期刊
RSC ADVANCES
卷 5, 期 74, 页码 60101-60105出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/c5ra11168d
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资金
- MINECO (Gobierno de Espana)
- FEDER (EU) [CTQ2013-47494-P]
- Generalitat Valenciana [ISIC2012/001]
- Universitat de Valencia
An organocatalytic enantioselective aza-Friedel-Crafts addition of 2-naphthols to benzoxathiazine 2,2-dioxides is described using a quinine-derived bifunctional catalyst. The method allows the use of a wide range of aromatic compounds as nucleophiles, including 1-naphthol and sesamol, and benzoxathiazines 2,2-dioxides, expanding the existing state of the art enantioselective synthesis of aminomethylnaphthol derivatives.
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