Article
Chemistry, Analytical
Ji Sun Park, Sun-Ki Kim, Chang-Hyung Choi, Jong Pil Park, Kyeongsoon Park
Summary: The overproduction of hydrogen peroxide (H2O2) is closely associated with the progression of various diseases, making it an important diagnostic marker for in vivo molecular imaging. A novel Co2+-doped L012/magnesium peroxide-based chemiluminescence (CL) nanosystem (L-012/Co@MgO2) has been developed for visual detection and quantitative analysis of H2O2, which has potential applications in biosensing and bioimaging of H2O2.
SENSORS AND ACTUATORS B-CHEMICAL
(2023)
Article
Nanoscience & Nanotechnology
Baoji Miao, Muhammad Arsalan, Amal BaQais, Vignesh Murugadoss, Imran Saddique, Mohammed A. Amin, Junna Ren, Azka Awais, Qingsong Zhu, Ben Bin Xu, Fengchun Wei
Summary: The tetrametallic PtNiCuCo alloy nanoparticles were prepared and deposited on FTO substrates as a catalyst for highly sensitive H2O2 sensing. The PtNiCuCo nanoparticles had an average particle size of 5 +/- 1 nm. They showed excellent electro-oxidation activity for H2O2 with a wide linear range and low detection limit.
ADVANCED COMPOSITES AND HYBRID MATERIALS
(2023)
Review
Chemistry, Analytical
Ana Morais, Patricia Rijo, Belen Batanero, Marisa Nicolai
Summary: The commercial viability of electrochemical sensors relies on highly efficient electrode materials with high catalytic activity. Understanding the fundamental structures and typical catalytic properties of nanocatalysts is crucial for selecting the most efficient material. Transition metal nanoparticles have gained attention due to their high surface-to-volume ratio, higher electron transfer rate, and simple functionalization process.
Article
Biochemistry & Molecular Biology
M. Ramesh, C. Sankar, S. Umamatheswari, J. Balamurugan, R. Jayavel, M. Gowran
Summary: Pure ZnZrO2 and chitosan supported (ZnZrO2/CS) nanocomposite were synthesized via hydrothermal method. The structural and morphological properties of the fabricated nanocomposites were analyzed using various characterization techniques. The ZnZrO2/CS sensor showed wide detection range, high sensitivity, low LOD, and long-term stability for glucose detection in alkaline solution. It also exhibited excellent sensing ability towards hydrogen peroxide with wide dynamic range, high sensitivity, and low LOD. The modified electrode showed excellent anti-interference nature and was successfully used for glucose and H2O2 detection in human blood serum and HeLa cells.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Article
Chemistry, Analytical
Shaoqing Lu, Yongxian Guo, Lubin Qi, Qiongzheng Hu, Li Yu
Summary: A H2O2-responsive liquid crystal sensing platform was developed and utilized for detecting catalase in human serum, showing high sensitivity and label-free detection capabilities.
SENSORS AND ACTUATORS B-CHEMICAL
(2021)
Article
Chemistry, Analytical
Caixiu Luo, Xiaohong Liu, Fuxin Liu, Nan He, Rong Yu, Xiuhui Liu
Summary: A non-enzymatic sensor based on AgNPs/CNF materials was developed, showing excellent catalytic performance and ultra-low detection limit for H2O2 detection. The sensor demonstrated effective detection of H2O2 in actual disinfectant and human serum samples.
JOURNAL OF ELECTROANALYTICAL CHEMISTRY
(2022)
Article
Chemistry, Analytical
Cuicui Fu, Yuqiu Wang, Xue Tian, Yan Wu, Haiyan Cao, Yangyang Li, Young Mee Jung
Summary: A new SERS biosensor based on TSA was designed for highly sensitive detection of H2O2. The sensor utilizes HRP and TSA to catalyze the oxidation of OPD for quantitatively analyzing H2O2, showing a low detection limit and high sensitivity.
Article
Chemistry, Multidisciplinary
Yaqiong Kong, Rong Wu, Xiaodong Wang, Guoxu Qin, Fengyi Wu, Chunyu Wang, Minmin Chen, Nannan Wang, Qian Wang, Duojun Cao
Summary: It is of great significance to detect and image peroxynitrite (ONOO-) in vitro and in vivo with high selectivity and sensitivity. In this study, two simple benzothiazole-based fluorescent chemosensors, BS1 and BS2, were reported. Both probes could quickly sense ONOO- under physiological pH and showed a remarkable turn-on fluorescence signal. BS1, with a diphenyl phosphonate unit, exhibited higher selectivity for ONOO- than BS2. Additionally, BS1 was successfully employed to detect and image ONOO- in HepG2 cells with lower cytotoxicity and pH-stability. Furthermore, BS1 was used to showcase drug-induced hepatotoxicity and evaluate the remediation effect of GSH, demonstrating its great potential for detecting ONOO-.
Article
Chemistry, Analytical
Tong Yang, Wenna Zhang, Jiashun Wu, Kristin Zhao, Sheng Liu, Yan Zhao
Summary: By combining CuS and Ni(OH)2 into double-shell structures, CuS@Ni(OH)2 double-shelled nanocages were successfully fabricated and applied for glucose detection. This double-shell structure exhibits superior electrocatalytic performance and ideal detection limit, showing great potential in analytical sensing.
JOURNAL OF ELECTROANALYTICAL CHEMISTRY
(2022)
Article
Chemistry, Physical
Li-Fan Hsu, Karthic Natarajan, Chelladurai Karuppiah, Chun-Chen Yang
Summary: In this study, a novel enzyme-free hydrogen peroxide sensor electrode based on silver nanoparticles decorated polydopamine/sulfur-doped graphitic carbon nano-composite was developed. The sensor exhibited outstanding sensing ability with rapid response, high sensitivity, wide detection range, and low limit of detection. The practicality of the sensor was confirmed through testing commercial milk and mouthwash samples.
COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
(2023)
Article
Chemistry, Analytical
Hao Yin, YaHao Shi, YongPing Dong, XiangFeng Chu
Summary: CuGa2O4 nanoparticles were synthesized using hydrothermal-calcination technique and exhibited significant electrocatalytic effects for the reduction of H2O2 and oxidation of glucose. Under optimal conditions, sensitive detection of H2O2 and glucose was achieved, showing linear changes in concentration with electrochemical signals. This promising nanoparticle could improve non-enzymatic glucose sensors.
JOURNAL OF ELECTROANALYTICAL CHEMISTRY
(2021)
Article
Nanoscience & Nanotechnology
Xiaoqing Ma, Kang-lai Tang, Kang Lu, Chenke Zhang, Wenbing Shi, Wenxi Zhao
Summary: The research explores the use of hollow microflower-like CuS@C hybrids as a versatile electrochemical sensing platform for H2O2 reduction and N2H4 oxidation, demonstrating wide linear range and low detection limit. Elaborate strategies were employed to achieve the desired performance, such as the perfect formation of hollow architecture and the introduction of polydopamine-derived carbon skeleton.
ACS APPLIED MATERIALS & INTERFACES
(2021)
Article
Chemistry, Medicinal
Yong-Feng Wei, Xuan Wang, Wen-Jing Shi, Ru Chen, Liyao Zheng, Zi-Zhou Wang, Kun Chen, Liqian Gao
Summary: Hydrogen peroxide plays vital roles in living organisms, and there is a need to develop better probes for its detection. A novel fluorescent probe has been designed with high selectivity and sensitivity, suitable for detecting the presence of H2O2 in aqueous solutions and living cells.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
(2021)
Article
Spectroscopy
Van-Dat Doan, Van-Cuong Nguyen, Thi-Lan-Huong Nguyen, Anh-Tien Nguyen, Thanh-Danh Nguyen
Summary: In this study, silver nanoparticles were synthesized from Gleditsia australis fruit extract and their peroxidase-like activity was investigated for the detection of H2O2, glucose, and ascorbic acid. The sensing system showed good sensitivity for detecting bioactive compounds in biological systems, providing a new platform for bioanalysis.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2022)
Article
Chemistry, Analytical
Ema Gricar, Kurt Kalcher, Bostjan Genorio, Mitja Kolar
Summary: Four different graphene-based nanomaterials were synthesized, characterized, and utilized as modifiers of carbon paste electrodes to develop a non-enzymatic amperometric hydrogen peroxide sensor for complex matrices. The optimized sensor exhibited a wide linear range, excellent detection limit, and high stability, making it suitable for real sample analysis in pharmaceutical and saliva matrices. The recovery values for commercial pharmaceutical products and saliva samples demonstrated the accuracy and reliability of the sensor in practical applications.
