TLR2/TLR4-dependent exaggerated cytokine production in hyperimmunoglobulinaemia D and periodic fever syndrome

Defects in Mitochondrial Clearance Predispose Human Monocytes to Interleukin-1β Hypersecretion

(2013) Robert van der Burgh et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mutations in the Mevalonate Kinase ( MVK ) Gene Cause Nonsyndromic Retinitis Pigmentosa

(2013) Anna M. Siemiatkowska et al.   OPHTHALMOLOGY

Mevalonate kinase deficiency nomenclature

(2013) Monique Stoffels et al.   RHEUMATOLOGY INTERNATIONAL

Sustained efficacy of the monoclonal anti-interleukin-1 beta antibody canakinumab in a 9-month trial in Schnitzler's syndrome

(2012) Heleen D de Koning et al.   ANNALS OF THE RHEUMATIC DISEASES

Exome sequencing identifies MVK mutations in disseminated superficial actinic porokeratosis

(2012) Sheng-Quan Zhang et al.   NATURE GENETICS

Treating inflammation by blocking interleukin-1 in a broad spectrum of diseases

(2012) Charles A. Dinarello et al.   NATURE REVIEWS DRUG DISCOVERY

On-demand anakinra treatment is effective in mevalonate kinase deficiency

(2011) E. J. Bodar et al.   ANNALS OF THE RHEUMATIC DISEASES

Hyper-IgD syndrome or mevalonate kinase deficiency

(2011) Monique Stoffels et al.   CURRENT OPINION IN RHEUMATOLOGY

The inhibition of mevalonate pathway induces upregulation of NALP3 expression: new insight in the pathogenesis of mevalonate kinase deficiency

(2010) Alessandra Pontillo et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

Endogenous toll-like receptor ligands and their biological significance

(2010) Li Yu et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Compromized geranylgeranylation of RhoA and Rac1 in mevalonate kinase deficiency

(2010) L. Henneman et al.   JOURNAL OF INHERITED METABOLIC DISEASE

Targeting farnesyl-transferase as a novel therapeutic strategy for mevalonate kinase deficiency: In vitro and in vivo approaches

(2010) Luigina De Leo et al.   PHARMACOLOGICAL RESEARCH

HMG-CoA reductase inhibition induces IL-1  release through Rac1/PI3K/PKB-dependent caspase-1 activation

(2008) L. M. Kuijk et al.   BLOOD

Statin synergizes with LPS to induce IL-1β release by THP-1 cells through activation of caspase-1

(2008) Loes M. Kuijk et al.   MOLECULAR IMMUNOLOGY