Lithium protects cartilage from cytokine-mediated degradation by reducing collagen-degrading MMP production via inhibition of the P38 mitogen-activated protein kinase pathway

Evaluation of the efficacy and safety of pamapimod, a p38 MAP kinase inhibitor, in a double-blind, methotrexate-controlled study of patients with active rheumatoid arthritis

(2009) Stanley B. Cohen et al.   ARTHRITIS AND RHEUMATISM

Efficacy, pharmacodynamics, and safety of VX-702, a novel p38 MAPK inhibitor, in rheumatoid arthritis: Results of two randomized, double-blind, placebo-controlled clinical studies

(2009) Nemanja Damjanov et al.   ARTHRITIS AND RHEUMATISM

Inhibition of p38: Has the fat lady sung?

(2009) Mark C. Genovese   ARTHRITIS AND RHEUMATISM

Proteinases involved in matrix turnover during cartilage and bone breakdown

(2009) Tim E. Cawston et al.   CELL AND TISSUE RESEARCH

Enhanced Endothelial Cell Senescence by Lithium-induced Matrix Metalloproteinase-1 Expression

(2009) Ian T. Struewing et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Differential Toll-like receptor-dependent collagenase expression in chondrocytes

(2008) Q Zhang et al.   ANNALS OF THE RHEUMATIC DISEASES

Shared Principles in NF-κB Signaling

(2008) Matthew S. Hayden et al.   CELL

P38 MAP kinase inhibitors as potential therapeutics for the treatment of joint degeneration and pain associated with osteoarthritis

(2008) Kimberly K Brown et al.   Journal of Inflammation-London

Mitogen-activated protein kinase-activated protein kinase 2 (MK2) modulates key biological pathways associated with OA disease pathology

(2008) S.W. Jones et al.   OSTEOARTHRITIS AND CARTILAGE

A role for a lithium-inhibited Golgi nucleotidase in skeletal development and sulfation

(2008) J. P. Frederick et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Deciphering the lithium transcriptome: Microarray profiling of lithium-modulated gene expression in human neuronal cells

(2007) R.S. Seelan et al.   NEUROSCIENCE