Crystal Structure of the Human Two-Pore Domain Potassium Channel K2P1

Overview of theCCP4 suite and current developments

(2011) Martyn D. Winn et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

The pore structure and gating mechanism of K2P channels

(2011) Paula L Piechotta et al.   EMBO JOURNAL

The crystal structure of a voltage-gated sodium channel

(2011) Jian Payandeh et al.   NATURE

Optical probing of a dynamic membrane interaction that regulates the TREK1 channel

(2011) G. Sandoz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

TWIK-1 Two-Pore Domain Potassium Channels Change Ion Selectivity and Conduct Inward Leak Sodium Currents in Hypokalemia

(2011) L. Ma et al.   Science Signaling

PHENIX: a comprehensive Python-based system for macromolecular structure solution

(2010) Paul D. Adams et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Novel insights into K+ selectivity from high-resolution structures of an open K+ channel pore

(2010) Sheng Ye et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Molecular Background of Leak K+ Currents: Two-Pore Domain Potassium Channels

(2010) Péter Enyedi et al.   PHYSIOLOGICAL REVIEWS

One SUMO is sufficient to silence the dimeric potassium channel K2P1

(2010) L. D. Plant et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structure of a Eukaryotic CLC Transporter Defines an Intermediate State in the Transport Cycle

(2010) Liang Feng et al.   SCIENCE

MolProbity: all-atom structure validation for macromolecular crystallography

(2009) Vincent B. Chen et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Potassium Channel Silencing by Constitutive Endocytosis and Intracellular Sequestration

(2009) Sylvain Feliciangeli et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Functional Reconstitution of Purified Human Hv1 H+ Channels

(2009) Seok-Yong Lee et al.   JOURNAL OF MOLECULAR BIOLOGY

TWIK-1 and TREK-1 Are Potassium Channels Contributing Significantly to Astrocyte Passive Conductance in Rat Hippocampal Slices

(2009) M. Zhou et al.   JOURNAL OF NEUROSCIENCE

The response of the tandem pore potassium channel TASK-3 (K2P9.1) to voltage: gating at the cytoplasmic mouth

(2009) I. Ashmole et al.   JOURNAL OF PHYSIOLOGY-LONDON

Crystal Structure of the Eukaryotic Strong Inward-Rectifier K+ Channel Kir2.2 at 3.1 A Resolution

(2009) X. Tao et al.   SCIENCE

The mechano-gated K2P channel TREK-1

(2008) Alexandra Dedman et al.   EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS

The M1P1 Loop of TASK3 K2P Channels Apposes the Selectivity Filter and Influences Channel Function

(2008) Catherine E. Clarke et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Inverse coupling in leak and voltage-activated K+ channel gates underlies distinct roles in electrical signaling

(2008) Yuval Ben-Abu et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY