DISC1 in Schizophrenia: Genetic Mouse Models and Human Genomic Imaging

The DISC1 Ser704Cys substitution affects centrosomal localization of its binding partner PCM1 in glia in human brain

(2010) S. L. Eastwood et al.   HUMAN MOLECULAR GENETICS

Disrupted-in-Schizophrenia-1 expression is regulated by  -site amyloid precursor protein cleaving enzyme-1-neuregulin cascade

(2010) S. Seshadri et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Dysregulation of the Norepinephrine Transporter Sustains Cortical Hypodopaminergia and Schizophrenia-Like Behaviors in Neuronal Rictor Null Mice

(2010) Michael A. Siuta et al.   PLOS BIOLOGY

Roles of the Akt/GSK-3 and Wnt Signaling Pathways in Schizophrenia and Antipsychotic Drug Action

(2009) Zachary Freyberg et al.   AMERICAN JOURNAL OF PSYCHIATRY

Animal models of gene–environment interactions in schizophrenia

(2009) Yavuz Ayhan et al.   BEHAVIOURAL BRAIN RESEARCH

Oligomer Assembly of the C-Terminal DISC1 Domain (640−854) Is Controlled by Self-Association Motifs and Disease-Associated Polymorphism S704C

(2009) S. Rutger Leliveld et al.   BIOCHEMISTRY

Disrupted in Schizophrenia 1 Regulates Neuronal Progenitor Proliferation via Modulation of GSK3β/β-Catenin Signaling

(2009) Yingwei Mao et al.   CELL

DTNBP1 is associated with imaging phenotypes in schizophrenia

(2009) Katherine L. Narr et al.   HUMAN BRAIN MAPPING

The relationship of anterior thalamic radiation integrity to psychosis risk associated neuregulin-1 variants

(2009) E Sprooten et al.   MOLECULAR PSYCHIATRY

Chromosome 8p as a potential hub for developmental neuropsychiatric disorders: implications for schizophrenia, autism and cancer

(2009) R Tabarés-Seisdedos et al.   MOLECULAR PSYCHIATRY

DISC-1 Leu607Phe alleles differentially affect centrosomal PCM1 localization and neurotransmitter release

(2009) S L Eastwood et al.   MOLECULAR PSYCHIATRY

Roles of Disrupted-In-Schizophrenia 1-Interacting Protein Girdin in Postnatal Development of the Dentate Gyrus

(2009) Atsushi Enomoto et al.   NEURON

The Disrupted-in-Schizophrenia-1 Ser704Cys polymorphism and brain morphology in schizophrenia

(2009) Tsutomu Takahashi et al.   PSYCHIATRY RESEARCH-NEUROIMAGING

Rare structural variants in schizophrenia: one disorder, multiple mutations; one mutation, multiple disorders

(2009) Jonathan Sebat et al.   TRENDS IN GENETICS

Recruitment of PCM1 to the Centrosome by the Cooperative Action of DISC1 and BBS4

(2008) Atsushi Kamiya et al.   ARCHIVES OF GENERAL PSYCHIATRY

Elucidating the relationship between DISC1, NDEL1 and NDE1 and the risk for schizophrenia: Evidence of epistasis and competitive binding

(2008) K. E. Burdick et al.   HUMAN MOLECULAR GENETICS

DTNBP1, a schizophrenia susceptibility gene, affects kinetics of transmitter release

(2008) Xiao-Wei Chen et al.   JOURNAL OF CELL BIOLOGY

Schizophrenia-Related Neural and Behavioral Phenotypes in Transgenic Mice Expressing Truncated Disc1

(2008) S. Shen et al.   JOURNAL OF NEUROSCIENCE

Enlargement of the lateral ventricles in mutant DISC1 transgenic mice

(2008) M V Pletnikov et al.   MOLECULAR PSYCHIATRY

Effect of disrupted-in-schizophrenia-1 on pre-frontal cortical function

(2008) D P Prata et al.   MOLECULAR PSYCHIATRY

A threonine to isoleucine missense mutation in the pericentriolar material 1 gene is strongly associated with schizophrenia

(2008) S R Datta et al.   MOLECULAR PSYCHIATRY

Rare chromosomal deletions and duplications increase risk of schizophrenia

(2008) Jennifer L. Stone et al.   NATURE

Large recurrent microdeletions associated with schizophrenia

(2008) Hreinn Stefansson et al.   NATURE

Dysbindin deficiency in sandy mice causes reduction of snapin and displays behaviors related to schizophrenia

(2008) Y FENG et al.   SCHIZOPHRENIA RESEARCH

Rare Structural Variants Disrupt Multiple Genes in Neurodevelopmental Pathways in Schizophrenia

(2008) T. Walsh et al.   SCIENCE