectrum of diseases

(2012) Charles A. Dinarello et al.   NATURE REVIEWS DRUG DISCOVERY

The vagus nerve and the inflammatory reflex—linking immunity and metabolism

(2012) Valentin A. Pavlov et al.   Nature Reviews Endocrinology

Serum IL-17F does not predict poor response to IM IFN -1a in relapsing-remitting MS

(2012) S. E. Bushnell et al.   NEUROLOGY

Interferon-  Therapy Against EAE Is Effective Only When Development of the Disease Depends on the NLRP3 Inflammasome

(2012) M. Inoue et al.   Science Signaling

Excessive Biologic Response to IFNβ Is Associated with Poor Treatment Response in Patients with Multiple Sclerosis

(2011) Richard A. Rudick et al.   PLoS One

Interferon-β exacerbates Th17-mediated inflammatory disease

(2011) Robert C. Axtell et al.   TRENDS IN IMMUNOLOGY

T helper type 1 and 17 cells determine efficacy of interferon-β in multiple sclerosis and experimental encephalomyelitis

(2010) Robert C Axtell et al.   NATURE MEDICINE

Interleukin 6 in autoimmune and inflammatory diseases: a personal memoir

(2010) Toshio HIRANO   PROCEEDINGS OF THE JAPAN ACADEMY SERIES B-PHYSICAL AND BIOLOGICAL SCIENCES

Innate and Adaptive Autoimmunity Directed to the Central Nervous System

(2009) Roopa Bhat et al.   NEURON

Good response to IL‐1β blockade by anakinra in a 23‐year‐old CINCA/NOMID patient without mutations in theCIAS1gene. Cytokine profiles and functional studies

(2008) C. M. Hedrich et al.   SCANDINAVIAN JOURNAL OF RHEUMATOLOGY