Spectrin: Structure, function and disease

Release of an ∼55kDa fragment containing the actin-binding domain of β-spectrin by caspase-8 during FND-induced apoptosis depends on the presence of protein 4.1

(2013) Monika Toporkiewicz et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

The common hereditary elliptocytosis-associated  -spectrin L260P mutation perturbs erythrocyte membranes by stabilizing spectrin in the closed dimer conformation

(2013) S. L. Harper et al.   BLOOD

Mena/VASP and αII-Spectrin complexes regulate cytoplasmic actin networks in cardiomyocytes and protect from conduction abnormalities and dilated cardiomyopathy

(2013) Peter M Benz et al.   Cell Communication and Signaling

The giant spectrin βV couples the molecular motors to phototransduction and Usher syndrome type I proteins along their trafficking route

(2013) Samantha Papal et al.   HUMAN MOLECULAR GENETICS

Non-erythroid alpha spectrin prevents telomere dysfunction after DNA interstrand cross-link damage

(2013) Pan Zhang et al.   NUCLEIC ACIDS RESEARCH

βIII Spectrin Regulates the Structural Integrity and the Secretory Protein Transport of the Golgi Complex

(2012) Laia Salcedo-Sicilia et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Identification of a Novel Role for Dematin in Regulating Red Cell Membrane Function by Modulating Spectrin-Actin Interaction

(2012) Ichiro Koshino et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Thermal stability of chicken brain α-spectrin repeat 17: a spectroscopic study

(2012) Annette K. Brenner et al.   JOURNAL OF BIOMOLECULAR NMR

High-Resolution Crystal Structure of Spectrin SH3 Domain Fused with a Proline-Rich Peptide

(2012) Liubov V. Gushchina et al.   JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS

Sialoglycosylation of RBC in Visceral Leishmaniasis Leads to Enhanced Oxidative Stress, Calpain-Induced Fragmentation of Spectrin and Hemolysis

(2012) Sajal Samanta et al.   PLoS One

Drosophilasosiefunctions with βH-Spectrin and actin organizers in cell migration, epithelial morphogenesis and cortical stability

(2012) Olivier Urwyler et al.   Biology Open

Novel role for the Lu/BCAM–spectrin interaction in actin cytoskeleton reorganization

(2011) Emmanuel Collec et al.   BIOCHEMICAL JOURNAL

Spectrin-based skeleton as an actor in cell signaling

(2011) B. Machnicka et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Cell organization, growth, and neural and cardiac development require  II-spectrin

(2011) M. C. Stankewich et al.   JOURNAL OF CELL SCIENCE

Enterohaemorrhagic Escherichia coli requires the spectrin cytoskeleton for efficient attachment and pedestal formation on host cells

(2011) Tyson Joel Ruetz et al.   MICROBIAL PATHOGENESIS

Key Amino Acid Residues of Ankyrin-Sensitive Phosphatidylethanolamine/Phosphatidylcholine-Lipid Binding Site of βI-Spectrin

(2011) Marcin Wolny et al.   PLoS One

Glycosylation of Erythrocyte Spectrin and Its Modification in Visceral Leishmaniasis

(2011) Sajal Samanta et al.   PLoS One

Crystal structure and functional interpretation of the erythrocyte spectrin tetramerization domain complex

(2010) J. J. Ipsaro et al.   BLOOD

Dynamic Regulation of CD45 Lateral Mobility by the Spectrin-Ankyrin Cytoskeleton of T Cells

(2010) Christopher W. Cairo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Fused α-β “Mini-spectrin” Mimics the Intact Erythrocyte Spectrin Head-to-head Tetramer

(2010) Sandra L. Harper et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Comprehensive Model of the Spectrin Divalent Tetramer Binding Region Deduced Using Homology Modeling and Chemical Cross-linking of a Mini-spectrin

(2010) Donghai Li et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Knockdown of αII spectrin in normal human cells by siRNA leads to chromosomal instability and decreased DNA interstrand cross-link repair

(2009) Laura W. McMahon et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Phospholipid-induced structural changes to an erythroid β spectrin ankyrin-dependent lipid-binding site

(2008) Aleksander Czogalla et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Cytoskeleton assembly at endothelial cell–cell contacts is regulated by αII-spectrin–VASP complexes

(2008) Peter M. Benz et al.   JOURNAL OF CELL BIOLOGY

Organizing the fluid membrane bilayer: diseases linked to spectrin and ankyrin

(2007) Vann Bennett et al.   TRENDS IN MOLECULAR MEDICINE