Macro lncRNAs

Intragenic Enhancers Act as Alternative Promoters

(2012) Monika S. Kowalczyk et al.   MOLECULAR CELL

Modular regulatory principles of large non-coding RNAs

(2012) Mitchell Guttman et al.   NATURE

RNA discrimination

(2012) Monika S. Kowalczyk et al.   NATURE

A Downstream CpG Island Controls Transcript Initiation and Elongation and the Methylation State of the Imprinted Airn Macro ncRNA Promoter

(2012) Martha V. Koerner et al.   PLoS Genetics

Genomic Imprinting: A Mammalian Epigenetic Discovery Model

(2011) Denise P. Barlow   Annual Review of Genetics

The majority of total nuclear-encoded non-ribosomal RNA in a human cell is 'dark matter' un-annotated RNA

(2011) Philipp Kapranov et al.   BMC BIOLOGY

Identification and resolution of artifacts in the interpretation of imprinted gene expression

(2011) C. Proudhon et al.   Briefings in Functional Genomics

Long Intergenic Noncoding RNAs: New Links in Cancer Progression

(2011) M.-C. Tsai et al.   CANCER RESEARCH

A Long Noncoding RNA Controls Muscle Differentiation by Functioning as a Competing Endogenous RNA

(2011) Marcella Cesana et al.   CELL

A ceRNA Hypothesis: The Rosetta Stone of a Hidden RNA Language?

(2011) Leonardo Salmena et al.   CELL

Biology and applications of small nucleolar RNAs

(2011) Tomaž Bratkovič et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Genomic imprinting: recognition and marking of imprinted loci

(2011) Lara K Abramowitz et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Depletion of Kcnq1ot1 non-coding RNA does not affect imprinting maintenance in stem cells

(2011) M. C. Golding et al.   DEVELOPMENT

Small RNAs in early mammalian development: from gametes to gastrulation

(2011) N. Suh et al.   DEVELOPMENT

Extra-embryonic-specific imprinted expression is restricted to defined lineages in the post-implantation embryo

(2011) Quanah J. Hudson et al.   DEVELOPMENTAL BIOLOGY

Antisense noncoding RNA promoter regulates the timing of de novo methylation of an imprinting control region

(2011) Natalia Guseva et al.   DEVELOPMENTAL BIOLOGY

Integrative annotation of human large intergenic noncoding RNAs reveals global properties and specific subclasses

(2011) M. N. Cabili et al.   GENES & DEVELOPMENT

Noncoding RNA gene silencing through genomic integration of RNA destabilizing elements using zinc finger nucleases

(2011) T. Gutschner et al.   GENOME RESEARCH

Accurate identification of A-to-I RNA editing in human by transcriptome sequencing

(2011) J. H. Bahn et al.   GENOME RESEARCH

Re-investigation and RNA sequencing-based identification of genes with placenta-specific imprinted expression

(2011) Hiroaki Okae et al.   HUMAN MOLECULAR GENETICS

Recurrence and variability of germline EPCAM deletions in Lynch syndrome

(2011) Roland P. Kuiper et al.   HUMAN MUTATION

Role of Noncoding RNA ANRIL in Genesis of Plexiform Neurofibromas in Neurofibromatosis Type 1

(2011) Eric Pasmant et al.   JNCI-Journal of the National Cancer Institute

lincRNAs act in the circuitry controlling pluripotency and differentiation

(2011) Mitchell Guttman et al.   NATURE

Targeted RNA sequencing reveals the deep complexity of the human transcriptome

(2011) Tim R Mercer et al.   NATURE BIOTECHNOLOGY

Transcriptome sequencing across a prostate cancer cohort identifies PCAT-1, an unannotated lincRNA implicated in disease progression

(2011) John R Prensner et al.   NATURE BIOTECHNOLOGY

Genomic imprinting: the emergence of an epigenetic paradigm

(2011) Anne C. Ferguson-Smith   NATURE REVIEWS GENETICS

Gene silencing in X-chromosome inactivation: advances in understanding facultative heterochromatin formation

(2011) Anton Wutz   NATURE REVIEWS GENETICS

Non-coding RNAs as regulators of embryogenesis

(2011) Andrea Pauli et al.   NATURE REVIEWS GENETICS

Gracefully ageing at 50, X-chromosome inactivation becomes a paradigm for RNA and chromatin control

(2011) Jeannie T. Lee   NATURE REVIEWS MOLECULAR CELL BIOLOGY

An RNA-Seq Strategy to Detect the Complete Coding and Non-Coding Transcriptome Including Full-Length Imprinted Macro ncRNAs

(2011) Ru Huang et al.   PLoS One

RNAi-mediated knockdown of Xist can rescue the impaired postimplantation development of cloned mouse embryos

(2011) S. Matoba et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

RNAcentral: A vision for an international database of RNA sequences

(2011) A. Bateman et al.   RNA

The Reality of Pervasive Transcription

(2011) Michael B. Clark et al.   PLOS BIOLOGY

Uncoupling Antisense-Mediated Silencing and DNA Methylation in the Imprinted Gnas Cluster

(2011) Christine M. Williamson et al.   PLoS Genetics

Structural and Functional Differences in the Long Non-Coding RNA Hotair in Mouse and Human

(2011) Patrick Schorderet et al.   PLoS Genetics

Prader-Willi syndrome and Angelman syndrome

(2010) Karin Buiting   AMERICAN JOURNAL OF MEDICAL GENETICS PART C-SEMINARS IN MEDICAL GENETICS

Russell-Silver syndrome

(2010) Thomas Eggermann   AMERICAN JOURNAL OF MEDICAL GENETICS PART C-SEMINARS IN MEDICAL GENETICS

Beckwith-Wiedemann syndrome

(2010) Sanaa Choufani et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART C-SEMINARS IN MEDICAL GENETICS

ANRIL Expression Is Associated With Atherosclerosis Risk at Chromosome 9p21

(2010) Lesca M. Holdt et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Long Noncoding RNAs with Enhancer-like Function in Human Cells

(2010) Ulf Andersson Ørom et al.   CELL

Genomic imprinting mechanisms in embryonic and extraembryonic mouse tissues

(2010) Q J Hudson et al.   HEREDITY

Risk of colorectal and endometrial cancers in EPCAM deletion-positive Lynch syndrome: a cohort study

(2010) Marlies JE Kempers et al.   LANCET ONCOLOGY

Nuclear Organization and Dynamics of 7SK RNA in Regulating Gene Expression

(2010) Kannanganattu V. Prasanth et al.   MOLECULAR BIOLOGY OF THE CELL

Molecular Interplay of the Noncoding RNA ANRIL and Methylated Histone H3 Lysine 27 by Polycomb CBX7 in Transcriptional Silencing of INK4a

(2010) Kyoko L. Yap et al.   MOLECULAR CELL

Long non-coding RNA HOTAIR reprograms chromatin state to promote cancer metastasis

(2010) Rajnish A. Gupta et al.   NATURE

Targeted deletion of the 9p21 non-coding coronary artery disease risk interval in mice

(2010) Axel Visel et al.   NATURE

Transcript assembly and quantification by RNA-Seq reveals unannotated transcripts and isoform switching during cell differentiation

(2010) Cole Trapnell et al.   NATURE BIOTECHNOLOGY

Ab initio reconstruction of cell type–specific transcriptomes in mouse reveals the conserved multi-exonic structure of lincRNAs

(2010) Mitchell Guttman et al.   NATURE BIOTECHNOLOGY

Large intergenic non-coding RNA-RoR modulates reprogramming of human induced pluripotent stem cells

(2010) Sabine Loewer et al.   NATURE GENETICS

Genome-wide association study identifies five new breast cancer susceptibility loci

(2010) Clare Turnbull et al.   NATURE GENETICS

Long non-coding RNA ANRIL is required for the PRC2 recruitment to and silencing of p15 INK4B tumor suppressor gene

(2010) Y Kotake et al.   ONCOGENE

Dampening DNA binding: A common mechanism of transcriptional repression for both ncRNAs and protein domains

(2010) James A. Goodrich et al.   RNA Biology

Spliceosome Structure and Function

(2010) C. L. Will et al.   Cold Spring Harbor Perspectives in Biology

TopHat: discovering splice junctions with RNA-Seq

(2009) Cole Trapnell et al.   BIOINFORMATICS

The function of non-coding RNAs in genomic imprinting

(2009) M. V. Koerner et al.   DEVELOPMENT

Long noncoding RNAs: functional surprises from the RNA world

(2009) J. E. Wilusz et al.   GENES & DEVELOPMENT

Chromatin signature reveals over a thousand highly conserved large non-coding RNAs in mammals

(2009) Mitchell Guttman et al.   NATURE

New common variants affecting susceptibility to basal cell carcinoma

(2009) Simon N Stacey et al.   NATURE GENETICS

Genome-wide association study identifies five susceptibility loci for glioma

(2009) Sanjay Shete et al.   NATURE GENETICS

Long non-coding RNAs: insights into functions

(2009) Tim R. Mercer et al.   NATURE REVIEWS GENETICS

Relationship between CAD Risk Genotype in the Chromosome 9p21 Locus and Gene Expression. Identification of Eight New ANRIL Splice Variants

(2009) Lasse Folkersen et al.   PLoS One

Many human large intergenic noncoding RNAs associate with chromatin-modifying complexes and affect gene expression

(2009) Ahmad M. Khalil et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Efficient oligonucleotide-mediated degradation of nuclear noncoding RNAs in mammalian cultured cells

(2009) T. Ideue et al.   RNA

Polycomb Group Proteins Ezh2 and Rnf2 Direct Genomic Contraction and Imprinted Repression in Early Mouse Embryos

(2008) Rémi Terranova et al.   DEVELOPMENTAL CELL

Silencing and transcriptional properties of the imprinted Airn ncRNA are independent of the endogenous promoter

(2008) Stefan H Stricker et al.   EMBO JOURNAL

Identification of the human homolog of the imprinted mouse Air non-coding RNA

(2008) Iveta Y. Yotova et al.   GENOMICS

Kcnq1ot1 Antisense Noncoding RNA Mediates Lineage-Specific Transcriptional Silencing through Chromatin-Level Regulation

(2008) Radha Raman Pandey et al.   MOLECULAR CELL

Promoter-driven splicing regulation in fission yeast

(2008) Alberto Moldón et al.   NATURE

Epigenetic silencing of tumour suppressor gene p15 by its antisense RNA

(2008) Wenqiang Yu et al.   NATURE

Heritable somatic methylation and inactivation of MSH2 in families with Lynch syndrome due to deletion of the 3′ exons of TACSTD1

(2008) Marjolijn J L Ligtenberg et al.   NATURE GENETICS

An Epigenetic Role for Maternally Inherited piRNAs in Transposon Silencing

(2008) J. Brennecke et al.   SCIENCE

Divergent Transcription from Active Promoters

(2008) Amy C. Seila et al.   SCIENCE

The Air Noncoding RNA Epigenetically Silences Transcription by Targeting G9a to Chromatin

(2008) T. Nagano et al.   SCIENCE

A Global View of Gene Activity and Alternative Splicing by Deep Sequencing of the Human Transcriptome

(2008) M. Sultan et al.   SCIENCE