RNA binding by Hfq and ring-forming (L)Sm proteins

Crystal structure and biochemical analysis of the heptameric Lsm1-7 complex

(2014) Lijun Zhou et al.   CELL RESEARCH

TAIL-seq: Genome-wide Determination of Poly(A) Tail Length and 3′ End Modifications

(2014) Hyeshik Chang et al.   MOLECULAR CELL

Hfq binds ribonucleotides in three different RNA-binding sites

(2013) Victoria Murina et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

RNA decay machines: Deadenylation by the Ccr4–Not and Pan2–Pan3 complexes

(2013) Elmar Wahle et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Lsm2 and Lsm3 bridge the interaction of the Lsm1-7 complex with Pat1 for decapping activation

(2013) Donghui Wu et al.   CELL RESEARCH

Targeted decay of a regulatory small RNA by an adaptor protein for RNase E and counteraction by an anti-adaptor RNA

(2013) Y. Gopel et al.   GENES & DEVELOPMENT

The role of disordered protein regions in the assembly of decapping complexes and RNP granules

(2013) S. Jonas et al.   GENES & DEVELOPMENT

The importance of regulatory RNAs in Staphylococcus aureus

(2013) Arnaud Tomasini et al.   INFECTION GENETICS AND EVOLUTION

Bacterial Small RNA-based Negative Regulation: Hfq and Its Accomplices

(2013) Nicholas De Lay et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mutations in Interaction Surfaces Differentially Impact E. coli Hfq Association with Small RNAs and Their mRNA Targets

(2013) Aixia Zhang et al.   JOURNAL OF MOLECULAR BIOLOGY

Positional Effects of AAN Motifs in rpoS Regulation by sRNAs and Hfq

(2013) Yi Peng et al.   JOURNAL OF MOLECULAR BIOLOGY

Crystal structures of the Lsm complex bound to the 3′ end sequence of U6 small nuclear RNA

(2013) Lijun Zhou et al.   NATURE

Uridylation prevents 3' trimming of oligoadenylated mRNAs

(2013) F. M. Sement et al.   NUCLEIC ACIDS RESEARCH

Mapping Hfq-RNA interaction surfaces using tryptophan fluorescence quenching

(2013) Kirsten E. Robinson et al.   NUCLEIC ACIDS RESEARCH

Conserved arginines on the rim of Hfq catalyze base pair formation and exchange

(2013) Subrata Panja et al.   NUCLEIC ACIDS RESEARCH

The interplay of Hfq, poly(A) polymerase I and exoribonucleases at the 3′ ends of RNAs resulting from Rho-independent termination

(2013) Philippe Régnier et al.   RNA Biology

Special Focus Hfq

(2013) Evelyn Sauer   RNA Biology

Licensing and due process in the turnover of bacterial RNA

(2013) Katarzyna J. Bandyra et al.   RNA Biology

Structure and RNA-binding properties of the bacterial LSm protein Hfq

(2013) Evelyn Sauer   RNA Biology

Archaeal and eukaryotic homologs of Hfq

(2013) Cameron Mura et al.   RNA Biology

Cycling of RNAs on Hfq

(2013) E. Gerhart H. Wagner   RNA Biology

Lsm proteins and Hfq

(2013) Carol J. Wilusz et al.   RNA Biology

Hfq binding changes the structure of Escherichia coli small noncoding RNAs OxyS and RprA, which are involved in the riboregulation of rpoS

(2013) C. A. Henderson et al.   RNA

Architecture of the Lsm1-7-Pat1 Complex: A Conserved Assembly in Eukaryotic mRNA Turnover

(2013) Humayun Sharif et al.   Cell Reports

RNA-binding Sm-like proteins of bacteria and archaea. Similarity and difference in structure and function

(2012) V. N. Murina et al.   BIOCHEMISTRY-MOSCOW

The Seed Region of a Small RNA Drives the Controlled Destruction of the Target mRNA by the Endoribonuclease RNase E

(2012) Katarzyna J. Bandyra et al.   MOLECULAR CELL

The low-resolution solution structure of Vibrio cholerae Hfq in complex with Qrr1 sRNA

(2012) Helen A. Vincent et al.   NUCLEIC ACIDS RESEARCH

Structural mechanism of Staphylococcus aureus Hfq binding to an RNA A-tract

(2012) Nicola Horstmann et al.   NUCLEIC ACIDS RESEARCH

Structural and Biochemical Studies on ATP Binding and Hydrolysis by the Escherichia coli RNA Chaperone Hfq

(2012) Hermann Hämmerle et al.   PLoS One

Small RNA binding to the lateral surface of Hfq hexamers and structural rearrangements upon mRNA target recognition

(2012) E. Sauer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The functional Hfq-binding module of bacterial sRNAs consists of a double or single hairpin preceded by a U-rich sequence and followed by a 3' poly(U) tail

(2012) H. Ishikawa et al.   RNA

The crucial role of PNPase in the degradation of small RNAs that are not associated with Hfq

(2012) J. M. Andrade et al.   RNA

Despite Similar Binding to the Hfq Protein Regulatory RNAs Widely Differ in Their Competition Performance

(2011) Mikołaj Olejniczak   BIOCHEMISTRY

Small RNA-induced mRNA degradation achieved through both translation block and activated cleavage

(2011) K. Prevost et al.   GENES & DEVELOPMENT

Cooperation of Escherichia coli Hfq hexamers in DsrA binding

(2011) W. Wang et al.   GENES & DEVELOPMENT

Competition among Hfq-binding small RNAs in Escherichia coli

(2011) Kyung Moon et al.   MOLECULAR MICROBIOLOGY

Structure of the spliceosomal U4 snRNP core domain and its implication for snRNP biogenesis

(2011) Adelaine K. W. Leung et al.   NATURE

Hfq and its constellation of RNA

(2011) Jörg Vogel et al.   NATURE REVIEWS MICROBIOLOGY

Structural insights into the dynamics and function of the C-terminus of the E. coli RNA chaperone Hfq

(2011) Mads Beich-Frandsen et al.   NUCLEIC ACIDS RESEARCH

Crystal structure of Hfq from Bacillus subtilis in complex with SELEX-derived RNA aptamer: insight into RNA-binding properties of bacterial Hfq

(2011) Tatsuhiko Someya et al.   NUCLEIC ACIDS RESEARCH

PolyU tail of rho-independent terminator of bacterial small RNAs is essential for Hfq action

(2011) Hironori Otaka et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structural basis for RNA 3′-end recognition by Hfq

(2011) Evelyn Sauer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Role of polynucleotide phosphorylase in sRNA function in Escherichia coli

(2011) N. De Lay et al.   RNA

Signals for pre-mRNA cleavage and polyadenylation

(2011) Bin Tian et al.   Wiley Interdisciplinary Reviews-RNA

Features and development ofCoot

(2010) P. Emsley et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

The role of Hfq in bacterial pathogens

(2010) Yanjie Chao et al.   CURRENT OPINION IN MICROBIOLOGY

The C-terminal α–α superhelix of Pat is required for mRNA decapping in metazoa

(2010) Joerg E Braun et al.   EMBO JOURNAL

Functional organization of the Sm core in the crystal structure of human U1 snRNP

(2010) Gert Weber et al.   EMBO JOURNAL

RNAs actively cycle on the Sm-like protein Hfq

(2010) A. Fender et al.   GENES & DEVELOPMENT

C-Terminally Truncated Derivatives of Escherichia coli Hfq Are Proficient in Riboregulation

(2010) Anders Steno Olsen et al.   JOURNAL OF MOLECULAR BIOLOGY

Recognition of heptameric seed sequence underlies multi-target regulation by RybB small RNA in Salmonella enterica

(2010) Roberto Balbontín et al.   MOLECULAR MICROBIOLOGY

Hfq binding at RhlB-recognition region of RNase E is crucial for the rapid degradation of target mRNAs mediated by sRNAs in Escherichia coli

(2010) Yoshiki Ikeda et al.   MOLECULAR MICROBIOLOGY

The primary transcriptome of the major human pathogen Helicobacter pylori

(2010) Cynthia M. Sharma et al.   NATURE

Genomic SELEX for Hfq-binding RNAs identifies genomic aptamers predominantly in antisense transcripts

(2010) C. Lorenz et al.   NUCLEIC ACIDS RESEARCH

Disruption of small RNA signaling caused by competition for Hfq

(2010) R. Hussein et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Evidence for an autonomous 5' target recognition domain in an Hfq-associated small RNA

(2010) K. Papenfort et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Deep sequencing of Salmonella RNA associated with heterologous Hfq proteins in vivo reveals small RNAs as a major target class and identifies RNA processing phenotypes

(2010) Alexandra Sittka et al.   RNA Biology

Lsm1-7-Pat1 complex:  A link between 3’ and 5’-ends in mRNA decay?

(2010) Sundaresan Tharun   RNA Biology

Bacterial Small RNA Regulators: Versatile Roles and Rapidly Evolving Variations

(2010) S. Gottesman et al.   Cold Spring Harbor Perspectives in Biology

Cyanobacteria contain a structural homologue of the Hfq protein with altered RNA-binding properties

(2009) Andreas Bøggild et al.   FEBS Journal

Crystal structure of human spliceosomal U1 snRNP at 5.5 Å resolution

(2009) Daniel A. Pomeranz Krummel et al.   NATURE

Decapping is preceded by 3′ uridylation in a novel pathway of bulk mRNA turnover

(2009) Olivia S Rissland et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Structure of Escherichia coli Hfq bound to polyriboadenylate RNA

(2009) T. M. Link et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

On the facultative requirement of the bacterial RNA chaperone, Hfq

(2009) Ambre Jousselin et al.   TRENDS IN MICROBIOLOGY

New ways to meet your (3') end oligouridylation as a step on the path to destruction

(2008) C. J. Wilusz et al.   GENES & DEVELOPMENT

Degradation of histone mRNA requires oligouridylation followed by decapping and simultaneous degradation of the mRNA both 5' to 3' and 3' to 5'

(2008) T. E. Mullen et al.   GENES & DEVELOPMENT

3'-cyclic phosphorylation of U6 snRNA leads to recruitment of recycling factor p110 through LSm proteins

(2008) K. Licht et al.   RNA

Deep Sequencing Analysis of Small Noncoding RNA and mRNA Targets of the Global Post-Transcriptional Regulator, Hfq

(2008) Alexandra Sittka et al.   PLoS Genetics