Radiosynthesis and evaluation of N-(3,4-dimethylisoxazol-5-yl)piperazine-4-[4-(4-fluorophenyl)thiazol-2-yl]-1-[11C]carboxamide for in vivo positron emission tomography imaging of fatty acid amide hydrolase in brain

The Fatty Acid Amide Hydrolase C385A Variant Affects Brain Binding of the Positron Emission Tomography Tracer [11C]CURB

(2015) Isabelle Boileau et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Development of [11C]MFTC for PET Imaging of Fatty Acid Amide Hydrolase in Rat and Monkey Brains

(2014) Katsushi Kumata et al.   ACS Chemical Neuroscience

PET Imaging of Fatty Acid Amide Hydrolase with [18F]DOPP in Nonhuman Primates

(2014) Benjamin H. Rotstein et al.   MOLECULAR PHARMACEUTICS

Carbonic Anhydrase Inhibitors: Design, Synthesis, and Biological Evaluation of Novel Sulfonyl Semicarbazide Derivatives

(2014) Jayashree Pichake et al.   ACS Medicinal Chemistry Letters

Development and characterization of a promising fluorine-18 labelled radiopharmaceutical for in vivo imaging of fatty acid amide hydrolase

(2013) Oleg Sadovski et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Design, synthesis, and biological evaluation of a series of piperazine ureas as fatty acid amide hydrolase inhibitors

(2013) Mitsunori Kono et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Inhibition of fatty acid amide hydrolase (FAAH) as a novel therapeutic strategy in the treatment of pain and inflammatory diseases in the gastrointestinal tract

(2013) Maciej Sałaga et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Synthesis and preclinical evaluation of [11C-carbonyl]PF-04457845 for neuroimaging of fatty acid amide hydrolase

(2013) Justin W. Hicks et al.   NUCLEAR MEDICINE AND BIOLOGY

Discovery of MK-3168: A PET Tracer for Imaging Brain Fatty Acid Amide Hydrolase

(2013) Ping Liu et al.   ACS Medicinal Chemistry Letters

Synthesis, SAR study, and biological evaluation of a series of piperazine ureas as fatty acid amide hydrolase (FAAH) inhibitors

(2012) Mitsunori Kono et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Fatty Acid Amide Hydrolase Inhibitors – Progress and Potential

(2012) Ish K. Khanna et al.   CNS & Neurological Disorders-Drug Targets

Mapping Human Brain Fatty Acid Amide Hydrolase Activity with PET

(2012) Pablo M Rusjan et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Radiosynthesis and Evaluation of [11C-Carbonyl]-Labeled Carbamates as Fatty Acid Amide Hydrolase Radiotracers for Positron Emission Tomography

(2012) Alan A. Wilson et al.   JOURNAL OF MEDICINAL CHEMISTRY

Inhibiting the breakdown of endogenous opioids and cannabinoids to alleviate pain

(2012) Bernard P. Roques et al.   NATURE REVIEWS DRUG DISCOVERY

[11C]Sorafenib: Radiosynthesis and preliminary PET study of brain uptake in P-gp/Bcrp knockout mice

(2011) Chiharu Asakawa et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Radiosynthesis of [2-11C-carbonyl]dantrolene using [11C]phosgene for PET

(2010) Yuuki Takada et al.   APPLIED RADIATION AND ISOTOPES

[11C]CURB: Evaluation of a novel radiotracer for imaging fatty acid amide hydrolase by positron emission tomography

(2010) Alan A. Wilson et al.   NUCLEAR MEDICINE AND BIOLOGY

Simple and effective method for producing [11C]phosgene using an environmental CCl4 gas detection tube

(2009) Masanao Ogawa et al.   NUCLEAR MEDICINE AND BIOLOGY

PET radiotracers: crossing the blood–brain barrier and surviving metabolism

(2009) Victor W. Pike   TRENDS IN PHARMACOLOGICAL SCIENCES

Discovery and Development of Fatty Acid Amide Hydrolase (FAAH) Inhibitors

(2008) Mark Seierstad et al.   JOURNAL OF MEDICINAL CHEMISTRY