Article
Biochemistry & Molecular Biology
Kanae Suzuki, Misato Iwatsu, Takayuki Mokudai, Maiko Furuya, Kotone Yokota, Hiroyasu Kanetaka, Masaya Shimabukuro, Taishi Yokoi, Masakazu Kawashita
Summary: In this study, titania (TiO2) co-doped with silver (Ag) at 2.5 at.% and copper (Cu) at 4.9 at.% was formed on Ti substrates. The co-doped TiO2 showed osteoconductivity by forming apatite in a simulated body fluid. It also exhibited antibacterial activity against Escherichia coli, which was enhanced by visible-light irradiation. Dental implants with this co-doped TiO2 on their surface may reduce the risk of peri-implantitis.
Article
Nanoscience & Nanotechnology
Yu Zhao, Ran Lu, Xin Wang, Xiaochen Huai, Caiyun Wang, Yuji Wang, Su Chen
Summary: The study successfully fabricated the H-TNTs/f-Ti composite with enhanced visible light-induced photoelectric response and more hydroxyl functional groups, which can improve the biocompatibility of dental implants and inhibit bacterial growth effectively.
Article
Biochemistry & Molecular Biology
Ashkan Bahadoran, Nooshin Bahadoran Baghbadorani, Jeffrey Roshan De Lile, Saeid Masudy-Panah, Behzad Sadeghi, Jinghan Li, Seeram Ramakrishna, Qinglei Liu, Baadal Jushi Janani, Ali Fakhri
Summary: This project investigates Ag doped Sn3O4 nanostructure immobilized on hyperbranched polypyrrole. The product is synthesized by hydrothermal synthesis method. The surface and structural characteristics are studied through instrumental analysis. The nanocomposite exhibits excellent photocatalytic activity under visible light.
JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY
(2022)
Article
Materials Science, Multidisciplinary
Zahra Sadat Hosseini, Farzane Haghparast, Amir Ali Masoudi, Abdollah Mortezaali
Summary: This study successfully enhanced the photocatalytic activity of TiO2 nanoparticles by adjusting the substrate surface roughness and thermal treatment. The sample prepared on the roughest substrate showed the smallest nanoparticle size, the highest surface roughness, and hydrophilicity, as well as strong optical absorption. Under visible light illumination, this sample achieved efficient degradation of pollutants.
MATERIALS CHEMISTRY AND PHYSICS
(2022)
Article
Environmental Sciences
V Beena, S. Ajitha, S. L. Rayar, A. Ahmad, M. Khan, K. M. Abualnaja, N. AlMasoud, M. Ouladsmne
Summary: Environmental pollution is a major concern in today's world. This study focuses on the synthesis of Ag-doped ZnSe nanoparticles and investigates their photocatalytic dye degradation and antibacterial activity. The results show that Ag-doped ZnSe nanoparticles have high efficiency in degrading methyl orange under visible light irradiation and exhibit antibacterial activity against S. aureus and E. coli bacteria.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL SCIENCE AND TECHNOLOGY
(2022)
Article
Materials Science, Multidisciplinary
Mai Mersal, Gehad G. Mohamed, Abdallah F. Zedan
Summary: Alcohol oxidation is an important chemical reaction of interest in energy and industrial sectors. In this study, n-TiO2@WO3 heterojunction photocatalysts were prepared and their catalytic activity towards methanol oxidation under visible-light was investigated. The hybrid photocatalyst showed enhanced activity compared to pure counterparts.
Article
Green & Sustainable Science & Technology
Moslem Abdollahi, Afsanehsadat Larimi, Zhi Jiang, Farhad Khorasheh, Cyrus Ghotbi
Summary: The purpose of this study was to modify the properties of TiO2 by adding carbon and copper, in order to create an active nanostructure for photocatalytic oxidative desulfurization under visible light. By investigating different parameters, the researchers identified the catalyst with the best performance and explained its advantages.
JOURNAL OF CLEANER PRODUCTION
(2022)
Article
Chemistry, Applied
Shubin Yang, Bunsho Ohtani
Summary: In this study, a Rh-TiO2 composite material was prepared by oxidizing Rh(III) species to Rh(IV) in an aqueous solution, which showed enhanced photocatalytic activity. XPS analysis confirmed the presence of Rh(IV) species in the composite, and the effect of Rh/Ti molar ratio on the photocatalytic activity was studied, demonstrating that Rh doping improved the visible-light absorption and overall performance of the composite.
Article
Materials Science, Multidisciplinary
Ryusuke Koizumi, Kyosuke Ueda, Koyu Ito, Kouetsu Ogasawara, Hiroyasu Kanetaka, Takayuki Mokudai, Takayuki Narushima
Summary: In this study, carbon and nitrogen co-doped single-phase rutile TiO2 films were fabricated on Ti substrates, exhibiting antibacterial activity against Escherichia coli under visible-light irradiation. The films had a double-layered structure with an inner layer containing carbon and nitrogen and an outer layer without carbon or nitrogen. The excitation of electrons and holes in the inner layer contributed to the visible-light responsiveness, and the bonding strength between the film and Ti substrate exceeded 60 MPa.
Article
Green & Sustainable Science & Technology
Sangmo Kang, Jungho Hwang
Summary: This study presents a strategy for fabricating reduced graphene oxide-wrapped Ag/TiO2 nanofibers and demonstrates their efficient CO2 photoreduction performance under visible light.
JOURNAL OF CLEANER PRODUCTION
(2022)
Article
Engineering, Chemical
Shuang Wang, Le She, Qiao Zheng, Yi Yang, Yingying Song, Limiao Chen
Summary: Photocatalytic CO2 reduction into chemical fuels is a promising strategy for CO2 conversion and solar energy utilization, but conversion efficiency remains a challenge. In this study, Ag-ion-doped CuV2O6 nanowires with abundant oxygen vacancies were prepared and used as catalysts for CO2 photoreduction. The Ag-doped CuV2O6 nanowires exhibited enhanced visible-light absorption ability, abundant oxygen vacancies, and high separation/transfer efficiency of electron-hole pairs, resulting in excellent photocatalytic performance for CO2 reduction. The optimized Ag-doped CuV2O6 nanowires showed a significantly enhanced CO evolution rate under visible-light irradiation compared to pure CuV2O6 nanowires. This work provides a valid strategy for improving visible-light photocatalytic CO2 reduction using CuV2O6 nanowires.
INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH
(2023)
Article
Biotechnology & Applied Microbiology
Quanming Zhao, Jieshi Wu, Yankun Li, Ruisheng Xu, Xingyuan Zhu, Yang Jiao, Rui Luo, Xiaohui Ni
Summary: This study introduced bioactive Si and Ag onto a Ti surface through plasma oxidation, forming a porous coating. The physical and chemical properties of the coating were characterized, and the osteogenic and antibacterial properties were evaluated. The results showed that Si/Ag-coated Ti implants promoted cell proliferation and mineralization, and had certain antibacterial properties.
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
(2022)
Article
Engineering, Environmental
Rudzani Ratshiedana, Olayemi Jola Fakayode, Ajay Kumar Mishra, Alex Tawanda Kuvarega
Summary: The study focuses on the impact of silver ion doping on the photocatalytic activity of titanium dioxide for the degradation of tartrazine. Results show that optimal degradation of tartrazine can be achieved with a certain amount of doping, suggesting potential applications for removing similar organic pollutants from water.
JOURNAL OF WATER PROCESS ENGINEERING
(2021)
Article
Materials Science, Multidisciplinary
Qing Lin, Shuyi Xia, Shuiping Li, Hailuo Fu, Dong Liang, Zhao Wang, Xiaojuan Zhang
Summary: Au@α-Fe2O3 nanoparticles with a well-defined structure were synthesized using hydrothermal and magnetron sputtering methods. After depositing 4.6% Au, the Au@α-Fe2O3 showed a new absorption peak at 550 nm in the UV-Vis spectrum, and its bandgap decreased from 2.20 to 1.93 eV. The fluorescence intensity and electrochemical impedance of 4.6% Au@α-Fe2O3 decreased significantly, while the photocurrent increased from 0.20 to 0.56 μA cm-2. The Au nanoparticles enhanced visible-light absorption and hindered electron-hole pair recombination in Au@α-Fe2O3 particles. The photocatalytic efficiency of Au@α-Fe2O3 particles was approximately 1 times higher than that of α-Fe2O3 particles.
MATERIALS CHEMISTRY AND PHYSICS
(2023)
Article
Engineering, Environmental
Eleni Bletsa, Padryk Merkl, Thomas Thersleff, Staffan Normark, Birgitta Henriques-Normark, Georgios A. Sotiriou
Summary: Researchers have developed a durable antibacterial coating material that is active under visible light. It can be used on medical devices such as catheters, ventilators, and wound meshes to eradicate biofilms multiple times in a short period, without significant cytotoxicity to mammalian cells.
CHEMICAL ENGINEERING JOURNAL
(2023)
Article
Biochemistry & Molecular Biology
Jaya Prakash Mandal, Chiou-Nan Shiue, Yen-Cheng Chen, Ming-Che Lee, Hsueh-Hui Yang, Hsin-Hou Chang, Chi-Tan Hu, Pei-Chen Liao, Lin-Ching Hui, Ren-In You, Wen-Sheng Wu
Summary: This study revealed that PKC delta interacts with mtROS to trigger HSP60 oxidation for the release of RKIP, activating MAPK and regulating cell migration and G1 cell cycle arrest in HCC. Targeted therapy against key players like PKC delta, RKIP, and HSP60 shows promise in preventing HCC progression.
FREE RADICAL BIOLOGY AND MEDICINE
(2021)
Article
Immunology
Te-Sheng Lien, Der-Shan Sun, Cheng-Yeu Wu, Hsin-Hou Chang
Summary: The study found that endothelial cell death plays an important role in dengue hemorrhagic fever, and this death can be attenuated by inhibiting the Nlrp3 inflammasome. The results suggest that the Nlrp3 inflammasome may be a potential therapeutic target for treating DHF.
FRONTIERS IN IMMUNOLOGY
(2021)
Article
Cell & Tissue Engineering
Tso-Fu Wang, Guan-Ling Lin, Sung-Chao Chu, Chang-Chin Chen, Yu-Shan Liou, Hsin-Hou Chang, Der-Shan Sun
Summary: AQP0 has been identified as a surface protein in early- and late-stage erythropoiesis precursors, providing a marker for distinguishing normal and dysregulated erythropoiesis. Downregulation of AQP0 in patients with dyserythropoiesis suggests its critical role in erythropoiesis, making AQP0(high) levels in early erythroid precursor cells a potential biomarker for related diseases.
STEM CELL RESEARCH & THERAPY
(2021)
Article
Immunology
Te-Sheng Lien, Der-Shan Sun, Shih-Che Hung, Wen-Sheng Wu, Hsin-Hou Chang
Summary: The study shows that the dengue virus envelope protein domain III can induce neutrophil NETosis processes, and inhibition of Nlrp3 inflammasome can suppress this process, providing a new molecular target for treating dengue-induced inflammatory pathogenesis.
FRONTIERS IN IMMUNOLOGY
(2021)
Article
Immunology
Te-Sheng Lien, Hao Chan, Der-Shan Sun, Jhen-Cheng Wu, You-Yen Lin, Guan-Ling Lin, Hsin-Hou Chang
Summary: The study suggests that EIII could be considered as a virulence factor of DENV, and that Nlrp3 inflammasome is a feasible target for developing therapeutic approaches against dengue-induced platelet defects. Blockages of EIII-induced platelet signaling using inhibitors markedly ameliorated DENV- and EIII-induced thrombocytopenia, platelet activation, and cell death.
FRONTIERS IN IMMUNOLOGY
(2021)
Article
Multidisciplinary Sciences
Chiao-Yi Huang, Wei-Sheng Yu, Geng-Chia Liu, Shih-Che Hung, Jen-Hsiang Chang, Jen-Che Chang, Chia-Liang Cheng, Der-Shan Sun, Ming-Der Lin, Wen-Ying Lin, Yin-Jeh Tzeng, Hsin-Hou Chang
Summary: The study found that TiO2NP-induced injury and mortality in zebrafish are positively associated with treatment dosages, increased motility, and increased bacterial load in the gills. Metagenomic analysis revealed that opportunistic bacterial infections secondary to TiO2NP-induced injury may contribute to mortality in zebrafish.
Article
Cell Biology
Tam Minh Ly, Yen-Cheng Chen, Ming-Che Lee, Chi-Tan Hu, Chuan-Chu Cheng, Hsin-Hou Chang, Ren-In You, Wen-Sheng Wu
Summary: This study demonstrates that SNA collaborates with EGR1 and SP1 to upregulate mesenchymal markers, including MMP9 and ZEB1. Analyses reveal that the SNA-binding motif and EGR1/SP1 overlapping region are crucial for the transcriptional activation of these mesenchymal genes. Additionally, a common sequence architecture is found in the promoter regions of other SNA-upregulated mesenchymal markers, suggesting a general model for SNA-upregulated mesenchymal genes.
Article
Immunology
Shih-Che Hung, Lu-Chu Ke, Te-Sheng Lien, Hsuan-Shun Huang, Der-Shan Sun, Chia-Liang Cheng, Hsin-Hou Chang
Summary: Nanodiamonds have been developed as carriers for in vivo diagnostic and therapeutic uses, but their hemocompatibility has not been well studied. This study found that 50 nm nanodiamonds induce platelet activation and pyroptosis, leading to thrombocytopenia in mice. However, blocking P-selectin, reactive oxygen species (ROS), and Nlrp3 inflammasome pathways can significantly reduce these adverse effects.
FRONTIERS IN IMMUNOLOGY
(2022)
Article
Medicine, General & Internal
Tso-Fu Wang, Yu-Shan Liou, Hsin-Hou Chang, Shang-Hsien Yang, Chi-Cheng Li, Jen-Hung Wang, Der-Shan Sun
Summary: This study investigated the correlation between body mass index (BMI), proinflammatory cytokine levels, and hematopoietic stem cell (HSC) mobilization triggered by granulocyte colony-stimulating factor (G-CSF). The results showed that BMI was positively correlated with G-CSF-induced HSC mobilization, and good mobilizers had higher BMI and proinflammatory cytokine levels compared to poor mobilizers.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Biochemistry & Molecular Biology
Subhashree Pethaperumal, Shih-Che Hung, Te-Sheng Lien, Der-Shan Sun, Hsin-Hou Chang
Summary: This study found that platelets play a protective role in stress-induced GI injury, and that P-selectin is a molecular target for managing stress-induced GI tract injury.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Multidisciplinary Sciences
Chi-Cheng Li, Sian-Ming Jhou, Yi-Chen Li, Jhih-Wei Ciou, You-Yen Lin, Shih-Che Hung, Jen-Hsiang Chang, Jen-Che Chang, Der-Shan Sun, Ming-Lun Chou, Hsin-Hou Chang
Summary: There is a controversial debate on the effect of titanium dioxide nanoparticles (TiO2 NPs) on plants. This study reveals that the controversy is due to the dosage effect, as appropriate dosages of TiO2 NPs positively affect seed germination and growth, while overdosing leads to tissue damage. These findings have significant implications for agricultural applications, sustainable development, and environmental preservation.
SCIENTIFIC REPORTS
(2022)
Article
Biochemistry & Molecular Biology
Te-Sheng Lien, Der-Shan Sun, Wen-Sheng Wu, Hsin-Hou Chang
Summary: This study aimed to investigate the cytotoxicity of EIII-coated silica nanoparticles (EIII-SNPs) on endothelial cells and their potential role in hemorrhage pathogenesis. The results showed that EIII-SNPs induced greater endothelial cytotoxicity in vitro than EIII or silica nanoparticles alone. Moreover, the combination of EIII-SNPs and antiplatelet antibodies resulted in more severe hemorrhage pathogenesis in mice compared to single treatments. These findings suggest that EIII-coated nanoparticles could be used to develop a dengue hemorrhage pathogenesis model and highlight the potential role of EIII in DHF pathogenesis.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Biochemistry & Molecular Biology
Bijaya Siwakoti, Te-Sheng Lien, You-Yen Lin, Subhashree Pethaperumal, Shih-Che Hung, Der-Shan Sun, Ching-Feng Cheng, Hsin-Hou Chang
Summary: Metformin, a commonly used drug for type 2 diabetes, has been found to have potential applications in anti-aging, cellular protection, and anti-inflammation. Research shows that metformin can protect the gastrointestinal tract from injury caused by psychological stress. This protection is regulated by the ATF3 gene.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Biochemistry & Molecular Biology
Chi-Cheng Li, Rina Munalisa, Hsuan-Yun Lee, Te-Sheng Lien, Hao Chan, Shih-Che Hung, Der-Shan Sun, Ching-Feng Cheng, Hsin-Hou Chang
Summary: Psychological stress is widely acknowledged as a major contributor to immunosuppression, rendering individuals more susceptible to various diseases. The complex interplay between the nervous, endocrine, and immune systems underlies stress-induced immunosuppression.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Review
Medicine, General & Internal
Der-Shan Sun, Hsin-Hou Chang
Summary: Metabolic regulations are important for maintaining body homeostasis. ATF3 and NRF2 play critical roles in cell function, metabolism, and inflammation/anti-inflammation regulations. Recent findings have revealed the involvement of metabolites like itaconate and succinate in metabolism and immune modulation. Itaconate exerts anti-inflammatory effects by regulating ATF3 and NRF2 pathways and inhibiting succinate-mediated inflammatory processes.
TZU CHI MEDICAL JOURNAL
(2022)
