Article
Chemistry, Multidisciplinary
Kazim K. Moncal, Hemanth Gudapati, Kevin P. Godzik, Dong N. Heo, Youngnam Kang, Elias Rizk, Dino J. Ravnic, Hwabok Wee, David F. Pepley, Veli Ozbolat, Gregory S. Lewis, Jason Z. Moore, Ryan R. Driskell, Thomas D. Samson, Ibrahim T. Ozbolat
Summary: The study demonstrates the intra-operative bioprinting of various craniomaxillofacial tissues directly on rats, including bone, skin, and composite tissues. A novel osteogenic hard tissue ink and droplet-based bioprinting technology facilitated substantial bone regeneration and accelerated wound closure in a stratified arrangement. The use of a hybrid approach resulted in significant skin wound closure and bone coverage, showcasing the potential for bioprinting technologies in clinical CMF defect reconstruction.
ADVANCED FUNCTIONAL MATERIALS
(2021)
Review
Chemistry, Multidisciplinary
Jie Cui, Xiao Yu, Yihong Shen, Binbin Sun, Wanxin Guo, Mingyue Liu, Yujie Chen, Li Wang, Xingping Zhou, Muhammad Shafiq, Xiumei Mo
Summary: Tissue engineering has gained widespread attention as a method of producing patient-specific tissue constructs for tissue repair. Different types of scaffold materials have been developed, and the choice of materials should consider their mechanical properties, biodegradability, biocompatibility, and bioresorbability. Inorganic materials, with their broad range of physico-chemical properties, can be used as scaffold fillers and offer a good alternative for tissue engineering. This review focuses on the use of inorganic components in electrospun membranes and emphasizes the biological advantages of incorporating inorganic materials in tissue repair.
Article
Materials Science, Multidisciplinary
Pedram Iranmanesh, Mohammad Gowdini, Abbasali Khademi, Mohammad Dehghani, Mehran Latifi, Naif Alsaadi, Mehran Hemati, Ramin Mohammadi, Saeed Saber-Samandari, Davood Toghraie, Afrasyab Khan
Summary: The combination of 3D bioprinting technology with novel hydrogel and bioink has led to the successful fabrication of scaffolds with unique mechanical and biological responses. The addition of naproxen coating enhances the tensile strength of the scaffolds, showing promising compatibility with the human body.
JOURNAL OF MATERIALS RESEARCH AND TECHNOLOGY-JMR&T
(2021)
Article
Biochemistry & Molecular Biology
Anuj Kumar, So-Yeon Won, Ankur Sood, So-Yeon Choi, Ritu Singhmar, Rakesh Bhaskar, Vineet Kumar, Sun Mi Zo, Sung-Soo Han
Summary: Hydrogel is a polymeric network that can swell in water and has been widely used in biomedical applications. However, its low mechanical properties limit its application in functional tissues. The incorporation of dual-crosslinking and nanofillers can enhance the mechanical properties of hydrogels.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Mathematics, Applied
Andrzej Okolewski, Barbara Blazejczyk-Okolewska
Summary: The study reconsiders the application of soft and hard impact models in vibro-impact systems, discussing conditions for energy dissipation equivalence and demonstrating key features of soft impact models. The effects of additional elastic-damping elements and external forcing on system behavior are examined, showing different results based on the stiffness and energy dissipation rate of the base when applying the soft impact model.
Article
Polymer Science
Ehsan Fallahiarezoudar, Nor Hasrul Akhmal Ngadiman, Noordin Mohd Yusof, Ani Idris, Mohamad Shaiful Ashrul Ishak
Summary: The study developed a three-dimensional scaffold for soft tissue engineering using digital light processing and ultra-hard and tough bio-resin. The mechanical properties and biocompatibility of the scaffold were evaluated, and it was found that the structure with 15% wt/v TPU/UHT and 1% gamma-Fe2O3 had the highest Young's Modulus. The scaffold containing gamma-Fe2O3 had a higher degradation rate but improved cell proliferation rate.
Review
Dentistry, Oral Surgery & Medicine
Matthias Widbiller, Gottfried Schmalz
Summary: Different organisms and living things react differently to the loss of organs or tissue damage. While some can completely regenerate lost body parts, others react by forming scars for tissue repair. The regenerative capacities of the human body are limited, with only a few tissues fully restored when injured.
Review
Biochemistry & Molecular Biology
Le Yu, Mei Wei
Summary: This review discusses the mineralization of collagen fibrils into hydroxyapatite, dividing it into intrafibrillar and extrafibrillar mineralization. Various mechanisms and strategies for inducing biomimetic intrafibrillar mineralization are examined, along with applications for bone regeneration and dentin repair using mineralized collagen fibers. Potential future trends in collagen-based materials for bone and tooth repair are also speculated.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Review
Chemistry, Analytical
Felicia Carotenuto, Sara Politi, Arsalan Ul Haq, Fabio De Matteis, Emanuela Tamburri, Maria Letizia Terranova, Laura Teodori, Alessandra Pasquo, Paolo Di Nardo
Summary: The failure of tissues and organs due to degenerative diseases or trauma is a major concern globally. Tissue engineering offers a potential solution by regenerating or replacing damaged tissues and organs. Biomaterials play a crucial role in promoting new tissue formation, with their architectural features influencing cellular behaviors. Optimizing the micro/nano architecture of biomaterials is essential for successful regenerative therapy. Various micro/nanostructured biomaterials have been developed to mimic the structure of different soft and hard tissues, with a focus on muscle, cartilage, and bone tissue regeneration.
Review
Chemistry, Physical
Lakshmipathy Muthukrishnan
Summary: This review provides an overview of electrospinning, including its principle, methods, feed materials, and applications in tissue engineering. It highlights the rapid development of nanofiber technology and the potential demand for tissue engineering applications.
COLLOID AND POLYMER SCIENCE
(2022)
Review
Materials Science, Multidisciplinary
Anna Doersam, Olga Tsigkou, Celina Jones
Summary: In cell-free scaffold tissue engineering, the design of the scaffold plays a crucial role in promoting cellular activities and tissue formation. Textile technologies offer biomimetic and functional scaffold designs similar to the extracellular matrix (ECM), with precise size-to-scale design and manufacturing precision. However, current fibrous scaffold designs fail to fully exploit the potential and diversity of yarn and fabric structures. The review emphasizes the use of hollow tubular textile-based scaffolds to replace vasculature and respiratory tissues, discussing techniques such as electrospinning, weaving, knitting, and braiding, and highlighting the impact of fiber, yarn, and fabric assembly.
ADVANCED MATERIALS TECHNOLOGIES
(2022)
Article
Materials Science, Biomaterials
Fahimeh Tabatabaei, Morteza Rasoulianboroujeni, Amir Yadegari, Sanaz Tajik, Keyvan Moharamzadeh, Lobat Tayebi
Summary: This study introduces a novel approach to combine tissue-engineered human bone with oral mucosa, aiming to improve cell growth and tissue integration. Results indicate that the new method of adhesion leads to better biological outcomes compared to traditional methods.
MATERIALS SCIENCE AND ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS
(2021)
Review
Biotechnology & Applied Microbiology
Liwei Duan, Zongliang Wang, Shuang Fan, Chen Wang, Yi Zhang
Summary: In recent decades, there has been substantial interest in bioactive and biomimetic biomaterials for reconstructing urinary tissues. Innovative technologies have also emerged in urinary tissue engineering, enabling the reproduction of hierarchical structures and tissue functions of the bladder, urethra, and ureter. Nanofibrous biomaterials derived from natural tissues, synthetic biopolymers, and hybrid scaffolds, as well as growth factors and inorganic nanomaterials, have been developed to enhance the functionality of scaffolds. Advanced approaches like 3D printing and organoids have been utilized to facilitate structural and functional regeneration of the urological system.
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
(2023)
Review
Biochemistry & Molecular Biology
Sven Pantermehl, Steffen Emmert, Aenne Foth, Niels Grabow, Said Alkildani, Rainer Bader, Mike Barbeck, Ole Jung
Summary: The use of additive manufacturing technology in modern medicine is a relatively new field, offering fast and effective ways to produce personalized implants, tissues, and organs for patients. This review provides an overview of various 3D printing technologies, discussing their functions, strengths, and weaknesses in medical applications, as well as summarizing previous studies in tissue engineering.
Article
Materials Science, Multidisciplinary
Xinwen Zhang, Ruoyun Wang, Fei Long, Tong Zhou, Wenbin Hu, Lei Liu
Summary: The study fabricated a durable superhydrophobic coating on aluminum alloy using hard-soft technology, leading to excellent hydrophobicity and durability. Even after extensive polishing, the hydrophobic property of the coating can be restored after heat treatment, significantly improving its corrosion resistance.
Article
Health Care Sciences & Services
Jelle L. P. van Gurp, Anne Ebenau, Simone van der Burg, Jeroen Hasselaar
BMC PALLIATIVE CARE
(2020)
Article
Public, Environmental & Occupational Health
Anke J. M. Oerlemans, Marjan L. Knippenberg, Gert J. Olthuis
Summary: Learning shared decision-making (SDM) in clinical practice involves observing and imitating other professionals, as well as reflecting on personal experiences. Both patients and professionals agree that learning the nuances of SDM is a complex task that requires involvement of patients, informal learning processes, and role models.
PATIENT EDUCATION AND COUNSELING
(2021)
Article
Biochemistry & Molecular Biology
Vyne van der Schoot, Simone J. Viellevoije, Femke Tammer, Han G. Brunner, Yvonne Arens, Helger G. Yntema, Anke J. M. Oerlemans
Summary: The impact of disclosing unsolicited findings (UFs) in clinical exome sequencing on patients includes psychological, physical, and financial aspects. Factors influencing this impact include actionability, understanding, patients' pre-test health, and social context. Despite initial psychological impact, most patients would choose to undergo genetic testing again.
EUROPEAN JOURNAL OF HUMAN GENETICS
(2021)
Article
Obstetrics & Gynecology
Laura A. M. van Lieshout, Malou E. Gelderblom, Joanne A. de Hullu, Regina The, Alexandra A. van Ginkel, Anke J. M. Oerlemans, Kirsten M. W. H. Smeets, Malou P. H. Schreurs, Jurgen M. J. Piek, Rosella P. M. G. Hermens
Summary: A patient decision aid was developed in collaboration with patients and healthcare professionals for opportunistic salpingectomy and salpingectomy as a sterilization method. The tool was found to be useful in supporting patients in making informed decisions and supporting the counseling process by gynecologists.
AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY
(2022)
Article
Pediatrics
Heleen van Engelen, Jose A. E. Custers, Barbara M. Kortmann, Anke J. M. Oerlemans, Iris A. L. M. van Rooij, Chris M. Verhaak
Summary: This study examines the factors contributing to parental decisional regret after surgery for hypospadias in young boys. The results indicate that decisional conflict and psychosocial behavior problems in the child significantly predict decisional regret, while demographic and medical variables do not correlate with parental regret. Future research should focus on the interrelationship between medical and psychosocial factors in decision-making processes surrounding this surgery.
JOURNAL OF PEDIATRIC UROLOGY
(2021)
Article
Biochemistry & Molecular Biology
Vyne Van der Schoot, Lonneke Haer-Wigman, Ilse Feenstra, Femke Tammer, Anke J. M. Oerlemans, Martine P. A. van Koolwijk, Frans van Agt, Yvonne H. J. M. Arens, Han G. Brunner, Lisenka E. L. M. Vissers, Helger G. Yntema
Summary: Unsolicited findings (UFs) are unintentionally discovered and predispose to diseases unrelated to the clinical question. The frequency of UFs in clinical whole-exome sequencing is low, with fewer UFs identified using restricted disease-gene panels compared to whole-exome/Mendeliome analysis.
EUROPEAN JOURNAL OF HUMAN GENETICS
(2022)
Article
Computer Science, Artificial Intelligence
Simone van der Burg, Else Giesbers, Marc-Jeroen Bogaardt, Wijbrand Ouweltjes, Kees Lokhorst
Summary: In recent years, the development of AI robots for agriculture, livestock farming and food processing industries has rapidly increased. However, these robots also raise societal and ethical questions. This article explores the values and ethical questions surrounding four types of AI robots in the agri-food sector through case studies, finding that stakeholders primarily adopt a relational perspective and prioritize finding solutions to these ethical questions. The results suggest that the best approach in the agri-food sector is to distribute tasks between human beings and robots to achieve the most acceptable, good or just collaboration that contributes to societal goals and addresses the challenges of the 21st century.
Article
Endocrinology & Metabolism
Sanne van der Coelen, Janielle van der Velden, Sapthami Nadesapillai, Ron Peek, Didi Braat, Myra Schleedoorn, Kathrin Fleischer, Anke Oerlemans
Summary: The study aimed to gain insight into the experiences of patients, parents, and healthcare providers with the decision-making process regarding ovarian tissue cryopreservation (OTC) in girls with Turner syndrome (TS). The results showed that 90% of the respondents appreciated counseling regarding their future parenting options and considered OTC an addition to existing healthcare. Girls with TS and their parents felt that OTC raised hope for future genetic offspring and made them feel that their only option was to seize this opportunity.
HORMONE RESEARCH IN PAEDIATRICS
(2022)
Article
Genetics & Heredity
Vyne van der Schoot, Carlijn Damste, Helger G. Yntema, Han G. Brunner, Anke J. M. Oerlemans
Summary: This study explored clinical geneticists' views and experiences regarding discussion and disclosure of unsolicited findings (UFs) during pretest counseling. The results highlight the importance of tailored pretest counseling and informed consent for optimal genetic consultations. Furthermore, the study emphasizes the need for further understanding of what constitutes medical actionability, suggesting the installation of an expert panel to assist healthcare professionals in decision-making.
JOURNAL OF GENETIC COUNSELING
(2023)
Editorial Material
Ethics
Anke J. M. Oerlemans, Ilse Feenstra, Helger G. Yntema, Marianne Boenink
JOURNAL OF MEDICAL ETHICS
(2023)
Review
Rehabilitation
Roel van Oorsouw, Anke Oerlemans, Gijs van Oorsouw, Mark van den Boogaard, Philip van der Wees, Niek Koenders
Summary: Through a systematic literature search, this study synthesizes the lived body experiences of ICU patients during their stay and recovery. The findings indicate that patients experience a sense of powerlessness, empowerment, and permanent changes in their bodies during the recovery process.
PHYSIOTHERAPY THEORY AND PRACTICE
(2023)
Article
Public, Environmental & Occupational Health
Anke J. M. Oerlemans, Aletta G. Dorst, Marjan L. Knippenberg, Gert J. Olthuis
Summary: People with dementia from migrant and ethnic minority (MEM) groups often face suboptimal care due to differences in perceptions and linguistic barriers. This study found a lack of metaphorical language and a negative outlook on dementia among informal caregivers from diverse cultural backgrounds.
SSM-QUALITATIVE RESEARCH IN HEALTH
(2023)
Article
Social Issues
Marijke Naezer, Anke Oerlemans, Gijs Hablous, Hedi Claahsen-van der Grinten, Anna van der Vleuten, Chris Verhaak
Summary: Debates surrounding healthcare for intersex/DSD and transgender children and adolescents revolve around early interventions and 'cautious gatekeeping', with medical and psychological research offering valuable insights but remaining ethically complex due to intertwined gender norms and expectations.
JOURNAL OF GENDER STUDIES
(2021)
Article
Ethics
Simone van der Burg, Leanne Wiseman, Jovana Krkeljas
Summary: Digital farming technologies can improve the quality and quantity of agricultural production while reducing environmental impact, but only if farmers are willing to share their data with agribusinesses. In order to foster trust in data sharing, the EU has implemented a Code of Conduct for agricultural data sharing, highlighting the important role of contracts in building trust relationships.
ETHICS AND INFORMATION TECHNOLOGY
(2021)
Article
Multidisciplinary Sciences
Anne C. de Munter, Wilhelmina L. M. Ruijs, Robert A. C. Ruiter, Dagmar J. J. van Nimwegen, Anke J. M. Oerlemans, Rijk van Ginkel, Marlies E. J. L. Hulscher, Jeannine L. A. Hautvast