Editorial Material
Biochemistry & Molecular Biology
Laurie H. Glimcher, Gregory A. Petsko
Summary: Professor Yuk Ming Dennis Lo of the Chinese University of Hong Kong is awarded the 2022 Lasker-DeBakey Clinical Medical Research Award for his discovery of fetal DNA in maternal blood, leading to the development of noninvasive prenatal testing for Down syndrome.
Article
Education, Scientific Disciplines
Eric S. Holmboe, Jennifer R. Kogan
Summary: This article discusses the issue of unwarranted variation in medical education. The authors argue that while some variability is acceptable, unwarranted variation has a negative impact on educational outcomes and healthcare quality. To address this issue, medical educators need to differentiate between warranted and unwarranted variation and implement continuous quality improvement measures.
Editorial Material
Oncology
Ana C. Veneziani, Amit M. Oza
Summary: Targeted therapy for low-grade serous ovarian carcinomas is still an unmet need, but recent advances in molecular characterization have widened the scope for novel targeted therapies.
CLINICAL CANCER RESEARCH
(2022)
Article
Biochemistry & Molecular Biology
Lizabeth A. Allison
Summary: The author originally intended to write a detailed review of the contributions of scientists in the nuclear receptor research field but was compelled to switch focus to a more personal story due to the current challenging environment, highlighting her journey as a woman in STEM and an advocate for inclusivity. By sharing her reflections, she hopes to inspire young investigators to persist in their pursuit of a career in science.
JOURNAL OF BIOLOGICAL CHEMISTRY
(2021)
Article
Nutrition & Dietetics
Matteo Briguglio
Summary: Hydration practices for patients undergoing hip, knee, or spine surgery advise against consuming caffeinated drinks, alcoholic beverages, and sugar-sweetened drinks as they can disrupt body fluid balance. However, the author of this opinion article questions the inclusion of beer among prohibited beverages due to its low alcohol content and conflicting evidence on its rehydrating effects.
Article
Psychology, Experimental
Akshina Banerjee, Oleg Urminsky
Summary: Prior research has found that the way information is communicated can affect decision-making, especially the structure of language, particularly the form of verb tense, which can predict savings behavior among speakers of different languages. This study tests the causal effect of language structure on financial decision-making by manipulating verb tense within a single language. The findings show that verb tense can significantly influence choices due to temporal inferences. However, the spontaneous use of verb tense in decision-making only occurs when there are no other timing cues, and it is eliminated if there are ambiguous or non-diagnostic time cues present, although prompted timing inferences persist.
JOURNAL OF EXPERIMENTAL PSYCHOLOGY-GENERAL
(2022)
Article
Agronomy
Quinn Marshall, Alexandra L. Bellows, Rebecca McLaren, Andrew D. Jones, Jessica Fanzo
Summary: Studying food systems is complex due to diverse actors and interlinking processes. Descriptive research and comparisons across geography, income groups, and population groups are important foundations. Introducing data visualization tools can improve access to and usage of food systems-related data, influencing policies and actions more effectively.
Article
Neurosciences
Geza Gergely Ambrus, Charlotta Marina Eick, Daniel Kaiser, Gyula Kovacs
Summary: The study revealed that different qualities of familiarization have a profound impact on representations of face familiarity, with face familiarity representations being weaker after media familiarization compared to personal familiarization. There was no enhancement found in face identity representation across all experiments, indicating that familiarity and identity representations emerge independently during face familiarization. The results highlight the importance of extensive, real-life familiarization for the emergence of robust face familiarity representations, which constrains models of face perception and recognition memory.
JOURNAL OF NEUROSCIENCE
(2021)
Article
Chemistry, Organic
Hans-Jurgen Federsel
Summary: This short review discusses the importance of the Green Chemistry Principles in designing chemical processes, particularly in the pharmaceutical industry. It also explores the use of life-cycle assessment and metrics to measure the performance of chemical manufacturing.
SYNTHESIS-STUTTGART
(2022)
Article
Cell Biology
Juan S. Bonifacino
Summary: This passage describes the application of electron microscopy in studying eukaryotic cells and the importance of this development in understanding the internal organization and function of these cells. The author's long-term research focuses on protein sorting and organelle transport in the cytoplasm, and has revealed various mechanisms and defects leading to human diseases.
MOLECULAR BIOLOGY OF THE CELL
(2022)
Editorial Material
Cell Biology
Julian Stopp, Michael Sixt
Summary: Reading, interpreting, and crawling along chemotactic gradients is a challenging question in cell biology. In this study, Georgantzoglou et al. (2022. J. Cell. Biol.) use in vivo models to map the temporal sequence of neutrophil response to an acutely arising chemoattractant gradient.
JOURNAL OF CELL BIOLOGY
(2022)
Review
Behavioral Sciences
Madalena Esteves, Pedro Silva Moreira, Nuno Sousa, Hugo Leite-Almeida
Summary: Impulsivity is a multidimensional construct involving behavioral inhibition and decision making, with adaptive fast responses but also abnormal manifestations in pathological contexts. Tools for assessing impulsivity exist in both behavioral and self-reported measures, with different applications in humans and rodents.
FRONTIERS IN BEHAVIORAL NEUROSCIENCE
(2021)
Editorial Material
Hematology
Helong Zhao, Michael W. Deininger
Summary: In this study, it was revealed that mutant SETBP1 induces a MYC-driven transcriptional program that promotes leukemogenesis in CSF3R mutant leukemia. Execution of this program relies on lysine-specific demethylase 1 (LSD1), suggesting that combining inhibitors of JAK2 and LSD1 may be a potential treatment for chronic neutrophilic leukemia (CNL).
Editorial Material
Biochemistry & Molecular Biology
Inna S. Afonina, Eik Hoffmann
Summary: This special issue of The FEBS Journal covers various aspects and new developments in the field of "Infection and Immunity". It includes expert views on the role of different immune cell populations, the regulation of innate and adaptive immune responses, and novel concepts in host defense and inflammatory signaling. Many reviews in this issue also highlight potential targets for future therapeutic interventions that aim to tackle inflammatory and immune responses.
Article
Management
YoungSoo Park, Jeongeun Sim, Bosung Kim
Summary: This paper addresses the decision-making problem of the Try-Before-You-Buy (TBYB) retailer in maximizing its profit by sending the optimum quantity of items to consumers based on a recommendation system. The study shows that recommendation accuracy and new consumer influx play significant roles in determining the optimal quantity decision and profit of the retailer.
EUROPEAN JOURNAL OF OPERATIONAL RESEARCH
(2022)
