Article
Chemistry, Inorganic & Nuclear
Taylor V. Fetrow, Brenna K. Cashman, Stephanie H. Carpenter, Michael T. Janicke, Nickolas H. Anderson, Bonnie E. Klamm, Harris E. Mason, Aaron M. Tondreau
Summary: Gallium trichloride was used as a solvent for the oxidative dissolution of lanthanide metals cerium and holmium, leading to the formation of inorganic complexes. The best results were achieved with specific stoichiometric ratios, and recrystallization produced new complexes with reversible coordination observed. The complexes were characterized using various analytical techniques including elemental analysis, spectroscopy, and NMR.
INORGANIC CHEMISTRY
(2023)
Article
Chemistry, Organic
Wei Wang, Shu-Yun Jiang, Jun-Rong Song, Wei Wu, Jun Shi, Zhi-Yao Li, Ying-Ai Wu, Qin Chi, Wei-Dong Pan, Hai Ren
Summary: The first example of cyclization cross-coupling of tryptophols and tryptamines has been achieved by copper catalysis, resulting in the direct construction of a new class of heterocyclic 3a,3a'-bisindolines. Mechanistic control experiments revealed that the copper catalyst selectively coordinates with the nitrogen moiety of the tryptamine, initiating the oxidation, and a nucleophilic-alkylation process is proposed for the carbon-carbon bond formation.
Article
Chemistry, Organic
Denis D. Borisov, Grigorii R. Chermashentsev, Roman A. Novikov, Yury V. Tomilov
Summary: The method developed allows for the synthesis of substituted beta-styrylmalonates by converting ACDCs into intermediates and then isomerizing the double bond, thereby expanding the reactions to include ACDCs with acceptor substituents at the aromatic ring.
SYNTHESIS-STUTTGART
(2021)
Article
Biochemistry & Molecular Biology
Zhuochao Teng, Yanan Han, Shuming He, Mohammad Hassan Hadizadeh, Qi Zhang, Xurong Bai, Xiaotong Wang, Yanhui Sun, Fei Xu
Summary: This study investigates the mechanisms of PCN formation from the cross-condensation of PhR with 2-CPR/3-CPR through detailed thermodynamic and kinetic calculations. The results show that naphthalene and 1-MCN are the main products from the cross-condensation of PhR with 2-CPR, while naphthalene and 2-MCN are the main products from the cross-condensation of PhR with 3-CPR.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Biochemistry & Molecular Biology
Juno Son, Zhiyuan Wu, Jinghuai Dou, Hikaru Fujita, Phuong-Lien Doan Cao, Qihui Liu, Jonathan S. Lindsey
Summary: In this study, seven target compounds and 22 intermediates were synthesized, and their corresponding indigo dyes were obtained through treatment with β-glucuronidase under physiological conditions. The results indicate that these tethered indoxyl-glucuronides can be used for bioconjugation chemistry with a visible chromogenic readout under physiological conditions.
Article
Chemistry, Organic
Bryan C. Figula, D. Lucas Kane, Kaluvu Balaraman, Christian Wolf
Summary: Cross-coupling of alkyl fluorides and organocuprates is achieved via aluminum halide mediated C-F bond activation, leading to the formation of Csp2-Csp3 and Csp3-Csp3 bonds. The reaction exhibits mild conditions and effectively controls competing side reactions, resulting in high yields and good functional group tolerance.
Article
Nanoscience & Nanotechnology
Jiajun Qin, Ming Li, Ming Yuan, Xinglei Shi, Jiliang Song, Yiyan He, Hongli Mao, Deling Kong, Zhongwei Gu
Summary: The metal gallium shows great potential in fighting infections by disrupting bacterial iron metabolism. This study reports a novel dual-cross-linked alginate hydrogel containing gallium ions, which exhibits broad-spectrum antimicrobial activity and enhanced mechanical performance. It can effectively treat infected wounds and accelerate healing.
ACS APPLIED MATERIALS & INTERFACES
(2022)
Article
Nanoscience & Nanotechnology
Jiajun Qin, Ming Li, Ming Yuan, Xinglei Shi, Jiliang Song, Yiyan He, Hongli Mao, Deling Kong, Zhongwei Gu
Summary: Gallium metal has great potential in fighting infections by disrupting bacterial iron metabolism. This study explores the use of gallium-mediated hydrogel for treating infected wounds. The innovative design of a dual-cross-linked alginate hydrogel, with gallium as a crosslinking and therapeutic agent, showed broad-spectrum antimicrobial activity and improved mechanical performance. In vitro and in vivo results demonstrated the biocompatibility, reduced bacterial growth, and accelerated healing of infected wounds, making the gallium-incorporated hydrogel an ideal antimicrobial dressing.
ACS APPLIED MATERIALS & INTERFACES
(2022)
Article
Chemistry, Analytical
Max Ruwolt, Lennart Schnirch, Diogo Borges Lima, Michal Nadler-Holly, Rosa Viner, Fan Liu
Summary: Cross-linking mass spectrometry (XL-MS) is a powerful method for investigating protein-protein interactions (PPI) in complex samples. In this study, a benchmarking dataset was generated to evaluate the effects of different mass spectrometry parameters on cross-link identification and quantification. The findings suggest that a stepped HCD-MS2 method with stepped collision energies 36-42-48 provides a large number of quantifiable cross-links with high accuracy.
ANALYTICAL CHEMISTRY
(2022)
Article
Chemistry, Physical
Xiao-Qing Han, Lei Wang, Ping Yang, Jing-Yuan Liu, Wei-Yan Xu, Chao Zheng, Ren-Xiao Liang, Shu-Li You, Junliang Zhang, Yi-Xia Jia
Summary: A palladium-catalyzed intramolecular enantioselective Mizoroki-Heck reaction of naphthalenes has been developed, leading to the formation of a series of unique heterocyclic compounds with enantiomeric excess values retained. The reaction relies on the use of a chiral sulfonamide phosphine ligand to inhibit competitive and undesired reactions.
Article
Chemistry, Multidisciplinary
Marcel Haerterich, Benedikt Ritschel, Merle Arrowsmith, Julian Boehnke, Ivo Krummenacher, Ashwini K. Phukan, Holger Braunschweig
Summary: This study reports the first examples of thermally induced, transition-metal-free cross-metathesis between an organic alkyne and inorganic B=B double bonds, resulting in the formation of novel compounds with unique properties. These compounds form via a biradical mechanism and possess distinctive reducibility.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
(2021)
Article
Chemistry, Organic
Irina A. Borisova, Daria-Maria Ratova, Konstantin Potapov, Anna Tarasova, Roman A. Novikov, Yury Tomilov
Summary: A new ionic cyclopropanation process has been developed, resulting in the formation of 1,1,2,3-tetrasubstituted cyclopropanes as the main products. These tetrasubstituted cyclopropanes can be further utilized for synthesis, including the formation of five-membered lactones through a reaction promoted by TiCl4.
JOURNAL OF ORGANIC CHEMISTRY
(2021)
Article
Chemistry, Organic
Enshen Zhang, Chen Chen, Xueling Wang, Jian Wang, Yongjia Shang
Summary: An efficient palladium-catalyzed reaction has been developed for the construction of spirooxindoles containing E-exocyclic double bonds. This reaction exhibits broad functional group tolerance and excellent chemo- and E/Z selectivities.
ORGANIC CHEMISTRY FRONTIERS
(2022)
Article
Chemistry, Multidisciplinary
Dezhao Zhu, Lulu Guo, Jianfeng Li, Chunming Cui
Summary: The synthesis of benzoborole dianions by alkali metal reduction of BN-naphthalene derivatives via a ring-contraction strategy has been developed. Different lithium salts have been obtained based on the structure of the synthesized compounds, with some of them showing good yield of oxidation products.
CHEMISTRY-A EUROPEAN JOURNAL
(2021)
Article
Chemistry, Multidisciplinary
Ayumi Kuramochi, Nobuyuki Komine, Sayori Kiyota, Masafumi Hirano
Summary: Borylated-conjugated trienes were synthesized by Ru-catalyzed cross-dimerizations for use in cross-coupling reactions, leading to the successful total synthesis of the sea slug pheromone navenone B.
BULLETIN OF THE CHEMICAL SOCIETY OF JAPAN
(2021)
Article
Chemistry, Multidisciplinary
Irina K. Goncharova, Kseniia P. Silaeva, Ashot V. Arzumanyan, Anton A. Anisimov, Sergey A. Milenin, Roman A. Novikov, Pavel N. Solyev, Yaroslav V. Tkachev, Alexander D. Volodin, Alexander A. Korlyukov, Aziz M. Muzafarov
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
(2019)
Article
Biochemistry & Molecular Biology
Mikhail S. Drenichev, Mark Bennett, Roman A. Novikov, John Mansfield, Nick Smirnoff, Murray Grant, Sergey N. Mikhailov
Article
Chemistry, Multidisciplinary
Alexey A. Festa, Olga A. Storozhenko, Nikita E. Golantsov, Karthikeyan Subramani, Roman A. Novikov, Snezhana O. Zaitseva, Mikhail S. Baranov, Alexey V. Varlamov, Leonid G. Voskressensky
Article
Chemistry, Organic
Denis D. Borisov, Grigory R. Chermashentsev, Roman A. Novikov, Yury Tomilov
TETRAHEDRON LETTERS
(2019)
Article
Chemistry, Organic
Maria A. Zotova, Roman A. Novikov, Alexander D. Volodin, Alexander A. Korlyukov, Yaroslav V. Tkachev, Victor A. Korolev, Yury V. Tomilov
EUROPEAN JOURNAL OF ORGANIC CHEMISTRY
(2019)
Article
Chemistry, Organic
Dmitry A. Denisov, Denis D. Borisov, Victor A. Korolev, Roman A. Novikov, Yury V. Tomilov
JOURNAL OF ORGANIC CHEMISTRY
(2019)
Article
Chemistry, Organic
Vera A. Alferova, Maxim V. Shuvalov, Roman A. Novikov, Alexey S. Trenin, Lubov G. Dezhenkova, Elena G. Gladkikh, Olda A. Lapchinskaya, Valeriya V. Kulyaeva, Olga P. Bychkova, Elena P. Mirchink, Pavel N. Solyev, Gulnara Kh. Kudryakova, Vladimir A. Korshun, Anton P. Tyurin
TETRAHEDRON LETTERS
(2019)
Article
Polymer Science
K. Boldyrev, E. Tatarinova, I Meshkov, N. Vasilenko, M. Buzin, R. Novikov, V. Vasil'ev, E. Shtykova, L. Feigin, A. Bystrova, S. Chvalun, A. Muzafarov
Article
Chemistry, Multidisciplinary
Dmitry A. Denisov, Denis D. Borisov, Konstantin V. Potapov, Roman A. Novikov, Yury V. Tomilov
MENDELEEV COMMUNICATIONS
(2019)
Article
Chemistry, Multidisciplinary
I. A. Borisova, A. V. Tarasova, K. V. Potapov, R. A. Novikov, Yu. V. Tomilov
RUSSIAN CHEMICAL BULLETIN
(2019)
Article
Biochemistry & Molecular Biology
Alexandra S. Latysheva, Vladimir A. Zolottsev, Alexander V. Veselovsky, Kirill A. Scherbakov, Galina E. Morozevich, Vadim S. Pokrovsky, Roman A. Novikov, Vladimir P. Timofeev, Yaroslav Tkachev, Alexander Y. Misharin
Article
Biochemistry & Molecular Biology
Anastasia A. Novoseltseva, Nikita M. Ivanov, Roman A. Novikov, Yaroslav V. Tkachev, Dmitry A. Bunin, Alexandra S. Gambaryan, Vadim N. Tashlitsky, Alexander M. Arutyunyan, Alexey M. Kopylov, Elena G. Zavyalova
Article
Chemistry, Inorganic & Nuclear
Roman A. Novikov, Anastasia A. Levina, Denis D. Borisov, Alexander D. Volodin, Alexander A. Korlyukov, Yaroslav Tkachev, Yana B. Platonova, Larisa G. Tomilova, Yury Tomilov
Article
Chemistry, Organic
Maria A. Belaya, Daniil A. Knyazev, Roman A. Novikov, Yury Tomilov
TETRAHEDRON LETTERS
(2020)
Article
Chemistry, Multidisciplinary
Ivan A. Yaremenko, Yulia Yu Belyakova, Peter S. Radulov, Roman A. Novikov, Michael G. Medvedev, Nikolai Krivoshchapov, Alexander A. Korlyukov, Igor Alabugin, Alexander O. Terent'ev
Summary: Stable bridged azaozonides can be selectively assembled through a catalyst-free three-component condensation, showing thermal stability and unique chemical properties. Their chemical stability allows for selective transformations, including novel rearrangement reactions, due to the specific properties of the amino group in aminoperoxides.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
(2021)
