Article
Rheumatology
Masanori Nakayama, Takefumi Furuya, Eisuke Inoue, Eiichi Tanaka, Katsunori Ikari, Hisashi Yamanaka, Masayoshi Harigai
Summary: This study investigated the prevalence and factors associated with sarcopenia in Japanese patients with rheumatoid arthritis (RA). The results showed significant associations between age, body mass index (BMI), disease duration, history of fracture, pain severity, and medication use with sarcopenia. In addition, among older patients with RA, female sex was also associated with sarcopenia.
CLINICAL RHEUMATOLOGY
(2023)
Article
Geriatrics & Gerontology
Siyu Chen, Shiqi Chen, Zhijian Zhao, Xueqing Cao, Zhangling Chen, Jun Lin
Summary: Lower serum 25(OH)D concentration is associated with higher all-cause mortality in patients with rheumatoid arthritis, while the association between omega-3 % and mortality is not significant. Optimizing serum vitamin D levels may be an important factor in reducing mortality risk in this population.
Article
Endocrinology & Metabolism
Masanori Nakayama, Takefumi Furuya, Eisuke Inoue, Eiichi Tanaka, Katsunori Ikari, Hisashi Yamanaka, Masayoshi Harigai
Summary: This study found that vitamin D deficiency is a significant risk factor for new fractures in Japanese female patients over the age of 50 with rheumatoid arthritis, suggesting that screening for serum 25(OH)D levels could potentially reduce the risk of fractures.
ARCHIVES OF OSTEOPOROSIS
(2021)
Article
Rheumatology
Naohiro Sugitani, Eiichi Tanaka, Eisuke Inoue, Mai Abe, Eri Sugano, Kumiko Saka, Moeko Ochiai, Yoko Higuchi, Rei Yamaguchi, Naoki Sugimoto, Katsunori Ikari, Ayako Nakajima, Hisashi Yamanaka, Masayoshi Harigai
Summary: This article aims to investigate the mortality rate of patients with early rheumatoid arthritis (RA) over the past 17 years. The study found that the 5-year survival rate of early RA patients in Japan has been comparable to the general population and remained stable.
MODERN RHEUMATOLOGY
(2023)
Article
Medicine, General & Internal
Drazen Bedekovic, Damir Kirner, Ivica Bosnjak, Aleksandar Kibel, Sandra Saric, Srdan Novak, Visnja Prus
Summary: Rheumatoid arthritis (RA) increases the risk of cardiovascular diseases (CVDs), mainly due to arterial hypertension (HT). However, this study found no difference in HT prevalence between RA and osteoarthritis (OA) groups, but the RA group had a higher incidence of CVDs. RA patients with long-term remission had a slightly lower HT prevalence.
JOURNAL OF CLINICAL MEDICINE
(2023)
Review
Medicine, General & Internal
Mengduan Pang, Zhe Sun, Hongfeng Zhang
Summary: This meta-analysis compared the risk of all-cause mortality between biological/targeted synthetic disease-modifying antirheumatic drugs (b/tsDMARDs) and non-b/tsDMARDs in patients with rheumatoid arthritis (RA). The results showed that compared to non-b/tsDMARDs, antitumor necrosis factor therapy was associated with an increased risk of mortality.
Article
Public, Environmental & Occupational Health
Juyeong Kim, Eun-Cheol Park
Summary: This study aimed to assess the specific associations between stroke and all-cause and cause-specific mortality among Korean adults. The results showed that stroke was associated with a higher risk of all-cause, natural cause, and suicide mortality.
JOURNAL OF PUBLIC HEALTH
(2023)
Article
Food Science & Technology
Hyein Jung, Sangah Shin
Summary: This study finds that higher intake of tomatoes and lycopene is inversely associated with the risk of cardiovascular disease (CVD) mortality, and lycopene consumption is associated with a lower risk of all-cause mortality.
MOLECULAR NUTRITION & FOOD RESEARCH
(2023)
Article
Rheumatology
Eunyoung Emily Lee, Anna Shin, Joongyub Lee, Joo Ho Lee, You-Jung Ha, Yun Jong Lee, Eun Bong Lee, Yeong Wook Song, Eun Ha Kang
Summary: The study compared the mortality rates between RA patients and the general population in Korea, revealing a 1.5-fold increase in all-cause mortality among RA patients. Apart from cancer, respiratory disease, cardiovascular disease, systemic rheumatic diseases, and infection were also significant causes of death in RA patients.
Article
Immunology
Erye Zhou, Jian Wu, Xin Zhou, Yufeng Yin
Summary: This study investigated the association between neutrophil-to-lymphocyte ratio (NLR) and all-cause and cardiovascular mortality risk in individuals with rheumatoid arthritis (RA). The study found that individuals with higher NLR had a 2-fold increased risk of long-term mortality. NLR may serve as an inexpensive and widely available prognostic marker in RA.
FRONTIERS IN IMMUNOLOGY
(2023)
Article
Rheumatology
Jeffrey A. Sparks, Yinzhu Jin, Soo-Kyung Cho, Seanna Vine, Rishi Desai, Tracy J. Doyle, Seoyoung C. Kim
Summary: This study investigated the prevalence, incidence, and cause-specific mortality of RA-associated interstitial lung disease (RA-ILD) among older US patients with RA. The results showed that RA-ILD was present or developed in nearly 5% of patients, and RA-ILD was associated with excess total, respiratory, and cancer mortality compared with RA without ILD.
Article
Rheumatology
Naoki Sugimoto, Eiichi Tanaka, Eisuke Inoue, Mai Abe, Eri Sugano, Naohiro Sugitani, Kumiko Saka, Moeko Ochiai, Yoko Higuchi, Rei Yamaguchi, Katsunori Ikari, Ayako Nakajima, Hisashi Yamanaka, Masayoshi Harigai
Summary: The study investigated the trends in risks of malignancies in patients with rheumatoid arthritis (RA) in Japan. The results showed that there was no increase in malignancy risk in Japanese patients with RA, despite the expanding use of methotrexate and biologics. The overall risk for malignancies was similar to the general Japanese population, while the risk for malignant lymphoma was significantly increased.
MODERN RHEUMATOLOGY
(2023)
Article
Public, Environmental & Occupational Health
Mahdi Nalini, Masoud Khoshnia, Farin Kamangar, Maryam Sharafkhah, Hossein Poustchi, Akram Pourshams, Gholamreza Roshandel, Samad Gharavi, Mahdi Zahedi, Alireza Norouzi, Masoud Sotoudeh, Arash Nikmanesh, Paul Brennan, Paolo Boffetta, Sanford M. Dawsey, Christian C. Abnet, Reza Malekzadeh, Arash Etemadi
Summary: This study investigated the joint effect of diabetes and opiate use on mortality, finding that individuals with both diabetes and opiate use had a significantly higher risk of all-cause mortality. The results highlight the importance of public awareness on the health effects of opiates and the need to improve diabetes care for individuals at risk of opiate use.
INTERNATIONAL JOURNAL OF EPIDEMIOLOGY
(2021)
Article
Engineering, Environmental
Yun Fan, Chengzhe Tao, Zhi Li, Yuna Huang, Wenkai Yan, Shuangshuang Zhao, Beibei Gao, Qiaoqiao Xu, Yufeng Qin, Xinru Wang, Zhihang Peng, Adrian Covaci, You Li, Yankai Xia, Chuncheng Lu
Summary: Wide exposure to endocrine-disrupting chemicals (EDCs) poses a great risk on human health. This study aimed to comprehensively estimate the association between EDCs exposure and mortality risk. By investigating a large cohort, the study found that certain EDCs were positively associated with all-cause mortality, cancer mortality, and cardiovascular disease mortality. Additionally, it was determined that EDCs exposure may cause a significant number of total deaths and high economic costs.
ENVIRONMENTAL SCIENCE & TECHNOLOGY
(2023)
Article
Surgery
Cesar Beugniez, Alain Sauvanet, Laurent Sulpice, Sebastien Gaujoux, Olivier Turrini, Stephanie Truant, Lilian Schwarz, Guillaume Piessen, Jean Marc Regimbeau, Fabrice Muscari, Mustapha Adham, Francois Pattou, Lucil Schneider, Guillaume Clement, Jean-Robert Delpero, Francois-Rene Pruvot, Mehdi El Amrani
Summary: The analysis of deceased patients after pancreatectomy in high-volume centers in France revealed that 30% of deaths were preventable, mainly due to inadequate preoperative assessment and postoperative management. Factors such as young age and arterial resection were associated with avoidable mortality.