Editorial Material
Biology
Lawrence T. Reiter
Summary: Experiments on mice indicate that antisense oligonucleotide therapy, may be effective in treating certain symptoms of Angelman syndrome such as epilepsy and sleep disorders.
Article
Psychology, Multidisciplinary
Keiichi Kobayashi
Summary: This study found that different forms of scientific consensus messaging can impact participants' subsequent perceptions of scientific consensus, with heuristic and systematic processing impacting differently.
CURRENT PSYCHOLOGY
(2022)
Review
Endocrinology & Metabolism
A. B. Hansen, D. Wojdemann, C. H. Renault, A. T. Pedersen, K. M. Main, L. L. Raket, R. B. Jensen, A. Juul
Summary: This review covers the effects of sex steroids in adolescence, including scenarios of too little, too much, too late, and too early hormonal action. It discusses the etiology, signs and symptoms, differential diagnoses, long-term consequences, and treatment options for these hormonal disorders, as well as the use of exogenous sex steroids for therapeutic purposes in adolescents and young adults, such as gender-affirming therapy and hormone treatment for specific conditions.
EUROPEAN JOURNAL OF ENDOCRINOLOGY
(2021)
Review
Biochemistry & Molecular Biology
Jonathan Turpin, Daed El Safadi, Gregorie Lebeau, Morgane Krejbich, Camille Chatelain, Philippe Despres, Wildriss Viranaicken, Pascale Krejbich-Trotot
Summary: Cell death by apoptosis is a major cellular response in the control of tissue homeostasis and viral clearance. This study focuses on the interplay between Zika virus (ZIKV) infection and apoptosis in different cell types, and how the virus deals with this cellular response. The effects of ZIKV-controlled apoptosis are dual, depending on the timing and context, and understanding this interplay may have implications for ZIKV-related therapies and the use of ZIKV as an oncolytic agent.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Green & Sustainable Science & Technology
Magdalena Popowska, Aleksandra Sinkiewicz
Summary: This research analyzed the concept of sustainable fashion from the perspective of Polish consumers and found that they care more about the general environment but do not pay attention to sustainable development in the clothing industry. Additionally, compared to consumers in other countries, Poles have an unfavorable opinion of their own nation's approach to sustainable development in the garment industry.
Review
Clinical Neurology
Ruiqing Kang, Marcin Gamdzyk, Hong Tang, Yujie Luo, Cameron Lenahan, John H. Zhang
Summary: Stroke is the second leading cause of mortality worldwide, and the treatment of ischemic stroke typically involves thrombolytic therapy within 4.5 hours and thrombectomy within 6 hours. Many patients are unable to receive timely treatment, and alternative solutions are lacking for those who miss the optimal treatment window. Recent studies have shown that delayed recanalization may benefit some stroke patients, but the neuroprotective mechanisms underlying this phenomenon are still unclear.
TRANSLATIONAL STROKE RESEARCH
(2021)
Article
Multidisciplinary Sciences
Ruimin Wang, Bing Shen, Xianguo Lang, Bin Wen, Ross N. Mitchell, Haoran Ma, Zongjun Yin, Yongbo Peng, Yonggang Liu, Chuanming Zhou
Summary: A Great Ediacaran Glaciation, lasting for 20 million years, occurred globally from mid-to-high latitudes, witnessing the evolution of the Ediacara biota. The timing of Ediacaran glaciation remains controversial due to limited age constraints and a lack of convincing evidence for low-latitude glaciations. However, recent studies using carbon isotope excursions and paleomagnetic evidence suggest that the Ediacaran glaciation occurred diachronously but continuously from ca. 580-560 Ma as different continents migrated through polar-temperate latitudes.
NATIONAL SCIENCE REVIEW
(2023)
Article
Multidisciplinary Sciences
Nicholas Light, Philip M. Fernbach, Nathaniel Rabb, Mugur Geana, Steven A. Sloman
Summary: Public opposition to scientific consensus can have disastrous consequences, such as vaccine rejection and opposition to climate change mitigation policies. This study found that individuals who strongly oppose expert consensus on scientific issues tend to have low objective knowledge but high subjective knowledge. The implications of these findings for scientists, policymakers, and science communicators are discussed.
Article
Gastroenterology & Hepatology
Hayley Chen, Alexander Johnston, Andrew Palmer, Matthew Mickenbecker, Timothy O'Sullivan, Paul Clark
Summary: The study found that despite the benefits of timely palliative care referral, less than one quarter of patients with decompensated cirrhosis were referred. Referral seemed to be reserved for those facing imminent death, while mortality remained high for non-referred patients.
JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY
(2021)
Article
Business, Finance
Suzette Viviers, Lee-Ann Steenkamp
Summary: The study investigates the impact of macro-level antecedents on energy and environmental (E&E) shareholder activism in 12 developed countries. The findings show a slight increase in the number of shareholder-initiated E&E resolutions filed during the research period but with low voting support. Most resolutions focused on nuclear and environmental policies adoption or amendment, as well as improved E&E reporting. The study also reveals a significant relationship between the number of shareholder-initiated E&E resolutions filed and the rule of law.
SUSTAINABILITY ACCOUNTING MANAGEMENT AND POLICY JOURNAL
(2023)
Article
Oncology
Mark Marshall, Jennifer Ivanovich, Morgan Schmitt, Amy Helvie, Lisa Langsford, Jennifer Casterline, Michael Ferguson
Summary: Precision oncology involves selecting effective treatments for cancer patients based on genomic profiling of their tumors. While progress has been slower in pediatric oncology compared to adult oncology, advancements made in adult cancer treatments over the past decade are now being applied to young high-risk and hard-to-treat patients. The FDA has approved 23 targeted drugs for pediatric cancer, making them a standard of care.
FRONTIERS IN ONCOLOGY
(2023)
Article
Clinical Neurology
Anne Brink Behrndtz, Andreas Gammelgaard Damsbo, Rolf Ankerlund Blauenfeldt, Grethe Andersen, Lasse Ole Speiser, Claus Ziegler Simonsen
Summary: Despite effective treatments, many patients with acute ischemic stroke are not offered reperfusion therapy. The most common reason for non-treatment is presenting outside the treatment window. Our study suggests a benefit of thrombolysis for patients with mild symptoms.
FRONTIERS IN NEUROLOGY
(2022)
Article
Economics
Jonathan Guryan, Jens Ludwig, Monica P. Bhatt, Philip J. Cook, Jonathan M. V. Davis, Kenneth Dodge, George Farkas, Roland G. Fryer Jr, Susan Mayer, Harold Pollack, Laurence Steinberg, Greg Stoddard
Summary: Improving academic outcomes for economically disadvantaged students, especially at older ages, is challenging. Two large-scale randomized controlled trials in Chicago found that a high-dosage tutoring program using paraprofessional tutors increased math test scores and course grades in both math and nonmath subjects. These effects persisted over time, suggesting increased personalization of instruction as a mechanism. The benefit-cost ratio of the program is comparable to successful early childhood programs.
AMERICAN ECONOMIC REVIEW
(2023)
Article
Multidisciplinary Sciences
Erich K. Eberhard, David S. Wilcove, Andrew P. Dobson
Summary: This study examines the enduring puzzle of why there have been so few successfully recovered species under the U.S. Endangered Species Act, considered a model for global endangered species protection. The findings suggest that small population sizes at the time of listing, delayed protection, and insufficient funding continue to undermine the effectiveness of this law for biodiversity conservation.
Article
Neurosciences
Mei Gao, Xiaolan Yang, Linanzi Zhang, Qingguo Ma
Summary: The study revealed that the regret induced by stopping too late was stronger than stopping too early, leading subjects to prefer stopping earlier in such cases. This reflects a general pattern of human learning behavior. Gender differences and risk attitudes were also taken into consideration in the study.
FRONTIERS IN NEUROSCIENCE
(2021)
