Epistasis Among Adaptive Mutations in Deer Mouse Hemoglobin

Deer mouse hemoglobin exhibits a lowered oxygen affinity owing to mobility of the E helix

(2013) Noriko Inoguchi et al.   Acta Crystallographica Section F-Structural Biology and Crystallization Communications

Phenotypic plasticity in blood-oxygen transport in highland and lowland deer mice

(2012) D. M. Tufts et al.   JOURNAL OF EXPERIMENTAL BIOLOGY

Altitudinal Variation at Duplicated β-Globin Genes in Deer Mice: Effects of Selection, Recombination, and Gene Conversion

(2011) Jay F. Storz et al.   GENETICS

Expression and Purification of Recombinant Hemoglobin in Escherichia coli

(2011) Chandrasekhar Natarajan et al.   PLoS One

Molecular mechanisms of epistasis within and between genes

(2011) Ben Lehner   TRENDS IN GENETICS

Reciprocal Sign Epistasis between Frequently Experimentally Evolved Adaptive Mutations Causes a Rugged Fitness Landscape

(2011) Daniel J. Kvitek et al.   PLoS Genetics

Epistasis between Beneficial Mutations and the Phenotype-to-Fitness Map for a ssDNA Virus

(2011) Darin R. Rokyta et al.   PLoS Genetics

Initial Mutations Direct Alternative Pathways of Protein Evolution

(2011) Merijn L. M. Salverda et al.   PLoS Genetics

Fitness Epistasis and Constraints on Adaptation in a Human Immunodeficiency Virus Type 1 Protein Region

(2010) J. da Silva et al.   GENETICS

Genetic differences in hemoglobin function between highland and lowland deer mice

(2010) J. F. Storz et al.   JOURNAL OF EXPERIMENTAL BIOLOGY

Pervasive Cryptic Epistasis in Molecular Evolution

(2010) Mark Lunzer et al.   PLoS Genetics

An epistatic ratchet constrains the direction of glucocorticoid receptor evolution

(2009) Jamie T. Bridgham et al.   NATURE

Stepwise acquisition of pyrimethamine resistance in the malaria parasite

(2009) E. R. Lozovsky et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Evolutionary and functional insights into the mechanism underlying high-altitude adaptation of deer mouse hemoglobin

(2009) J. F. Storz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Effects of Spatially Varying Selection on Nucleotide Diversity and Linkage Disequilibrium: Insights From Deer Mouse Globin Genes

(2008) J. F. Storz et al.   GENETICS

Epistasis — the essential role of gene interactions in the structure and evolution of genetic systems

(2008) Patrick C. Phillips   NATURE REVIEWS GENETICS