Article
Engineering, Civil
Mampiandra N. H. Zafimandimby, Yongjian Liu, Biao Yan, Lei Jiang, Yinping Ma
Summary: This paper aims to determine the optimal strengthening method for hollow section T-joint under compression by comparing the increase in strength, self-weight, constructability, and aesthetic factors. Numerical research is conducted to compare the strength efficiency of each type of strengthening method. The increase in self-weight of the strengthened joint is calculated and analyzed. The results show that collar plate strengthening is the optimal type when considering all criteria combined.
Editorial Material
Automation & Control Systems
Richard G. Brereton
Summary: The concepts of Bayesian analysis are introduced through a discussion of a 2x2 confusion matrix with unequal sample sizes for each class.
JOURNAL OF CHEMOMETRICS
(2022)
Review
Biochemistry & Molecular Biology
Jongseong Ahn, Sunghoon Heo, Jihyun Lee, Duhee Bang
Summary: DNA methylation is an important epigenetic mechanism linked to mammalian cellular differentiation, gene expression regulation, and diseases. This review outlines single-cell DNA methylation profiling methods, including experimental strategies and computational data analysis, as well as highlights blind spots in basic analysis and recent alternatives. It also introduces well-known applications and discusses future developments in the field.
Article
Mechanics
Donat M. Takacs, Szabolcs Berezvai, Laszlo Kovacs
Summary: Modelling the static failure of fibre-reinforced composite laminates is a challenging problem due to the lack of physical interpretation for the parameters of mechanical models. To improve efficiency in designing mechanical experiments, a general method for quantifying the sensitivity of failure criteria parameters to failure stress states has been developed. This method helps select the most robust fit of model parameters by choosing failure stress states based on a failure model, and demonstrated its practical application on the Tsai-Wu and Puck failure models.
EUROPEAN JOURNAL OF MECHANICS A-SOLIDS
(2023)
Article
Materials Science, Textiles
Hamza El Idrissi, Abbass Seddouki
Summary: This study models the progressive damage in a notched carbon/epoxy composite laminate subjected to tensile loading using different assessment methods combined with finite element analysis. The evaluation methods proposed and assessed in this study are based on failure criteria and damage mechanics. The research aims to understand the behavior and damage phenomenon in carbon/epoxy composite laminates, considering different stacking sequences and stress concentrations. The results of the analysis are compared to experimental and numerical findings to validate the accuracy of the proposed methods.
FIBERS AND POLYMERS
(2022)
Article
Medicine, General & Internal
Lea Baecker, Rafael Garcia-Dias, Sandra Vieira, Cristina Scarpazza, Andrea Mechelli
Summary: The rise of machine learning has enabled new ways of analyzing structural neuroimaging data, such as brain age prediction, which can help in early detection of brain-based disorders. The prediction model of brain age can reflect neuroanatomical abnormalities and support differential diagnosis and treatment choices.
Review
Microbiology
Kirandeep Samby, Paul A. Willis, Jeremy N. Burrows, Benoit Laleu, Peter J. H. Webborn
Summary: Over 1 billion people worldwide are affected by neglected tropical diseases, requiring medical intervention and causing significant economic losses. Collaborative drug discovery efforts are needed to reduce the burden of these diseases in endemic regions. The release of Open Access Boxes aims to catalyze new drug discovery in neglected diseases and provide guidance for researchers to move active compounds beyond the hit identification stage.
Review
Engineering, Biomedical
Fabien Kawecki, Nicolas L'Heureux
Summary: Cardiovascular diseases, including atherosclerosis, are the leading cause of mortality worldwide. Synthetic vascular grafts are widely used for larger vessel repairs, but are inadequate for small-diameter applications. This review discusses tissue-engineering approaches, including biological textile methods, to overcome the limitations of synthetic and autologous grafts and biofabricate small-diameter vascular grafts with native-like outcomes.
Article
Radiology, Nuclear Medicine & Medical Imaging
Robert A. Price Jr, Iavor Veltchev, Teh Lin, Ahmed Eldib, Lili Chen, Lihui Jin, Xiaoming Chen, Jie Liu, Lu Wang, C. -M. Charlie Ma
Summary: A study evaluated the AAPM TG-218 recommended tolerances for IMRT QA, finding that VMAT QA failure did not strongly correlate with plan complexity under stricter criteria, and SBRT QA results showed a low correlation with target size.
PHYSICA MEDICA-EUROPEAN JOURNAL OF MEDICAL PHYSICS
(2022)
Article
Radiology, Nuclear Medicine & Medical Imaging
Robert A. Price, Iavor Veltchev, Teh Lin, Ahmed Eldib, Lili Chen, Lihui Jin, Xiaoming Chen, Jie Liu, Lu Wang, C-M Charlie Ma
Summary: The purpose of this study was to evaluate the recommended tolerances for IMRT QA for conventional and SBRT delivery. The analysis was conducted on 150 IMRT/VMAT patients with varying gamma criteria. The results showed that the tolerances and action limits varied with different criteria and had low correlation with plan complexity and target size.
PHYSICA MEDICA-EUROPEAN JOURNAL OF MEDICAL PHYSICS
(2022)
Article
Energy & Fuels
David A. Agar, Paul Hansen, Magnus Rudolfsson, Bosko Blagojevic
Summary: This study applies the behavioural TOPSIS method to evaluate and rank biomass fuel pellets produced in Sweden. The study found that pellets produced from a reference spruce/pine sawdust blend are consistently ranked ahead of other pellet types in all scenarios.
Review
Chemistry, Multidisciplinary
Barry Ezell, Christopher J. Lynch, Patrick T. Hester
Summary: The article reviews and summarizes eight multi-criteria decision analysis techniques that can help decision makers to reach unique decisions based on personally ranked criteria. These techniques allow for personalized weighting scales to reflect a more realistic state for a modeled system. The potential uses of these techniques are compared across different modeling paradigms to inform current researchers and enable new researchers to utilize methods for modeling multi-criteria decisions.
APPLIED SCIENCES-BASEL
(2021)
Article
Anesthesiology
Shan-Shan Xu, Ye Tian, Yan-Juan Ma, Yi-Min Zhou, Ying Tian, Ran Gao, Yan-Lin Yang, Linlin Zhang, Jian-Xin Zhou
Summary: After surveying the reasons for delayed extubation, the authors developed a scoring system to better predict the extubation success rate. This scoring system has promising potential in predicting extubation readiness and may help clinicians avoid delayed extubation and failed extubation-related health complications in neurosurgical patients.
Article
Engineering, Civil
M. Pari, A. V. Van de Graaf, M. A. N. Hendriks, J. G. Rots
Summary: In the finite element modelling of masonry structures, a numerically robust sequentially linear solution procedure and a suitable discretised tension-shear-compression failure model for interfaces are proposed to simulate the cracking-crushing-shearing failure possibilities in masonry. The applicability of these formulations are illustrated using 2D and 3D models in a pushover analysis on a squat unreinforced masonry wall, reproducing the experiment results in a stable manner.
ENGINEERING STRUCTURES
(2021)
Article
Medical Laboratory Technology
Danelle H. Moonen, Mindy Kohlhagen, Surendra Dasari, Maria A. Willrich, Taxiarchis Kourelis, Angela Dispenzieri, David L. Murray
Summary: This study explored the feasibility of using Matrix-assisted laser desorption ionization time of flight mass spectrometry coupled to immune enrichment (MASS-FIX) as an alternative to urine immunofixation electrophoresis (u-IFE). The results showed that u-MASS-FIX could reliably replace u-IFE and detect monoclonal proteins in urine that u-IFE failed to identify. Furthermore, u-MASS-FIX could also detect the mass and glycosylation of monoclonal proteins in urine, and it was performed using neat urine, which could potentially increase productivity by reducing labor minutes per test.
CLINICAL CHEMISTRY
(2023)
