Direct Binding Between Orai1 and AC8 Mediates Dynamic Interplay Between Ca2+ and cAMP Signaling

Cooperativeness of Orai Cytosolic Domains Tunes Subtype-specific Gating

(2011) Irene Frischauf et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

SOCIC: The store-operated calcium influx complex

(2010) Luis Vaca   CELL CALCIUM

AKAP79/150 Interacts with AC8 and Regulates Ca2+-dependent cAMP Synthesis in Pancreatic and Neuronal Systems

(2010) Debbie Willoughby et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A single lysine in the N-terminal region of store-operated channels is critical for STIM1-mediated gating

(2010) Annette Lis et al.   JOURNAL OF GENERAL PHYSIOLOGY

CRAC channelopathies

(2010) Stefan Feske   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

The CRAC Channel Activator STIM1 Binds and Inhibits L-Type Voltage-Gated Calcium Channels

(2010) C. Y. Park et al.   SCIENCE

The Calcium Store Sensor, STIM1, Reciprocally Controls Orai and CaV1.2 Channels

(2010) Y. Wang et al.   SCIENCE

A minimal regulatory domain in the C terminus of STIM1 binds to and activates ORAI1 CRAC channels

(2009) Takumi Kawasaki et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

STIM1 Clusters and Activates CRAC Channels via Direct Binding of a Cytosolic Domain to Orai1

(2009) Chan Young Park et al.   CELL

ORAI1 and STIM1 deficiency in human and mice: roles of store-operated Ca2+entry in the immune system and beyond

(2009) Stefan Feske   IMMUNOLOGICAL REVIEWS

Separate Elements within a Single IQ-like Motif in Adenylyl Cyclase Type 8 Impart Ca2+/Calmodulin Binding and Autoinhibition

(2009) David A. MacDougall et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Cytosolic Homomerization and a Modulatory Domain within STIM1 C Terminus Determine Coupling to ORAI1 Channels

(2009) Martin Muik et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Glycogen Synthase Kinase 3β Interaction Protein Functions as an A-kinase Anchoring Protein

(2009) Christian Hundsrucker et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Distinct pools of cAMP centre on different isoforms of adenylyl cyclase in pituitary-derived GH3B6 cells

(2009) S. Wachten et al.   JOURNAL OF CELL SCIENCE

Direct demonstration of discrete Ca2+ microdomains associated with different isoforms of adenylyl cyclase

(2009) D. Willoughby et al.   JOURNAL OF CELL SCIENCE

Capacitative Ca2+ Entry via Orai1 and Stromal Interacting Molecule 1 (STIM1) Regulates Adenylyl Cyclase Type 8

(2009) A. C. L. Martin et al.   MOLECULAR PHARMACOLOGY

Store-operated cyclic AMP signalling mediated by STIM1

(2009) Konstantinos Lefkimmiatis et al.   NATURE CELL BIOLOGY

STIM1 converts TRPC1 from a receptor-operated to a store-operated channel: Moving TRPC1 in and out of lipid rafts

(2008) Sampieri Alicia et al.   CELL CALCIUM

Distinct Mechanisms of Regulation by Ca2+/Calmodulin of Type 1 and 8 Adenylyl Cyclases Support Their Different Physiological Roles

(2008) Nanako Masada et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The CRAC channel consists of a tetramer formed by Stim-induced dimerization of Orai dimers

(2008) Aubin Penna et al.   NATURE

Functional stoichiometry of the unitary calcium-release-activated calcium channel

(2008) W. Ji et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Regulation of the cellular localization and function of human transient receptor potential channel 1 by other members of the TRPC family

(2007) Salgado Alfonso et al.   CELL CALCIUM

Orai1 subunit stoichiometry of the mammalian CRAC channel pore

(2007) Olivier Mignen et al.   JOURNAL OF PHYSIOLOGY-LONDON