Spirochromone-chalcone conjugates as antitubercular agents: synthesis, bio evaluation and molecular modeling studies

Pharmacophore and Docking Based Virtual Screening of Validated Mycobacterium tuberculosis Targets

(2015) Renu Vyas et al.   COMBINATORIAL CHEMISTRY & HIGH THROUGHPUT SCREENING

ChemScreener: A Distributed Computing Tool for Scaffold based Virtual Screening

(2015) Muthukumarasamy Karthikeyan et al.   COMBINATORIAL CHEMISTRY & HIGH THROUGHPUT SCREENING

4-Aminoquinoline-pyrimidine-aminoalkanols: synthesis, in vitro antimalarial activity, docking studies and ADME predictions

(2015) Mohit Tripathi et al.   NEW JOURNAL OF CHEMISTRY

Pharmacokinetic Modeling of Caco-2 Cell Permeability Using Genetic Programming (GP) Method

(2014) Renu Vyas et al.   Letters in Drug Design & Discovery

Synthesis and antitubercular activity of amino alcohol fused spirochromone conjugates

(2013) M. Mujahid et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Discovery of Mycobacterium tuberculosis Protein Tyrosine Phosphatase B (PtpB) Inhibitors from Natural Products

(2013) Alessandra Mascarello et al.   PLoS One

Mining collections of compounds with Screening Assistant 2

(2013) Vincent Guilloux et al.   Journal of Cheminformatics

lazar: a modular predictive toxicology framework

(2013) Andreas Maunz et al.   Frontiers in Pharmacology

Biology-Oriented Synthesis

(2011) Stefan Wetzel et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Synthesis, Biological Evaluation, And Molecular Modeling of Chalcone Derivatives As Potent Inhibitors of Mycobacterium tuberculosis Protein Tyrosine Phosphatases (PtpA and PtpB)

(2011) Louise Domeneghini Chiaradia et al.   JOURNAL OF MEDICINAL CHEMISTRY

The challenge of new drug discovery for tuberculosis

(2011) Anil Koul et al.   NATURE

Biology-oriented synthesis of a natural-product inspired oxepane collection yields a small-molecule activator of the Wnt-pathway

(2011) S. Basu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Syntheses and biological evaluation of new triazole-spirochromone conjugates as inhibitors of Mycobacterium tuberculosis

(2011) M. Muthukrishnan et al.   TETRAHEDRON LETTERS

Inhibition of Mycobacterium tuberculosis tyrosine phosphatase PtpA by synthetic chalcones: Kinetics, molecular modeling, toxicity and effect on growth

(2010) Alessandra Mascarello et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Fragment-based discovery of selective inhibitors of the Mycobacterium tuberculosis protein tyrosine phosphatase PtpA

(2009) Katherine A. Rawls et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Synthesis, antimalarial and antitubercular activity of acetylenic chalcones

(2009) Renate H. Hans et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

The first ionic liquid-promoted Kabbe condensation reaction for an expeditious synthesis of privileged bis-spirochromanone scaffolds

(2009) M. Muthukrishnan et al.   TETRAHEDRON LETTERS

Synthetic chalcones as efficient inhibitors of Mycobacterium tuberculosis protein tyrosine phosphatase PtpA

(2008) Louise Domeneghini Chiaradia et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Thallium(III)p-Tosylate Mediated Oxidative 2,3-Aryl Rearrangement: A New Useful Route to Ipriflavone and Its Analogs

(2008) M. Muthukrishnan et al.   SYNTHETIC COMMUNICATIONS