Article
Medicine, General & Internal
Tom A. A. Doyle, Colin M. E. Halverson
Summary: Patients with hypermobile Ehlers-Danlos Syndrome (hEDS) commonly use complementary and alternative medical (CAM) techniques, with massage therapy, medical cannabis, and mindfulness being considered the most useful CAM modalities for symptom management. Patients trust CAM modalities and practitioners more than conventional medical providers, but also express skepticism and recount instances of harm caused by both CAM and conventional therapies.
FRONTIERS IN MEDICINE
(2022)
Article
Medicine, General & Internal
Marco Paoloni, Francesco Agostini, Sergio Bernasconi, Gianni Bona, Carlo Cisari, Massimo Fioranelli, Marco Invernizzi, Antonello Madeo, Marco Matucci-Cerinic, Alberto Migliore, Nicola Quirino, Carlo Ventura, Roberto Vigano, Andrea Bernetti
Summary: This paper conducted a Delphi consensus to investigate the opinions of Italian physicians on the use of CAM in clinical practice. The results showed consensus on various topics, including indications and safety issues. The conclusion is that combining CAM with conventional medicines is safe for treating non-critical medical conditions.
MEDICINA-LITHUANIA
(2022)
Article
Agriculture, Dairy & Animal Science
Petra Weiermayer, Michael Frass, Thomas Peinbauer, Liesbeth Ellinger, Edward De Beukelaer
Summary: Individualized homeopathic therapy, based on the selection of the simile, shows effectiveness in high-quality studies. The integration of homeopathy in veterinary medicine and university teaching is necessary for patient care and is supported by legal regulations and consensus guidelines in Switzerland and the United States.
Article
Pediatrics
Angharad Vernon-Roberts, Abida Denny, Andrew S. Day
Summary: This study investigated the use of complementary or alternative medicine (CAM) among children in a tertiary care hospital in New Zealand. It found that 56% of the children used CAM, with oral supplements, body manipulation methods, and holistic practices being the most common. CAM use was associated with lower child health rating, Maori ethnicity, parent education level, and family member CAM use. The study also revealed that parental opinion and doctor recommendation were important factors influencing CAM use, and only 31% of the CAM use was disclosed to the child's medical team.
Article
Clinical Neurology
Benedicte Marie Finger, Annika Triller, Ashley M. Bourke, Gert Jan Lammers, Christian Veauthier, Merve Yildizli, Ulf Kallweit
Summary: This study investigated the frequency and characteristics of complementary and alternative medicine (CAM) use in German narcolepsy patients. 15% of patients were using CAM at the time of the survey, and an additional 18% reported past use. The most commonly used CAM treatments were vitamins/trace elements, homeopathy, and meditation. CAM users were more likely to experience side effects from medication and have low adherence to pharmacological treatment.
Article
Agriculture, Dairy & Animal Science
Anna Bergh, Irene Lund, Anna Bostrom, Heli Hyytiainen, Kjell Asplund
Summary: This study reviewed the scientific literature of 24 different complementary and alternative veterinary medicine (CAVM) therapies used in cats, dogs, and horses, and found that there is insufficient scientific documentation to draw clear conclusions about their clinical effect. The research assessed 42 eligible publications representing nine different CAVM therapies, with varying levels of bias and reported treatment effects. Further research is needed to better understand the efficacy of these CAVM therapies.
Article
Multidisciplinary Sciences
Ines Stanossek, Axel Wehrend
Summary: This study provides German data on the use of naturopathy and complementary medicine in small animal science. Despite potential biases from voluntary participation, the study shows a wide range of applications for various indications. Homeopathy was most frequently mentioned as a treatment option with potential disadvantages. However, it is also the most commonly used treatment option in this study. The study supports the need for a discussion about evidence, regulations, and qualifications due to the widespread use of naturopathy and complementary medicine in veterinary practice. More data on effectiveness and mode of action are needed to enable evidence-based advice for pet owners.
Review
Rheumatology
Paraschou Vasileios, Partalidou Styliani, Gkekas Nifon, Siolos Pavlos, Fotiadis Aris, Pantekidis Ioannis
Summary: Fibromyalgia is a chronic medical condition characterized by chronic pain and additional symptoms such as depression, anxiety, and insomnia. Traditional pharmaceutical management has been the main treatment approach, but in recent years, low-impact aerobic exercise and complementary and alternative medical (CAM) exercise have shown potential benefits. A meta-analysis of 14 studies involving 886 patients found that CAM exercise had a positive effect on patients' Fibromyalgia Impact Questionnaire score, with dance and Tai chi showing particularly promising results.
RHEUMATOLOGY INTERNATIONAL
(2022)
Review
Pharmacology & Pharmacy
Hongmin Chu, Seunghwan Moon, Jeongsu Park, Seongjun Bak, Youme Ko, Bo-Young Youn
Summary: The development of artificial intelligence in complementary and alternative medicine has been rapidly advancing. This systematic scoping review identified three main categories of AI usage in CAM, including acupuncture treatment, tongue and lip diagnoses, and herbal medicine. Future research should focus on verifying and validating these AI models through large-scale clinical trials.
FRONTIERS IN PHARMACOLOGY
(2022)
Review
Medicine, General & Internal
Jin Young Yoon, Seok-Jae Ko, Jae-Woo Park, Jae Myung Cha
Summary: Many Asian patients with functional dyspepsia (FD) are unsatisfied with conventional medical treatment and are seeking complementary and alternative medicine (CAM) therapies. However, there is limited research on CAM for FD specifically in an Asian context. Traditional herbal formulas, STW-5, peppermint and caraway, FDgard, black seed oil, and psychotherapy have been used in FD patients, but the evidence supporting their effectiveness is weak. Well-planned, large-scale studies are needed to evaluate the efficacy of CAM in treating FD, especially in Asian countries.
Article
Dermatology
Kyla N. Price, Erin K. Collier, Tristan Grogan, Jennifer M. Fernandez, Raed Alhusayen, Afsaneh Alavi, Iltefat H. Hamzavi, Michelle A. Lowes, Martina J. Porter, Jennifer L. Hsiao, Vivian Y. Shi
Summary: Recent studies have shown a widespread use of complementary and alternative medicine (CAM) among patients with HS. Providers vary in their comfort and opinions regarding CAM, with most agreeing that CAM and conventional medicine are more effective together, while citing a lack of scientific evidence as a barrier to recommending CAM.
DERMATOLOGIC THERAPY
(2021)
Article
Public, Environmental & Occupational Health
Seyed Hamdollah Mosavat, Mehdi Pasalar, Hassan Joulaei, Vira Ameli, Seyed Taghi Heydari, Ali Mirzazadeh, Mohammad Hashem Hashempur
Summary: This study examines the frequency and reasons behind the use of complementary and alternative medicine (CAM) among people living with HIV in Shiraz, Iran. The results show that the majority of participants use CAM, and there is no significant difference in quality of life between those who use CAM and those who do not.
FRONTIERS IN PUBLIC HEALTH
(2023)
Review
Clinical Neurology
Panagiotis Kerezoudis, Evangelia N. Kerezoudi, Abdurehman Choudhry, Benjamin T. Himes, Ian F. Parney
Summary: Many patients and caregivers of glioma seek CAM methods to comfort themselves and cope with cancer medication side effects. This study summarizes the existing evidence on the safety and efficacy of CAM treatments for gliomas.
Article
Computer Science, Interdisciplinary Applications
Mike Thelwall
Summary: This article evaluates the citation impact of four CAMs in academic community, finding that acupuncture, chiropractic, and homeopathy are exceptions with higher citation rates in some fields such as Medicine, Nursing, Health Professions, and Neuroscience.
Article
Oncology
Nazi Nejat, Amir Rahbarian, Fatemeh Mehrabi, Fatemeh Rafiei
Summary: This study investigated the prevalence of complementary and alternative medicine (CAM) use among cancer patients in Iran. The findings showed that 44.3% of the 320 participants were using CAM. Most patients used CAM to improve their physical condition and used it alongside conventional medical treatments. Common CAM treatments included visiting holy places, practicing yoga, engaging in prayer therapy, and using medicinal plants and special diets.
JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY
(2023)
Article
Dentistry, Oral Surgery & Medicine
Neerav Goyal, Max Hennessy, Erik Lehman, Wenxue Lin, Antonio Agudo, Wolfgang Ahrens, Stefania Boccia, Paul Brennan, Hermann Brenner, Gabriella Cadoni, Cristina Canova, Chu Chen, David Conway, Maria Paula Curado, Luigino Dal Maso, Alexander W. Daudt, Valeria Edefonti, Eleonora Fabianova, Leticia Fernandez, Silvia Franceschi, Werner Garavello, Maura Gillison, Richard B. Hayes, Claire Healy, Rolando Herrero, Ivana Holcatova, Jossy L. Kanda, Karl Kelsey, Bo T. Hansen, Rosalina Koifman, Pagona Lagiou, Carlo La Vecchia, Fabio Levi, Guojun Li, Jolanta Lissowska, Rossana Mendoza Lopez, Daniele Luce, Gary Macfarlane, Dana Mates, Keitaro Matsuo, Michael McClean, Ana Menezes, Gwenn Menvielle, Hal Morgenstern, Kirsten Moysich, Eva Negri, Andrew F. Olshan, Tamas Pandics, Jerry Polesel, Mark Purdue, Loredana Radoi, Heribert Ramroth, Lorenzo Richiardi, Stimson Schantz, Stephen M. Schwartz, Diego Serraino, Oxana Shangina, Elaine Smith, Erich M. Sturgis, Beata Swiatkowska, Peter Thomson, Thomas L. Vaughan, Marta Vilensky, Deborah M. Winn, Victor Wunsch-Filho, Guo-Pei Yu, Jose P. Zevallos, Zuo-Feng Zhang, Tongzhang Zheng, Ariana Znaor, Paolo Boffetta, Mia Hashibe, Yuan-Chin A. Lee, Joshua E. Muscat
Summary: This study analyzed the relationship between cigarette smoking, alcohol consumption, and head and neck cancer risk factors in less developed and more developed countries. The results showed that the duration of smoking and alcohol consumption had different effects on the risk of specific cancer sites depending on the country's level of development. These findings suggest that the degree of industrialization and economic development affects the relationship between smoking, alcohol, and head and neck cancer.
Article
Rheumatology
Gary J. Macfarlane, Renke Biallas, Linda E. Dean, Gareth T. Jones, Nicola J. Goodson, Ovidiu Rotariu
Summary: Among patients with axSpA, biologic therapies were associated with an increased risk of IBD compared to other therapies, based on observational studies. However, this association was not observed in placebo-controlled RCTs. Furthermore, the data did not suggest a higher risk of IBD with ETN compared to other anti-TNF therapies.
JOURNAL OF RHEUMATOLOGY
(2023)
Article
Oncology
Sanjeev Budhathoki, Brenda Diergaarde, Geoffrey Liu, Andrew Olshan, Andrew Ness, Tim Waterboer, Shama Virani, Patricia Basta, Noemi Bender, Nicole Brenner, Tom Dudding, Neil Hayes, Andrew Hope, Shao Hui Huang, Katrina Hueniken, Beatriz Kanterewicz, James D. McKay, Miranda Pring, Steve Thomas, Kathy Wisniewski, Sera Thomas, Yonathan Brhane, Antonio Agudo, Laia Alemany, Areti Lagiou, Luigi Barzan, Cristina Canova, David I. Conway, Claire M. Healy, Ivana Holcatova, Pagona Lagiou, Gary J. Macfarlane, Tatiana V. Macfarlane, Jerry Polesel, Lorenzo Richiardi, Max Robinson, Ariana Znaor, Paul Brennan, Rayjean J. Hung
Summary: To aid early detection of head and neck cancer, a risk prediction model based on demographic and lifestyle factors, HPV serological markers, and genetic markers has been developed. The risk models showed reasonable predictive accuracy for overall head and neck cancer, and substantially improved accuracy for oropharyngeal cancer when including HPV serology. These models may be helpful for identifying high-risk individuals.
INTERNATIONAL JOURNAL OF CANCER
(2023)
Letter
Rheumatology
Daniel J. Clauw, Ernest H. S. Choy, Vitaly Napadow, Anushka Soni, Kevin F. Boehnke, Bruce Naliboff, Afton L. Hassett, Anne Arewasikporn, Andrew Schrepf, Chelsea M. Kaplan, David Williams, Neil Basu, Rachel S. Bergmans, Richard E. Harris, Steven E. Harte, Andrea Chadwick, Gary J. Macfarlane
NATURE REVIEWS RHEUMATOLOGY
(2023)
Article
Public, Environmental & Occupational Health
K. Walker-Bone, G. J. Macfarlane, K. Burton, A. M. McConnachie, R. Zhang, G. T. Jones
Summary: Arm pain is a common problem in the workplace. Advicing workers to keep using their arms as much as possible leads to less disability at 6 months, especially for those who lift heavy weights or believe work caused their symptoms. Early physiotherapy, however, made no difference to disability outcomes. Similar results were seen amongst workers diagnosed with lateral epicondylitis.
OCCUPATIONAL MEDICINE-OXFORD
(2023)
Review
Anesthesiology
Christopher Eccleston, Emma Begley, Hollie Birkinshaw, Ernest Choy, Geert Crombez, Emma Fisher, Anna Gibby, Rachael Gooberman-Hill, Sharon Grieve, Amber Guest, Abbie Jordan, Amanda Lilywhite, Gary J. Macfarlane, Candida McCabe, John McBeth, Anthony E. Pickering, Tamar Pincus, Hannah M. Sallis, Samantha Stone, Danielle Van der Windt, Diego Vitali, Elaine Wainwright, Colin Wilkinson, Amanda C. de C. Williams, Anica Zeyen, Edmund Keogh
Article
Rheumatology
Louise Linde, Lykke M. Ornbjerg, Stylianos Georgiadis, Simon H. Rasmussen, Ulf Lindstrom, Johan Askling, Brigitte Michelsen, Daniela Di Giuseppe, Johan K. Wallman, Bjorn Gudbjornsson, Thorvardur Jon Love, Dan C. Nordstrom, Timo Yli-Kerttula, Lucie Nekvindova, Jiri Vencovsky, Florenzo Iannone, Alberto Cauli, Anne Gitte Loft, Bente Glintborg, Karin Laas, Ziga Rotar, Matija Tomsic, Gary J. Macfarlane, Burkhard Moller, Marleen van de Sande, Catalin Codreanu, Michael J. Nissen, Merih Birlik, Sukran Erten, Maria J. Santos, Elsa Vieira-Sousa, Merete L. Hetland, Mikkel Ostergaard
Summary: In bio-naive patients with PsA initiating a TNF inhibitor (TNFi), baseline predictors of Disease Activity index for PsA in 28 joints (DAPSA28) remission and moderate response at 6 months, as well as drug retention at 12 months were identified, indicating potential generalizability from country to disease level.
Article
Rheumatology
Huey Yi Chong, Paul McNamee, Eva-Maria Bachmair, Kathryn Martin, Lorna Aucott, Neeraj Dhaun, Emma Dures, Richard Emsley, Stuart. R. Gray, Elizabeth Kidd, Vinod Kumar, Karina Lovell, Graeme MacLennan, John Norrie, Lorna Paul, Jonathan Packham, Stuart. H. Ralston, Stefan Siebert, Alison Wearden, Gary Macfarlane, Neil Basu
Summary: This study estimated the cost-effectiveness of combining cognitive behavioural approach (CBA) or personalized exercise programme (PEP) with usual care (UC) for patients with inflammatory rheumatic diseases and chronic, moderate to severe fatigue. The results showed that PEP was more expensive but significantly more effective than UC, while CBA was more expensive but not significantly more effective. Therefore, combining PEP with UC is likely to be a cost-effective use of healthcare resources.
Letter
Rheumatology
Burak Kundakci, Michelle Hall, Fabiola Atzeni, Jaime Branco, Dan Buskila, Daniel Clauw, Leslie J. Crofford, Mary-Ann Fitzcharles, Vasileios Georgopoulos, Robert D. Gerwin, Eva Kosek, Gary J. Macfarlane, Caroline Neal, Nathan J. Rudin, Sarah Ryan, Jose A. P. da Silva, Ann M. Taylor, Dennis C. Turk, Daniel Whibley, Michael Doherty, Weiya Zhang, Abhishek Abhishek
SEMINARS IN ARTHRITIS AND RHEUMATISM
(2023)
Article
Public, Environmental & Occupational Health
Kathryn R. Martin, Kevin Stelfox, Gary J. Macfarlane, Paul McNamee, Zoe Morrison, Toby O. Smith, Walk Ease Res Study Team Walk Ease Res Study Team
Summary: Walk With Ease (WWE) is a popular walking programme in the USA that has been proven to increase physical activity and improve arthritis symptoms. The researchers wanted to introduce WWE to the UK and found that it was well-received and beneficial for the participants. WWE has great potential to improve health and well-being in the UK.
TRANSLATIONAL BEHAVIORAL MEDICINE
(2023)
Article
Neurosciences
Georgios Baskozos, Harry L. Hebert, Mathilde M. V. Pascal, Andreas C. Themistocleous, Gary J. Macfarlane, David Wynick, David L. H. Bennett, Blair H. Smith
Summary: This study is the largest epidemiological investigation of neuropathic pain so far. The findings confirm that this disorder is common in middle- to older-aged individuals with various causes and has a greater impact on health compared to non-neuropathic pain.
Article
Oncology
Johannes M. A. Kusters, Brenda Diergaarde, Andrew Ness, Maarten F. Schim van der Loeff, Janneke C. M. Heijne, Lea Schroeder, Katrina Hueniken, James D. McKay, Gary J. Macfarlane, Pagona Lagiou, Areti Lagiou, Jerry Polesel, Antonio Agudo, Laia Alemany, Wolfgang Ahrens, Claire M. Healy, David I. Conway, Max Robinson, Christina Canova, Ivana Holcatova, Lorenzo Richiardi, Ariana Znaor, Miranda Pring, Steve Thomas, D. Neil Hayes, Geoffrey Liu, Rayjean J. Hung, Paul Brennan, Andrew F. Olshan, Shama Virani, Tim Waterboer
Summary: An increasing proportion of head and neck cancer, particularly oropharyngeal cancer, is caused by HPV. This study examined the diagnostic accuracy of HPV serology and its performance across patient characteristics. The results showed that HPV serology is a robust biomarker for HPV-driven OPC, with consistent diagnostic accuracy across sex and different age groups.
INTERNATIONAL JOURNAL OF CANCER
(2023)
Article
Geriatrics & Gerontology
Anna Zajacova, Alvaro Pereira Filho, Merita Limani, Hanna Grol-Prokopczyk, Zachary Zimmer, Dmitry Scherbakov, Roger B. Fillingim, Mark D. Hayward, Ian Gilron, Gary J. Macfarlane, Cary Reid
Summary: The study evaluated pain treatment types among community-dwelling adults in the United States and Canada, finding that over-the-counter medication, living with pain, and exercise were commonly used methods. Pain was the most salient correlate for all pain treatments, while country differences were generally small. Individual were grouped into distinct clusters based on their preferred treatment methods.
INNOVATION IN AGING
(2023)
Letter
Medicine, Research & Experimental
Gary J. Macfarlane, Marcus Beasley, Gareth T. Jones
JOURNAL OF CLINICAL INVESTIGATION
(2023)
Article
Rheumatology
Louise Linde, Lykke M. Ornbjerg, Simon H. Rasmussen, Thorvardur Jon Love, Anne Gitte Loft, Jakub Zavada, Jiri Vencovsky, Karin Laas, Dan Nordstrom, Tuulikki Sokka-Isler, Bjorn Gudbjornsson, Gerdur Grondal, Florenzo Iannone, Roberta Ramonda, Pasoon Hellamand, Eirik K. Kristianslund, Tore K. Kvien, Ana M. Rodrigues, Maria J. Santos, Catalin Codreanu, Ziga Rotar, Matija Tomsic, Isabel Castrejon, Federico Diaz-Gonzales, Daniela Di Giuseppe, Lotta Ljung, Michael J. Nissen, Adrian Ciurea, Gary J. Macfarlane, Maureen Heddle, Bente Glintborg, Mikkel Ostergaard, Merete L. Hetland
Summary: This study investigates the differences and commonalities in the set-up, data collection, and patient-reported outcome measures (PROMs) in European clinical registries for axial spondyloarthritis (axSpA) and psoriatic arthritis (PsA). The study finds significant heterogeneity in registry design and data collection, but an increase in data completeness of PROMs in recent years. These findings may impact the results of collaborative research in the future.
ARTHRITIS RESEARCH & THERAPY
(2023)