Article
Immunology
Donald R. R. Walkinshaw, Meghan E. E. Wright, Marni Williams, Tanya M. F. Scarapicchia, Jean-Louis Excler, Ryan E. E. Wiley, Anne E. E. Mullin
Summary: This study presents a novel Strep A vaccine global demand and financial forecast model, estimating the potential global demand, revenue and profits for a hypothetical Strep A vaccine, as well as conducting a net present value analysis of the required capital investments for its development. Positive net present values were calculated for various developer scenarios and target populations, indicating a viable commercial market for a Strep A vaccine. It is hoped that this study will inform industry decision-making and drive increased prioritization and investment in Strep A vaccine research and development.
Review
Immunology
Xinyu Wang, Qian-Nan Jia, Mengyin Wu, Mingjuan Liu, Jun Li
Summary: This study conducted a bibliometric analysis to assess the global research trends and impact of publications related to melanoma and vaccine therapy. The results showed that melanoma and vaccine therapy have gained significant attention in the field of cancer immunotherapy, with increasing research output and citation impact. The United States, China, and their organizations are leading in terms of publication output, and collaborative research networks are prominent. Clinical trials evaluating the safety and efficacy of vaccination treatment in melanoma patients are the focus of research.
Article
Immunology
Venerando Rapisarda, Francesca Vella, Caterina Ledda, Massimiliano Barattucci, Tiziana Ramaci
Summary: Vaccines are crucial in controlling diseases, particularly in the context of the COVID-19 pandemic. Study findings indicate that factors such as vaccine confidence, positive emotions, and internal locus of control play a significant role in vaccine recommendation by healthcare professionals. Improving institutional communication targeted at doctors is essential to enhance their role as vaccination facilitators.
Review
Immunology
Cassandra Vujovich-Dunn, Jessica Kaufman, Catherine King, S. Rachel Skinner, Handan Wand, Rebecca Guy, Julie Leask
Summary: This systematic review and meta-analysis found that decision aids may have a slight impact on vaccine uptake and decisional conflict. However, variations in the content, format, and delivery method of decision aids across studies may affect their effectiveness, highlighting the need for standardization and comparison in future research.
Review
Multidisciplinary Sciences
Danya F. Vears, Joel T. Minion, Stephanie J. Roberts, James Cummings, Mavis Machirori, Mwenza Blell, Isabelle Budin-Ljosne, Lorraine Cowley, Stephanie O. M. Dyke, Clara Gaff, Robert Green, Alison Hall, Amber L. Johns, Bartha M. Knoppers, Stephanie Mulrine, Christine Patch, Eva Winkler, Madeleine J. Murtagh
Summary: The systematic review of empirical literature on stakeholders' perspectives of returning individual research results (IRR) from genomic research reveals a high interest from both participants and the general public, with researchers and health professionals showing a willingness to provide such results while maintaining a cautious stance. Priority is given to results that have the potential to change clinical management, with professional stakeholders more inclined to return reliable and clinically relevant results. The lack of evidence for enduring psychological harm and clear benefits to some research participants suggest researchers should prioritize returning actionable IRRs.
Review
Surgery
Ying Yang Ting, Jesse D. Ey, Ellie C. Treloar, Jessica L. Reid, Emma L. Bradshaw, Guy J. Maddern
Summary: This study evaluated the effectiveness of patient question prompting documents in surgical outpatient consultations. The results suggest that question prompt lists can improve patient engagement and patient-doctor communication.
Review
Medicine, General & Internal
Oluwatosin Olaseni Odubela, Nkiruka Odunukwe, Nasheeta Peer, Adesola Z. Musa, Babatunde L. Salako, A. P. Kengne
Summary: This study aims to systematically review published prediction models developed and/or validated for prevalent and incident CKD in people living with HIV, analyze their characteristics, compare performance, and assess methodological quality and applicability.
Review
Medicine, General & Internal
Karin Tobin, Omeid Heidari, Connor Volpi, Shereen Sodder, Dustin Duncan
Summary: This scoping review identified geofencing as an emerging technology that is acceptable and feasible for intervention in various populations and health outcomes. Future studies should provide rationale for geofencing locations and user input, as well as focus on the mechanisms of action to better understand the effectiveness of geofencing interventions.
Review
Orthopedics
Michael Kim, Aryan Haratian, Amir Fathi, Daniel R. Kim, Nilay Patel, Ioanna K. Bolia, Laith K. Hasan, Frank A. Petrigliano, Alexander E. Weber
Summary: This study reviewed the cases of athletes who failed to return to sports after arthroscopic Bankart repair. It found that the rate of failure to return to sports was estimated to be 15.6%, with most athletes citing shoulder-related reasons as the primary factor preventing their return.
AMERICAN JOURNAL OF SPORTS MEDICINE
(2023)
Review
Biochemistry & Molecular Biology
Agnieszka Markiewicz, Dawid Sigorski, Mateusz Markiewicz, Agnieszka Owczarczyk-Saczonek, Waldemar Placek
Summary: Caspase-14, a unique member of the caspase family, regulates cornification rather than apoptosis, playing a crucial role in skin barrier formation. Extensive research has expanded our understanding of its role in cell homeostasis and clinical implications, particularly in the pathophysiology of various diseases.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Review
Virology
Frank Eric Tatsing Foka, Hazel Tumelo Mufhandu
Summary: Antiretroviral therapies have revolutionized the management of HIV infection, but virologic failure remains a challenge in the long-term management of HIV-infected individuals. Efforts to address virologic failure include improving treatment adherence, regular monitoring, and the development of novel antiretroviral agents.
Review
Engineering, Civil
Foad Kiakojouri, Valerio De Biagi, Bernardino Chiaia, Mohammad Reza Sheidaii
Summary: This paper discusses the impact of abnormal events on the progressive collapse of structures and provides strengthening and retrofitting techniques to mitigate progressive collapse. The focus is on the influence of parameters such as the topology of the structure, nature of the triggering event, size of the initial failure, typology of the collapse, and seismic design requirements on the strengthening strategy.
ENGINEERING STRUCTURES
(2022)
Review
Chemistry, Multidisciplinary
Tracy El Achkar, Helene Greige-Gerges, Sophie Fourmentin
Summary: Deep eutectic solvents, emerging in green chemistry only seventeen years ago, have led to a plethora of publications covering various research areas and diverse fields of application. They are seen as promising alternatives to conventional organic solvents due to their straightforward preparation using highly accessible and natural compounds, as well as high tunability in properties. The physicochemical properties of these solvents, such as phase behavior, density, viscosity, ionic conductivity, surface tension, and polarity, can be controlled by factors like the choice of forming compounds, molar ratio, temperature, and water content.
ENVIRONMENTAL CHEMISTRY LETTERS
(2021)
Review
Orthopedics
Hytham S. Salem, Do H. Park, Stephen G. Thon, Jonathan T. Bravman, Adam J. Seidl, Eric C. McCarty, Rachel M. Frank
Summary: Most patients can expect to return to playing golf approximately 6 months after shoulder arthroplasty, with lower rates of return observed after RSA and HA compared to TSA. The data presented in the review can assist physicians in counseling patients who wish to continue golf participation after shoulder arthroplasty.
AMERICAN JOURNAL OF SPORTS MEDICINE
(2021)
Review
Computer Science, Hardware & Architecture
Sree Krishna Das, Fatma Benkhelifa, Yao Sun, Hanaa Abumarshoud, Qammer H. Abbasi, Muhammad Ali Imran, Lina Mohjazi
Summary: Sixth generation (6G) internet of things (IoT) networks are being developed to create smart and automated systems that meet user demands. Reconfigurable intelligent surfaces (RISs) are introduced as a potential technology to improve system performance in various aspects. This study provides an overview of the advancement of RISs and machine learning (ML) algorithms, discusses the integration of different ML techniques in RISs, and surveys the application of existing ML solutions in dynamic IoT networks. The challenges and future directions in integrating RISs and other methods in upcoming IoT networks are also presented.
