Review
Health Care Sciences & Services
Nachiket Gudi, Prashanthi Kamath, Trishnika Chakraborty, Anil G. Jacob, Shradha S. Parsekar, Suptendra Nath Sarbadhikari, Oommen John
Summary: Although there is recognition of the scientific value of data sharing from clinical trials, there are various limitations and challenges in implementing data sharing practices. This review highlights the need for a pragmatic data-sharing mechanism to improve research and innovations, and calls for the development of flexible yet comprehensive data-sharing policies. It also emphasizes the importance of institutional mechanisms and policy interventions in facilitating data sharing, particularly in low- and middle-income countries.
JOURNAL OF MEDICAL INTERNET RESEARCH
(2022)
Article
Health Care Sciences & Services
Louis Dron, Alison Dillman, Michael J. Zoratti, Jonas Haggstrom, Edward J. Mills, Jay J. H. Park
Summary: During the COVID-19 pandemic, a large number of clinical trials have been conducted with many ending early due to feasibility issues, leading to inconclusive findings and potential false positives and negatives amidst a lack of common data standards for pooling results.
JOURNAL OF MEDICAL INTERNET RESEARCH
(2021)
Article
Economics
Takahiro Ishii
Summary: This study theoretically examines the effects of free technology sharing by a monopolistic firm with other firms in the market. Two cases are considered: one with one firm in the market and another with two firms in the market. The results show that when another firm enters the final goods market and transforms it into an oligopoly, cost efficiency improves due to an increase in the number of intermediate goods firms. It is also found that the incumbent firm's profits can increase even in oligopolies with three or more firms.
Review
Biochemical Research Methods
Claude Pellen, Anne Le Louarn, Gilliosa Spurrier-Bernard, Evelyne Decullier, Jean-Marie Chretien, Eric Rosenthal, Gerard Le Goff, David Moher, John P. A. Ioannidis, Florian Naudet
Summary: Clinical trial data-sharing is crucial for research integrity. However, early experiences have been unsatisfactory because of improper conduct. We propose 10 rules for researchers to follow, including abiding by legal requirements, involving research participants, determining data access methods, and striving for excellence.
PLOS COMPUTATIONAL BIOLOGY
(2023)
Article
Economics
Dominique Lepore, Sabrina Dubbini, Alessandra Micozzi, Francesca Spigarelli
Summary: The study highlights the importance of collaboration in introducing Industry 4.0 technologies, showing how firms play a mentoring role in supporting others and fostering a collaborative culture regionally. Both formal and informal collaborative approaches within organizations are found to support the adoption of new digital technologies.
JOURNAL OF THE KNOWLEDGE ECONOMY
(2022)
Article
Computer Science, Information Systems
P. Anitha, Srimathi Chandrasekaran
Summary: This study proposes a novel method called Supersingular Isogeny and Hosmer-Lemeshow Logistic Regression-based (SI-HLLR) to secure information sharing in the pharmaceutical supply chain. By implementing blockchain and a validation mechanism, this method can address the issue of counterfeit drugs entering the supply chain.
Review
Pharmacology & Pharmacy
Leo Pio-Lopez, Michael Levin
Summary: Morphoceuticals is a novel intervention that controls growth and form by targeting the setpoints of anatomical homeostasis. In this subclass, called electroceuticals, the focus is on targeting the cellular bioelectrical interface. By manipulating the bioelectric signals, the control of embryogenesis, tissue regeneration, cancer suppression, and anti-aging therapeutics can be achieved.
DRUG DISCOVERY TODAY
(2023)
Article
Chemistry, Multidisciplinary
S. Panda, S. Hajra, A. Kaushik, H. G. Rubahn, Y. K. Mishra, H. J. Kim
Summary: This comprehensive review explores the potential of smart nanomaterials in cancer management, focusing on various types of nanomaterials and their applications in diagnostics, targeted drug delivery, and therapy. It critically analyzes recent studies and discusses challenges and prospects in the field, proposing a novel multidisciplinary and combinational approach for personalized cancer management.
MATERIALS TODAY CHEMISTRY
(2022)
Editorial Material
Multidisciplinary Sciences
Jeffrey M. Perkel
Summary: Specialists provide seven tips for effectively sharing data.
Editorial Material
Biochemistry & Molecular Biology
Ulrich Mansmann, Clara Locher, Fabian Prasser, Tracey Weissgerber, Ulrich Sax, Martin Posch, Evelyne Decullier, Ioana A. A. Cristea, Thomas P. A. Debray, Leonhard Held, David Moher, John P. A. Ioannidis, Joseph S. S. Ross, Christian Ohmann, Florian Naudet
Summary: Data sharing improves the value of medical research and promotes trust in clinical trials, but more biomedical researchers need training in approaches such as meta-research, data science, and ethical, legal, and social issues.
Article
Business
Joern Hoppmann, Geng Wu, Jillian Johnson
Summary: The way firms search for knowledge has a critical impact on their innovation performance and technological evolution, and public policies can influence these search activities. Technology-push policies increase search distance, demand-pull policies decrease it, and the influence of policies on search scope is moderated by the breadth of firms' existing knowledge base.
TECHNOLOGICAL FORECASTING AND SOCIAL CHANGE
(2021)
Article
Green & Sustainable Science & Technology
Ye-Chan Park, Paul Hong
Summary: The research findings suggest that knowledge-sharing practices have a positive impact on the corporate sustainability of sharing economy companies. However, in the short run, sustainability has a negative effect on financial performance, but it has a positive impact in the long run. This study provides valuable insights into how sharing economy firms achieve their sustainability goals and offers implications for managerial practices. Future research can explore additional related issues.
Article
Biotechnology & Applied Microbiology
Zdenka Dudova, Nathalie Conte, Jeremy Mason, Dalibor Stuchlik, Radim Pesa, Csaba Halmagyi, Zinaida Perova, Abayomi Mosaku, Ross Thorne, Alex Follette, Luboslav Pivarc, Radim Sasinka, Muhammad Usman, Steven Neuhauser, Dale A. Begley, Debra M. Krupke, Massimiliano Frassa, Alessandro Fiori, Riccardo Corsi, Luca Vezzadini, Claudio Isella, Andrea Bertotti, Carol Bult, Helen Parkinson, Enzo Medico, Terrence Meehan, Ales Krenek
Summary: This article introduces the EurOPDX Data Portal, a unified platform that combines the European model catalog and molecular data analysis function. The Portal provides researchers with collaborative research PDX mice models and displays the molecular features and treatment research data of these models.
Article
Computer Science, Information Systems
Yalan Chen, Chunjiang Yu, Xingyun Liu, Ting Xi, Guangfei Xu, Yan Sun, Fei Zhu, Bairong Shen
Summary: Through the construction of PCLiON, 397 lifestyles and lifestyle-related factors associated with prostate cancer have been successfully integrated, establishing a standardized lifestyle ontology. This can promote shared decision-making on lifestyle intervention and assist patients in lifestyle self-management.
INTERNATIONAL JOURNAL OF MEDICAL INFORMATICS
(2021)
Article
Oncology
Clay McLeod, Alexander M. Gout, Xin Zhou, Andrew Thrasher, Delaram Rahbarinia, Samuel W. Brady, Michael Macias, Kirby Birch, David Finkelstein, Jobin Sunny, Rahul Mudunuri, Brent A. Orr, Madison Treadway, Bob Davidson, Tracy K. Ard, Arthur Chiao, Andrew Swistak, Stephanie Wiggins, Scott Foy, Jian Wang, Edgar Sioson, Shuoguo Wang, J. Robert Michael, Yu Liu, Xiaotu Ma, Aman Patel, Michael N. Edmonson, Mark R. Wilkinson, Andrew M. Frantz, Ti-Cheng Chang, Liqing Tian, Shaohua Lei, S. M. Ashiqul Islam, Christopher Meyer, Naina Thangaraj, Pamella Tater, Vijay Kandali, Singer Ma, Tuan Nguyen, Omar Serang, Irina McGuire, Nedra Robison, Darrell Gentry, Xing Tang, Lance E. Palmer, Gang Wu, Ed Suh, Leigh Tanner, James McMurry, Matthew Lear, Alberto S. Pappo, Zhaoming Wang, Carmen L. Wilson, Yong Cheng, Soheil Meshinchi, Ludmil B. Alexandrov, Mitchell J. Weiss, Gregory T. Armstrong, Leslie L. Robison, Yutaka Yasui, Kim E. Nichols, David W. Ellison, Chaitanya Bangur, Charles G. Mullighan, Suzanne J. Baker, Michael A. Dyer, Geralyn Miller, Scott Newman, Michael Rusch, Richard Daly, Keith Perry, James R. Downing, Jinghui Zhang
Summary: Effective data sharing is crucial in accelerating research and improving diagnostic precision, treatment efficacy, and long-term survival rates for pediatric cancer. St. Jude Cloud provides a cloud-based ecosystem with over 1.2 petabytes of genomic data from over 10,000 pediatric patients, enabling advanced data analysis and knowledge enhancement in pediatric cancer research.