Response to Comment on Innovative scattering analysis shows that hydrophobic disordered proteins are expanded in water

Best et al. claim that we provide no convincing basis to assert that a discrepancy remains between FRETand SAXS results on the dimensions of disordered proteins under physiological conditions. We maintain that a clear discrepancy is apparent in our and other recent publications, including results shown in the Best et al. comment. A plausible origin is fluorophore interactions in FRET experiments.