期刊
RHEUMATOLOGY INTERNATIONAL
卷 31, 期 6, 页码 841-842出版社
SPRINGER HEIDELBERG
DOI: 10.1007/s00296-010-1485-3
关键词
Systemic sclerosis; Scleroderma; Rituximab; Interstitial lung disease; B cells; Fibrosis; Skin thickening; Rheumatic diseases
类别
Several lines of evidence from basic research indicate that B cells may contribute to the pathogenesis of systemic sclerosis. Clinical studies as well have provided preliminary data pointing to the direction that B-cell depletion with rituximab might be a therapeutic option for patients with this debilitating disease.
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