期刊
SCHIZOPHRENIA RESEARCH
卷 101, 期 1-3, 页码 161-168出版社
ELSEVIER SCIENCE BV
DOI: 10.1016/j.schres.2007.12.477
关键词
psychosis; high-risk; adolescents; cognition; sex differences; bio-risk markers
类别
资金
- NIMH NIH HHS [R01 MH062066-05, U01 MH081988, R01 MH062066, R01 MH4062066] Funding Source: Medline
- NATIONAL INSTITUTE OF MENTAL HEALTH [R01MH062066] Funding Source: NIH RePORTER
This study examined neurocognitive predictors of conversion to Axis I psychosis among adolescents at high-risk for psychosis (AHRP). There were no significant differences in neurocognitive performance between adolescents at high-risk for psychosis who converted (AHRP+) and adolescents at high-risk for psychosis who did not convert (AHRP-). Within-sex comparisons revealed a relation between risk status and performance among females, with AHRP+ performing below AHRP-, but this effect did not hold for males. Between-sex comparisons revealed AHRP- males performed worse than AHRP- females on several measures. Across groups, males performed better than their female counterparts on select measures. Results are discussed in terms of implications for use of neurocognitive profiles as bio-risk markers of psychosis, while considering sex differences. (C) 2008 Elsevier B.V. All rights reserved.
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