4.7 Article

PCBs and OH-PCBs in polar bear mother-cub pairs: A comparative plasma levels in 1998 and 2008

期刊

SCIENCE OF THE TOTAL ENVIRONMENT
卷 417, 期 -, 页码 117-128

出版社

ELSEVIER
DOI: 10.1016/j.scitotenv.2011.12.033

关键词

Svalbard; Polychlorinated biphenyls; Hydroxylated PCB metabolites; Climate change; Maternal transfer; Risk assessment

资金

  1. Research Council of Norway

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The aim of this study was to examine the plasma concentrations and prevalence of polychlorinated biphenyls (PCBs) and hydroxylated PCB-metabolites (OH-PCBs) in polar bear (Ursus maritimus) mothers (n = 26) and their 4 months old cubs-of-the-year (n = 38) from Svalbard to gain insight into the mother-cub transfer, biotransformation and to evaluate the health risk associated with the exposure to these contaminants. As samplings were performed in 1997/1998 and 2008, we further investigated the differences in levels and pattern of PCBs between the two sampling years. The plasma concentrations of Sigma(21)PCBs (1997/1998: 5710 +/- 3090 ng/g lipid weight [lw], 2008: 2560 +/- 1500 ng/g lw) and Sigma 6OH-PCBs (1997/1998: 228 +/- 60 ng/g wet weight [ww], 2008: 80 +/- 38 ng/g ww) in mothers were significantly lower in 2008 compared to in 1997/1998. In cubs, the plasma concentrations of Sigma(21)PCBs (1997/1998: 14680 +/- 5350 ng/g lw, 2008: 6070 +/- 2590 ng/g lw) and Sigma 6OH-PCBs (1997/1998: 98 +/- 23 ng/g ww, 2008: 49 +/- 21 ng/g ww) were also significantly lower in 2008 than in 1997/1998. Sigma(12)PCBs in cubs was 2.7 +/- 0.7 times higher than in their mothers. This is due to a significant maternal transfer of these contaminants. In contrast, 1,Sigma 6OH-PCBs in cubs were approximately 0.53 +/- 0.16 times the concentration in their mothers. This indicates a lower maternal transfer of OH-PCBs compared to PCBs. The majority of the metabolite/precursor-ratios were lower in cubs compared to mothers. This may indicate that cubs have a lower endogenous capacity to biotransform PCBs to OH-PCBs than polar bear mothers. Exposure to PCBs and OH-PCBs is a potential health risk for polar bears, and the levels of PCBs and OH-PCBs in cubs from 2008 were still above levels associated with health effects in humans and wildlife. (C) 2012 Elsevier B.V. All rights reserved.

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