Review
Medicine, General & Internal
Lourdes Vicent, Raquel Luna, Manuel Martinez-Selles
Summary: Infective endocarditis in children is a rare and complex disease. The most common risk factor is congenital heart disease, but other factors such as central venous catheter carriers or children with chronic debilitating conditions have gained relevance. Diagnosis has improved with the use of multimodal imaging techniques, and early antibiotic treatment is crucial. Complications are frequent and cause significant morbidity.
JOURNAL OF CLINICAL MEDICINE
(2022)
Review
Medicine, General & Internal
Antonio Bustos-Merlo, Antonio Rosales-Castillo, Fernando Cobo, Carmen Hidalgo-Tenorio
Summary: Mycoplasma hominis is a common microorganism in the lower genital tract, but can rarely cause blood culture-negative infective endocarditis. A new case of endocarditis caused by M. hominis on a pacemaker lead was reported in this study, and a narrative review was conducted. Among previously published cases, the majority were male with a history of valve surgery. The diagnosis was made through culture or molecular techniques, and the prognosis was favorable in most cases. The most commonly prescribed antibiotics were doxycycline, quinolones, and clindamycin.
JOURNAL OF CLINICAL MEDICINE
(2022)
Review
Infectious Diseases
Alice Mule, Francesco Rossini, Alessio Sollima, Angelica Lenzi, Benedetta Fumarola, Silvia Amadasi, Erika Chiari, Silvia Lorenzotti, Barbara Saccani, Evelyn Van Hauwermeiren, Paola Lanza, Alberto Matteelli, Francesco Castelli, Liana Signorini
Summary: This article presents a case of an immunocompetent 74-year-old man affected by Trichosporon ashaii endocarditis of the prosthetic aortic valve. The patient was successfully treated and remained recurrence-free after 5 years of follow-up, highlighting the importance of timely treatment and individualized prophylactic therapy.
Review
Immunology
Nadji Hannachi, Florent Arregle, Hubert Lepidi, Jean-Pierre Baudoin, Frederique Gouriet, Helene Martel, Sandrine Hubert, Benoit Desnues, Alberto Riberi, Jean-Paul Casalta, Gilbert Habib, Laurence Camoin-Jau
Summary: Whipple's disease is a chronic multisystemic infection caused by Tropheryma whipplei. It is often misunderstood due to its intracellular localization and absence of pathognomonic signs, leading to misdiagnosis. This case report highlights a patient initially treated for presumed rheumatoid arthritis who was later diagnosed with Whipple's disease after presenting with infectious endocarditis. The atypical presentation observed might be attributed to the anti-inflammatory treatment given for the initial misdiagnosis.
FRONTIERS IN IMMUNOLOGY
(2022)
Review
Public, Environmental & Occupational Health
Ye Qiu, Yongying Shi, Ying Mai, Zhile Wu, Jing Guan, Juanni Huang, Danhong Su, Feng Ye, Zhengtu Li
Summary: This report describes a case of subacute infective endocarditis caused by the rare pathogen Lodderomyces elongisporus in a 58-year-old woman. The infection was confirmed through blood fungal culture and whole-genome sequencing. The patient was treated with antifungals, mitral replacement, and endocardial vegetation removal surgery.
FRONTIERS IN PUBLIC HEALTH
(2023)
Review
Oncology
Yiting Li, Zile Chen, Shu Nie, Zhouwei Wu
Summary: Dermatofibrosarcoma protuberans is a rare skin cancer with high recurrence and low metastasis. Atrophic dermatofibrosarcoma protuberans is a rare variant often misdiagnosed as benign lesions. Early identification and understanding of these variants can improve prognosis.
FRONTIERS IN ONCOLOGY
(2023)
Review
Pediatrics
Yanqiang Du, Zhan Zhang, Chao Chen, Han Xia, Hua Zhang, Zhangyan Guo, Yi Wang
Summary: This study reports the clinical features of the first child with infective endocarditis caused by Abiotrophia defectiva in mainland China and the detection of A. defectiva by metagenomic next-generation sequencing in patients with endocarditis, providing valuable insights into the disease.
FRONTIERS IN PEDIATRICS
(2022)
Review
Immunology
Robin Jacquot, Maurine Jouret, Mathieu Gerfaud Valentin, Mael Richard, Yvan Jamilloux, Florent Rousset, Jean-Francois Emile, Julien Haroche, Lars Steinmuller, Franck Zekre, Alice Phan, Alexandre Belot, Pascal Seve
Summary: H syndrome is a rare autosomal recessive genetic disorder characterized by various clinical features, including cutaneous hyperpigmentation, hypertrichosis, hepatosplenomegaly, heart anomalies, hearing loss, hypogonadism, short stature, hallux valgus, hyperglycemia, and fixed joint contractures. This disorder is caused by mutations in the SLC29A3 gene, resulting in abnormal function and proliferation of histiocytes. We reported two cases of H syndrome, one diagnosed in adulthood and the other in childhood, that showed significant improvement after treatment with Tocilizumab.
FRONTIERS IN IMMUNOLOGY
(2023)
Review
Infectious Diseases
Lorenzo Bertolino, Mohammad Said Ramadan, Rosa Zampino, Emanuele Durante-Mangoni
Summary: This systematic review summarises the clinical characteristics, management, and outcomes of patients with MitraClip-related infective endocarditis. The results suggest that MitraClip-related infective endocarditis mostly affects elderly, comorbid patients, is mainly caused by Staphylococcus aureus, and has a poor prognosis regardless of the therapeutic approach.
Review
Cardiac & Cardiovascular Systems
Yingmiao Zhang, Jing Wang, Yu Zhan, Ruizhi Tang, Hui Wang, Tian Qin, Zhongxin Lu
Summary: Streptococcus sinensis, initially identified as a causative agent for infective endocarditis in Hong Kong, has emerged as a worldwide pathogen. In this paper, we isolated a closely related strain from a young patient in mainland China and provided a comprehensive comparison of its clinical characteristics with reported cases.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2022)
Review
Pediatrics
Yu Xiang, Fei Li, Zhenfeng Song, Zhi Yi, Chengqing Yang, Jiao Xue, Ying Zhang
Summary: This article reports two cases of atypical hemiplegic migraine presenting as acute encephalopathy, and summarizes a total of 160 clinical cases through literature review, providing references for early diagnosis and treatment of this condition.
FRONTIERS IN PEDIATRICS
(2023)
Review
Physiology
Fang Ren, Gang Liu, Tifang Wang, Meijun Li, Zhiqiang Guo
Summary: Ovarian pregnancy is an extremely rare condition, typically presenting as a ruptured case. The definitive diagnosis of ruptured ovarian pregnancy is challenging. This report presents two cases of unruptured ovarian pregnancies detected during laparoscopy and reviews the existing literature to enhance our understanding of the clinical characteristics of this rare ectopic pregnancy site.
FRONTIERS IN PHYSIOLOGY
(2022)
Review
Clinical Neurology
Chenyue Hang, Yan Yan
Summary: This study described two Chinese female patients with MEWDS who initially presented with visual snow, which is a rare symptom in MEWDS. The findings suggest that visual snow may precede the onset of MEWDS.
FRONTIERS IN NEUROLOGY
(2022)
Review
Clinical Neurology
Lei Chen, Ping Zhang, Xuan Zhu, Minmin Zhang, Benqiang Deng
Summary: Accurate definition of stroke etiology is crucial for effective treatment. Both APS and IE can independently increase the risk of ischemic stroke in young adults. When an embolic stroke occurs with both IE and APS, it is difficult to identify the source of embolism. In this case report, a 19-year-old male patient was diagnosed with APS and IE accompanying stroke, and the embolic source was identified as aortic valve vegetation. Early diagnosis and surgical intervention resulted in a favorable clinical outcome without stroke recurrence during the 1-year follow-up.
FRONTIERS IN NEUROLOGY
(2022)
Review
Medicine, Research & Experimental
Shuangfeng Huang, Junliang Zhang, Manli Tao, Yaodong Lv, Luyao Xu, Zhigang Liang
Summary: Chorea-acanthocytosis (ChAc) is a rare neurodegenerative disease with various early clinical manifestations, thought to be caused by VPS13A mutations. The final diagnosis of ChAc can be established by genetic analysis or protein expression via Western blotting. Supportive treatments and nursing play a crucial role in improving the quality of life for patients, while the impact of neuroimaging and neuropathological diagnosis in a larger group of ChAc should be further investigated in future studies.
EUROPEAN JOURNAL OF MEDICAL RESEARCH
(2022)