Article
Infectious Diseases
Delveen R. Ibrahim, Christine E. R. Dodd, Dov J. Stekel, Remilekun T. Meshioye, Mathew Diggle, Michelle Lister, Jon L. Hobman
Summary: Cephalosporin therapy failure is a serious problem worldwide for infection control. Cephalosporin-resistant infections are often caused by multidrug-resistant E. coli producing ESBLs and/or pAmpC beta-lactamases. Analysis of MDR E. coli isolates from a UK hospital revealed a high prevalence of ESBL/pAmpC genetic determinants and significant correlations between resistance genes and specific antibiotics. The findings emphasize the importance of improved antibiotic therapy guidelines, including reduced usage and enhanced surveillance.
Article
Immunology
Qiang Zhao, Yueyun Shen, Gang Chen, Yanping Luo, Shenghui Cui, Yaping Tian
Summary: The study analyzed the drug resistance prevalence and genetic characteristics of fecal E. coli isolated from healthy children at a kindergarten in Beijing, China. The results showed high resistance to multiple antibiotics and observed clonal spread of certain prevalent sequence types among the isolates. The findings highlight the seriousness of multidrug resistance and potential pathogenicity of E. coli in healthy children, emphasizing the need for increased surveillance and control measures.
FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY
(2021)
Article
Environmental Sciences
Pedro Rueda Furlan, Eliana Guedes Stehling
Summary: This study identified pathogenic E. coli in soils resistant to beta-lactams, fluoroquinolones, and colistin, highlighting the potential risk of contamination to the surrounding environments and food, increasing the exposure risk to humans and animals.
ENVIRONMENTAL POLLUTION
(2021)
Article
Immunology
Zhihai Liu, Ke Wang, Yaru Zhang, Lining Xia, Li Zhao, Changmei Guo, Xudong Liu, Liting Qin, Zhihui Hao
Summary: The study aimed to understand the diversity characteristics of ESBL-producing Escherichia coli (ESBL-EC) in chicken, pig, and cattle. The results showed a high prevalence of ESBL-EC in all food animals, with significant differences in antibiotic resistance and resistance genes. Additionally, differences in sequence types and plasmid genetics were observed in ESBL-EC from different animal sources.
FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY
(2022)
Article
Engineering, Environmental
Eri van Heijnsbergen, Gunnar Niebaum, Volker Laemmchen, Alicia Borneman, Lucia Hernandez Leal, Joerg Klasmeier, Heike Schmitt
Summary: This study investigated the occurrence of Escherichia coli and antibiotic-resistant E. coli in the Dutch-German transboundary catchment of the Vecht River. The study found a higher proportion of ESBL-EC in German wastewater treatment plants compared to Dutch plants. The modeling approach predicted E. coli concentrations to be below the threshold for good bathing water quality.
ENVIRONMENTAL SCIENCE & TECHNOLOGY
(2022)
Article
Agriculture, Dairy & Animal Science
Heba Badr, Reem M. Reda, Naglaa M. Hagag, Essam Kamel, Sara M. Elnomrosy, Amal I. Mansour, Momtaz A. Shahein, Samah F. Ali, Hala R. Ali
Summary: The study reveals the emergence of resistant bugs such as ESBL-E. coli in Egypt due to sub-therapeutic doses given to food chain animals. Infections caused by these superbugs are linked to high morbidity/mortality rates. The study suggests a potential zoonotic transmission between human and chicken isolates, emphasizing the importance of managing antibiotic use in veterinary field.
Article
Infectious Diseases
Mahmoud Fayez, Ahmed Elmoslemany, Ahmad A. Al Romaihi, Abdulfattah Y. Azzawi, Abdullah Almubarak, Ibrahim Elsohaby
Summary: Household cats in Saudi Arabia were found to be potential reservoirs of antimicrobial resistance (AMR), with a high frequency of multidrug resistant (MDR) and extended-spectrum beta-lactamases (ESBL) producing E. coli observed. Risk factors associated with MDR and ESBL-producing E. coli colonization in cats included previous antimicrobial treatment and the presence of a child in the cat's family. These findings raise concerns about the transmission of AMR from cats to humans and highlight the importance of a One Health approach.
Article
Infectious Diseases
Mohamed A. El-Mokhtar, Enas Daef, Aliae A. R. Mohamed Hussein, Maiada K. Hashem, Hebatallah M. Hassan
Summary: The study revealed a worrisome 15% colistin resistance rate in Escherichia coli strains isolated from patients with nosocomial pneumonia in a university hospital. These resistant strains carry various drug resistance and virulence-related genes, highlighting the importance of careful monitoring and infection control policies in the hospital setting.
Article
Environmental Sciences
Xiangpeng Zeng, Yu Cao, Lanning Wang, Min Wang, Qiang Wang, Qingxiang Yang
Summary: This study reveals that multidrug resistant (MDR) bacterial strains have a higher viability and different gene expression patterns compared to susceptible strains under hexavalent chromium (Cr(VI) stress. The MDR strain showed higher bacteriostatic rates and lower levels of reactive oxygen species compared to the susceptible strain. Moreover, the MDR strain also exhibited higher expression levels of antibiotic resistance genes and other related genes.
ENVIRONMENTAL POLLUTION
(2023)
Article
Biotechnology & Applied Microbiology
Muhammad Shafiq, Sadeeq Ur Rahman, Hazrat Bilal, Aftab Ullah, Sohail Muhammad Noman, Mi Zeng, Yumeng Yuan, Qingdong Xie, Xin Li, Xiaoyang Jiao
Summary: This study investigated the occurrence and molecular features of ESBL-producing and colistin-resistant E. coli isolates from healthy food-producing animals in Pakistan. The results showed a high proportion of ESBL and colistin resistance in the fecal samples, with most isolates exhibiting multidrug resistance. Various resistant determinants and mobile genetic elements were also found. These findings pose a significant threat to both animals and human communities.
JOURNAL OF APPLIED MICROBIOLOGY
(2022)
Article
Microbiology
Heba A. Ahmed, Ibrahim Elsohaby, Amina M. Elamin, Abeer E. Abd El-Ghafar, Gamilat A. Elsaid, Mervat Elbarbary, Rasha A. Mohsen, Tamer M. El Feky, Rasha M. El Bayomi
Summary: This study investigated the occurrence, pathotypes, virulotypes, genotypes, and antimicrobial resistance patterns of ESBL-producing E. coli in retail meat samples and workers in retail meat shops in Egypt. The results showed that the highest proportion of ESBL-producing E. coli isolates was found in duck meat and workers' hand swabs. Pathotyping revealed that the isolates belonged to groups A and B1. Virulotyping showed that the most prevalent virulence gene was Shiga toxin 2 (stx2) associated gene. Genotyping of the identified isolates from human and meat sources showed 100% similarity within the same cluster. All isolates were classified as MDR with an average MAR index of 0.7. AgNPs-H2O2 at various concentrations showed complete bacterial growth inhibition.
Article
Environmental Sciences
Christiane Schreiber, Nicole Zacharias, Sarah M. Essert, Felix Wasser, Heike Mueller, Esther Sib, Tabea Precht, Marijo Parcina, Gabriele Bierbaum, Ricarda M. Schmithausen, Thomas Kistemann, Martin Exner
Summary: The emergence of antibiotic-resistant clinically relevant facultative pathogenic bacteria in the environment has become a major global health challenge, with standardized methods for detection limited to clinical investigations. By proposing standardized cultivation methods, this study achieved effective detection of clinically-relevant antibiotic resistant bacteria in aquatic environmental samples, enhancing accuracy and efficiency in detection.
SCIENCE OF THE TOTAL ENVIRONMENT
(2021)
Review
Infectious Diseases
Janina Noster, Philipp Thelen, Axel Hamprecht
Summary: MDRE poses a global health threat and requires adjustments in healthcare management. Rapid detection of MDRE infections and colonization is key in guiding therapy and infection control.
Article
Microbiology
Georgi Merhi, Sara Amayri, Ibrahim Bitar, George F. Araj, Sima Tokajian
Summary: This study aimed to characterize multidrug resistant Enterobacter spp. and K. aerogenes isolates recovered from hospitalized patients in Lebanon. The isolates exhibited various resistance mechanisms and plasmid profiles. Multilocus sequence typing revealed the diversity within the isolates. Screening and continuous monitoring can effectively limit the dissemination of drug-resistant isolates in hospitalized patients.
MICROBIOLOGY SPECTRUM
(2023)
Article
Microbiology
Sien De Koster, Moniek Ringenier, Basil Britto Xavier, Christine Lammens, Dieter De Coninck, Katrien De Bruyne, Klaas Mensaert, Marjolein Kluytmans-van den Bergh, Jan Kluytmans, Jeroen Dewulf, Herman Goossens
Summary: This study characterized and traced ESBL-producing and ciprofloxacin-resistant Escherichia coli in Belgian food-producing animals. Multiple sequence types, resistance genes, and virulence profiles were detected. Transmission pathways within and between farms were identified, highlighting the importance of plasmid transmission in the spread of resistance.
FRONTIERS IN MICROBIOLOGY
(2023)
Article
Environmental Sciences
Rajasree Shanmuganathan, Davoodbasha MubarakAli, Desika Prabakar, Harshiny Muthukumar, Nooruddin Thajuddin, Smita S. Kumar, Arivalagan Pugazhendhi
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2018)
Article
Environmental Sciences
M. Narayanasamy, D. Dhanasekaran, G. Vinothini, N. Thajuddin
INTERNATIONAL JOURNAL OF ENVIRONMENTAL SCIENCE AND TECHNOLOGY
(2018)
Article
Immunology
Sekar Vijayakumar, Balasubramanian Malaikozhundan, Sathappan Shanthi, Baskaralingam Vaseeharan, Nooruddin Thajuddin
MICROBIAL PATHOGENESIS
(2017)
Article
Immunology
Felix LewisOscar, Chari Nithya, Sulaiman Ali Alharbi, Naiyf S. Alharbi, Nooruddin Thajuddin
MICROBIAL PATHOGENESIS
(2018)
Article
Immunology
Felix LewisOscar, Chari Nithya, Sulaiman Ali Alharbi, Naiyf S. Alharbi, Nooruddin Thajuddin
MICROBIAL PATHOGENESIS
(2018)
Article
Immunology
D. MubarakAli, F. LewisOscar, V. Gopinath, Naify S. Alharbi, Sulaiman Ali Alharbi, N. Thajuddin
MICROBIAL PATHOGENESIS
(2018)
Article
Green & Sustainable Science & Technology
Edachery Baldev, Davoodbasha Mubarakali, Kandasamy Saravanakumar, Chithirai Arutselvan, Naiyf S. Alharbi, Sulaiman Ali Alharbi, Velusamy Sivasubramanian, Nooruddin Thajuddin
Article
Microbiology
Syed Jahangir Hussain, Mohamed Murshid Nowshad, Nooruddin Thajuddin, Tamil Kumar Tamilarasan, Parveez Ahamed Abdul Azees
Summary: Five types of actinobacteria were isolated from acid corroded iron plates, with JMCACA3 strain selected for further study. This strain showed good growth with various carbon and nitrogen sources, and was identified as belonging to Streptomyces sp. The strain utilized and converted the corrosion inhibitor Benzimidazole as their energy source, highlighting the importance of developing more powerful corrosion inhibitors to combat actinobacterial influenced corrosion.
CURRENT MICROBIOLOGY
(2021)
Article
Dentistry, Oral Surgery & Medicine
Hoda S. Ismail, Parveez Ahamed Abdul Azees, Hanzhou Wang, Ashraf I. Ali, Rabab El Mehesen, Salah H. Mahmoud, Xiao-Dong Chen, Chih-Ko Yeh, Franklin Garcia-Godoy
Summary: This study compared the adhesion of periodontopathic bacteria to four restorative materials used for deep margin elevation. The findings showed that the tested flowable bulk fill exhibited better performance in terms of periodontopathic bacterial adhesion.
EUROPEAN JOURNAL OF ORAL SCIENCES
(2023)
Review
Dentistry, Oral Surgery & Medicine
Milos Marinkovic, Olivia N. Tran, Hanzhou Wang, Parveez Abdul-Azees, David D. Dean, Xiao-Dong Chen, Chih-Ko Yeh
Summary: Salivary gland dysfunction can cause severe oral and systemic diseases and compromise quality of life. Current treatments are palliative, but transplantation of allogeneic cells and the use of mesenchymal stem cells (MSCs) show promising potential for restoring saliva production. However, recent findings suggest that allogeneic MSCs may not be immune-privileged after transplantation, whereas autologous MSCs could be a viable solution. Advances in in vitro expansion of autologous MSCs on tissue-specific matrices offer a new therapeutic approach for restoring SG function.
INTERNATIONAL JOURNAL OF ORAL SCIENCE
(2023)
Article
Dentistry, Oral Surgery & Medicine
Bennett T. Amaechi, Parveez Ahamed AbdulAzees, Linda O. Okoye, Frederic Meyer, Joachim Enax
Article
Dentistry, Oral Surgery & Medicine
Bennett T. Amaechi, Parveez Ahamed AbdulAzees, Dina Ossama Alshareif, Marina Adel Shehata, Patricia Paula de Carvalho Sampaio Lima, Azadeh Abdollahi, Parisa Samadi Kalkhorani, Veronica Evans
Article
Dentistry, Oral Surgery & Medicine
Bennett T. Amaechi, Parveez Ahamed Abdul Azees, Suchitra Menon, Hariyali Kasundra
JOURNAL OF INVESTIGATIVE AND CLINICAL DENTISTRY
(2019)
Article
Biology
S. Dinesh Kumar, S. Ananth, P. Santhanam, A. Parveez Ahamed, N. Thajuddin
INDIAN JOURNAL OF EXPERIMENTAL BIOLOGY
(2019)
Article
Dentistry, Oral Surgery & Medicine
Bennett T. Amaechi, Hariyali Kasundra, Deepika Joshi, Azadeh Abdollahi, Parveez A. A. Azees, Linda O. Okoye
OPEN DENTISTRY JOURNAL
(2018)