Pharmacologically blocking p53-dependent apoptosis protects intestinal stem cells and mice from radiation
出版年份 2015 全文链接
标题
Pharmacologically blocking p53-dependent apoptosis protects intestinal stem cells and mice from radiation
作者
关键词
-
出版物
Scientific Reports
Volume 5, Issue 1, Pages -
出版商
Springer Nature
发表日期
2015-04-10
DOI
10.1038/srep08566
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Ionizing irradiation induces acute haematopoietic syndrome and gastrointestinal syndrome independently in mice
- (2014) Brian J. Leibowitz et al. Nature Communications
- Lgr5+ Stem Cells Are Indispensable for Radiation-Induced Intestinal Regeneration
- (2013) Ciara Metcalfe et al. Cell Stem Cell
- Intestinal label-retaining cells are secretory precursors expressing Lgr5
- (2013) Simon J. A. Buczacki et al. NATURE
- Induction of intestinal stem cells by R-spondin 1 and Slit2 augments chemoradioprotection
- (2013) Wei-Jie Zhou et al. NATURE
- ADAR1 is essential for intestinal homeostasis and stem cell maintenance
- (2013) W Qiu et al. Cell Death & Disease
- A nomenclature for intestinal in vitro cultures
- (2012) Matthias Stelzner et al. AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY
- Wnt/β-Catenin Signaling and Disease
- (2012) Hans Clevers et al. CELL
- Identifying the Stem Cell of the Intestinal Crypt: Strategies and Pitfalls
- (2012) Nick Barker et al. Cell Stem Cell
- Therapeutic resistance resulting from mutations in Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR signaling pathways
- (2011) James A. McCubrey et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Uncoupling p53 Functions in Radiation-Induced Intestinal Damage via PUMA and p21
- (2011) B. J. Leibowitz et al. MOLECULAR CANCER RESEARCH
- Phosphorylation of Tip60 by GSK-3 Determines the Induction of PUMA and Apoptosis by p53
- (2011) Céline Charvet et al. MOLECULAR CELL
- Deletion of Puma protects hematopoietic stem cells and confers long-term survival in response to high-dose -irradiation
- (2010) H. Yu et al. BLOOD
- Deletion of proapoptotic Puma selectively protects hematopoietic stem and progenitor cells against high-dose radiation
- (2010) L. Shao et al. BLOOD
- A New Class of Molecular Targeted Radioprotectors: GSK-3β Inhibitors
- (2010) Dinesh K. Thotala et al. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS
- Radioprotectors and Mitigators of Radiation-Induced Normal Tissue Injury
- (2010) D. Citrin et al. ONCOLOGIST
- p53 post-translational modification: deregulated in tumorigenesis
- (2010) Chao Dai et al. TRENDS IN MOLECULAR MEDICINE
- Glycogen synthase kinase 3: more than a namesake
- (2009) Geetha Vani Rayasam et al. BRITISH JOURNAL OF PHARMACOLOGY
- Blinded by the Light: The Growing Complexity of p53
- (2009) Karen H. Vousden et al. CELL
- Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche
- (2009) Toshiro Sato et al. NATURE
- Growth factors protect intestinal stem cells from radiation-induced apoptosis by suppressing PUMA through the PI3K/AKT/p53 axis
- (2009) W Qiu et al. ONCOGENE
- R-Spondin1 protects mice from chemotherapy or radiation-induced oral mucositis through the canonical Wnt/ -catenin pathway
- (2009) J. Zhao et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Inhibition of Glycogen Synthase Kinase 3 Attenuates Neurocognitive Dysfunction Resulting from Cranial Irradiation
- (2008) D. K. Thotala et al. CANCER RESEARCH
- PUMA Regulates Intestinal Progenitor Cell Radiosensitivity and Gastrointestinal Syndrome
- (2008) Wei Qiu et al. Cell Stem Cell
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started