期刊
RUSSIAN JOURNAL OF BIOORGANIC CHEMISTRY
卷 37, 期 2, 页码 207-216出版社
MAIK NAUKA/INTERPERIODICA/SPRINGER
DOI: 10.1134/S1068162010061019
关键词
peptides; amino acid sequence; HIV-1 integrase and revertase inhibition; marine invertebrates; marine polychaetes
资金
- MNTC [3197r]
A homogeneous peptide with a mass of 683 Da which inhibits HIV-1 integrase with IC(50) 3 x 10(-5) M was separated from aqueous extracts of a marine worm Eunicidae sp. by multistage chromatography purification. The Asp-Leu-Hse-His-Ala-Gln structure was proposed for this peptide according to amino acid analysis, automated amino acid Edman sequences, and TLC with witness homoserine and MS/MS fragmentation. The proposed structure is the first example of a natural peptide containing an amino acid homoserine residue.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据