Review
Plant Sciences
Luciene Ferreira de Lima, Jose Oreste de Oliveira, Joara Nalyda Pereira Carneiro, Cicera Norma Fernandes Lima, Henrique Douglas Melo Coutinho, Maria Flaviana Bezerra Morais-Braga
Summary: The Malvaceae family, particularly the Gossypium genus, has been traditionally used in folk medicine to treat microbial diseases. Literature review showed that various species within the Gossypium genus have demonstrated promising biological activities against protozoal, bacterial, fungal, and viral diseases.
JOURNAL OF ETHNOPHARMACOLOGY
(2021)
Review
Plant Sciences
Michella Dawra, Nancy Nehme, Youssef El Rayess, Marc El Beyrouthy, Patricia Taillandier, Jalloul Bouajila
Summary: This review summarizes the data on extracts and essential oils of unique plants in Lebanon, investigates their therapeutic actions, biological activities, and phytochemical composition. The study reveals the presence of various compounds in these plants, which are widely used in folk medicine and pharmacological applications.
SOUTH AFRICAN JOURNAL OF BOTANY
(2022)
Review
Food Science & Technology
Sneh Punia Bangar, Vandana Chaudhary, Nitya Sharma, Vasudha Bansal, Fatih Ozogul, Jose M. Lorenzo
Summary: This review provides a comprehensive collation of important information on the biosynthesis, mechanism of action, bioactivities, bioavailability, and toxicological potential of kaempferol. It highlights the antioxidant, antimicrobial, anticancer, neuroprotective, and hepatoprotective activity of kaempferol, while also mentioning the limitations of its poor water solubility and low bioavailability. The review suggests the utilization of advanced delivery systems to improve the stability and efficacy of kaempferol.
CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION
(2023)
Review
Biochemistry & Molecular Biology
Jimena Borgo, Laura C. Laurella, Florencia Martini, Cesar A. N. Catalan, Valeria P. Sulsen
Summary: The Stevia genus comprises a variety of plant species, with Stevia rebaudiana being the most important one. In addition to stevia, many other herbs in this genus are used for medicinal purposes, producing a variety of phytochemicals with pharmacological activities such as antioxidant, antiviral, and anti-inflammatory effects.
Article
Plant Sciences
Serisha Gangaram, Yougasphree Naidoo, Yaser Hassan Dewir, Salah El-Hendawy
Summary: Plant species belonging to the family Acanthaceae, particularly the genus Barleria, have significant medicinal potential and are widely used in traditional medicine and horticulture. These plants contain bioactive compounds that exhibit various pharmaceutical properties, such as antioxidant, anti-inflammatory, anticancer, and antidiabetic effects.
Review
Food Science & Technology
Changhong Li, Taotao Dai, Jun Chen, Mingshun Chen, Ruihong Liang, Chengmei Liu, Liqing Du, David Julian McClements
Summary: This review discusses the importance of structural modification of flavonoids to overcome their limitations and improve their applications, as well as the influence of modifications on biological activities, providing guidance for the synthesis of highly effective active agents.
CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION
(2022)
Article
Chemistry, Applied
Davlat Kh. Akramov, Gokhan Zengin, Sun Chul Kang, Komiljon Sh. Tojibaev, Mohamad Fawzi Mahomoodally, Shahnoz S. Azimova, Nilufar Z. Mamadalieva
Summary: Results of the study showed that the essential oils from Lagochilus species in Central Asia have varying chemical compositions, with L. inebrians essential oil exhibiting the best antioxidant and tyrosinase inhibitory activity, while L. setulosus essential oil demonstrated the strongest inhibitory effect against amylase.
NATURAL PRODUCT RESEARCH
(2021)
Review
Biochemistry & Molecular Biology
Qiang Wei, Qi-Zhao Li, Rui-Lin Wang
Summary: Taxus, also known as gold in plants, is a genus of the family Taxaceae, widely distributed around the world. The plants have significant importance in traditional Chinese medicine and have been used for various medicinal purposes. A comprehensive study was conducted to analyze the chemical structures, distribution, and bioactivity of flavonoids from Taxus plants. A total of 59 flavonoids with different skeletons were identified, exhibiting a wide range of biological activities. Further research and experiments are recommended for the development of drugs related to flavonoids.
Article
Plant Sciences
Jiahui Sun, Peipei Sun, Chuanzhi Kang, Lanyue Zhang, Lanping Guo, Yaping Kou
Summary: In recent years, essential oils have gained wide attention for their extensive applications in natural functional ingredients, pharmaceutical preparations, biomedical products, and the cosmetics industry. This study analyzed the chemical compositions and biological activities of essential oils extracted from six Lamiaceae herbs, showing their excellent and diverse biological activities that make them perfect natural functional ingredients in antioxidant, antitumor, or anti-arthritic drugs.
FRONTIERS IN PLANT SCIENCE
(2022)
Review
Plant Sciences
Naoual El Menyiy, Fatima-Ezzahrae Guaouguaou, Aicha El Baaboua, Nasreddine El Omari, Douae Taha, Najoua Salhi, Mohammad Ali Shariati, Tarik Aanniz, Taoufiq Benali, Gokhan Zengin, Mohamed El-Shazly, Imane Chamkhi, Abdelhakim Bouyahya
Summary: Centaurium erythraea is an important medicinal plant used in traditional medicine to treat various diseases. It exhibits diverse biological properties and contains several classes of secondary metabolites, confirming the link between traditional medicinal use and scientific experiments. Further investigation using in vivo pharmacological assays, toxicological tests, and pharmacokinetic studies are recommended to validate its traditional use.
JOURNAL OF ETHNOPHARMACOLOGY
(2021)
Article
Chemistry, Medicinal
Jirapak Ruttanapattanakul, Nitwara Wikan, Saranyapin Potikanond, Wutigri Nimlamool
Summary: Pinocembrin promotes proliferation and survival of keratinocytes by activating the MAPK and PI3K pathways. This research suggests that pinocembrin could be a potential wound closure-promoting agent.
Article
Plant Sciences
Andrew Magno Teixeira, Paulo Wender P. Gomes, Fabio Araujo da Silva, Paulo Weslem P. Gomes, Michael Murgu, Ricardo M. Borges
Summary: This study investigated Aristolochia trilabiata as a potential source of bioactive compounds. The medicinal uses of A. trilabiata were explored using the reverse ethnopharmacology method. It was found that the plant has anti-inflammatory properties and the methanolic extract exhibited potent antioxidant activity.
SOUTH AFRICAN JOURNAL OF BOTANY
(2023)
Review
Biochemistry & Molecular Biology
Karolina Lendzion, Agnieszka Gornowicz, Krzysztof Bielawski, Anna Bielawska
Summary: The genus Scorzonera consists of nearly 200 species naturally occurring in Europe, Asia, and northern parts of Africa, and has been used in folk medicine in Asia for centuries. Studies have identified various bioactive compounds in Scorzonera plants with antioxidant, anti-inflammatory, analgesic, and hepatoprotective properties, and potential activity against bacteria and fungi. Despite mild cytotoxicity against cancer cell lines, Scorzonera species show promise for wound healing therapy and treatment of microbial infections in medical products.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Article
Agricultural Engineering
Shaden A. M. Khalifa, Safaa M. Kotb, Shaden H. El-Seedi, Lutfun Nahar, Satyajit D. Sarker, Zhiming Guo, Xiaobo Zou, Syed G. Musharraf, Amir Reza Jassbi, Ming Du, Hesham R. El-Seedi
Summary: Since the 19th century, Boswellia sacra has been known for its economic and cultural values. It is cultivated in Oman and Yemen and used as a natural source of frankincense. Recent studies have shown that it has various biological activities, including anti-inflammatory, antimicrobial, and anti-cancer effects. Clinical trials have also demonstrated its effectiveness against certain diseases. Further research is needed to explore its potential and protect the trees from extinction.
INDUSTRIAL CROPS AND PRODUCTS
(2023)
Review
Chemistry, Medicinal
Karen Y. Reyes-Melo, Adrian A. Galvan-Rodrigo, Isai E. Martinez-Olivo, Guillermo Nunez-Mojica, Francisco G. Avalos-Alanis, Abraham Garcia, Maria del Rayo Camacho-Corona
Summary: Larrea tridentata is a dominant shrub in North American deserts known for its traditional uses and diverse chemical composition. Besides the well-studied NDGA, other metabolites such as 3'-demethoxy-6-O-demethylisoguaiacin contribute to various biological activities of the plant.
CURRENT TOPICS IN MEDICINAL CHEMISTRY
(2021)
Article
Biochemistry & Molecular Biology
Victor de Carvalho Martins, Liliana Princisval Franca, Yasmim da Silva Ferreira, Daniele Cabral Pires, Barbara de Souza Cardoso, Manuela Cristina Pessanha de Araujo Santiago, Sidney Pacheco, Marcelo da Costa Souza, Cristiano Jorge Riger, Ronoel Luiz de Oliveira Godoy, Mario Geraldo de Carvalho
Summary: Eugenia copacabanensis and Myrciaria tenella leaves were analyzed for their chemical compounds, showing potential antioxidant protection with a high diversity of phenolic compounds, especially impacting glutathione-deficient cells.
CHEMISTRY & BIODIVERSITY
(2021)
Article
Chemistry, Applied
Gabriela Mastrangelo Goncalves, Victor de Carvalho Martins, Andre Romero Henrique da Costa, Thayane Ferreira da Costa Fernandes, Sidney Pacheco, Paola Ervatti Gama, Marcelo da Costa Souza, Ronoel Luiz de Oliveira Godoy, Roberto Laureano-Melo, Wellington da Silva Cortes, Mario Geraldo de Carvalho, Bruno Guimaraes Marinho
Summary: The study characterized the essential oil of Myrciaria tenella leaves and evaluated its effects on acute pain and inflammation, finding that the oil mainly consists of hydrocarbon terpenes. Results showed that the oil had significant anti-inflammatory and analgesic effects.
JOURNAL OF ESSENTIAL OIL RESEARCH
(2021)
Article
Chemistry, Applied
Victor de Carvalho Martins, Manuela Cristina Pessanha de Araujo Santiago, Sidney Pacheco, Renata Galhardo Borguini, Marcelo da Costa Souza, Mario Geraldo de Carvalho, Ronoel Luiz de Oliveira Godoy
Summary: This study for the first time revealed the chemical composition of Myrcia eriopus fruit, showing high levels of anthocyanins and antioxidant potential. It demonstrates the fruit's potential as a new source of bioactive anthocyanins.
NATURAL PRODUCT RESEARCH
(2022)
Article
Biochemistry & Molecular Biology
Matheus Andrade Rocha Costa, Simone Andrade Gualberto, Polyany Cabral Oliveira, Iasnaia Maria de Carvalho Tavares, Nivio Batista Santana, Danilo Junqueira Leao, Debora Cardoso da Silva, Dhiessica Dos Santos Ribeiro, Neura Mendes da Silva, Pedro Henrique Santos, Mario Geraldo de Carvalho, Marcelo Franco
Summary: This study evaluated enzymatic pretreatment and hydrodistillation to increase the extraction efficiency of essential oil from Croton argyrophyllus leaves. The results showed that enzymatic pretreatment increased essential oil yield by 9.35% for fresh leaves and 6.77% for dry leaves under optimal experimental conditions. This approach holds promise for obtaining essential oil for therapeutic purposes without altering its composition.
BIOTECHNOLOGY AND APPLIED BIOCHEMISTRY
(2022)
Article
Entomology
Gracieli Gomes Nonato Bressanin, Caio Marcio de Oliveira Monteiro, Paula Marchesini, Tatiane Pinheiro Lopes Novato, Francisco Eduardo Aragao Catunda Junior, Sabrina Rita Da Fonseca Rezende, Emerson Guedes Pontes, Mario Geraldo de Carvalho, Andreia Lima Tome Melo, Wendell Marcelo de Souza Perinotto
Summary: The study found that the essential oil from Curcuma zedoaria exhibited good acaricidal activity against Rhipicephalus microplus, while the oil from Alpinia zerumbet had a lesser effect. The major components in Curcuma zedoaria oil, such as 1,8-cineole, curzerenone and camphor, may contribute to its efficacy.
INTERNATIONAL JOURNAL OF ACAROLOGY
(2022)
Article
Endocrinology & Metabolism
Tassiana Cristina Talpo, Bruno Pereira Motta, Juliana Oriel de Oliveira, Ingrid Delbone Figueiredo, Camila Graca Pinheiro, Carlos Henrique Correa dos Santos, Mario Geraldo de Carvalho, Iguatemy Lourenco Brunetti, Amanda Martins Baviera
Summary: The study showed that Siolmatra brasiliensis extract has antiobesogenic effects, improves insulin sensitivity and glucose tolerance, reduces total cholesterol levels, decreases levels of glycoxidative stress biomarkers, and improves endogenous antioxidant defenses.
OBESITY RESEARCH & CLINICAL PRACTICE
(2022)
Article
Chemistry, Medicinal
Rafaela Oliveira Ferreira, Jessica Colodette Galo, Paula Monteiro Lopes, Daniela Sales Alviano Moreno, Tania Maria Sarmento da Silva, Mario Geraldo de Carvalho
Summary: This study isolated and identified bioactive compounds from Clusia nemorosa fruits and investigated their antimicrobial and antioxidant activities. The compounds, except for one, were described for the first time in this species, and showed potential in the treatment of diseases related to oxidative stress.
NATURAL PRODUCTS JOURNAL
(2022)
Article
Plant Sciences
Gisely de Lima Oliveira, Helena Regina Pinto Lima, Bruno Couto da Silva, Mario Geraldo de Carvalho, Rosane Nora de Castro, Heber dos Santos Abreu, Alexandre Monteiro de Carvalho
Summary: This study characterized the lignin in the cell wall of Euterpe oleracea Mart., finding that the stem samples had high lignin content, which decreased after treatment with NaOH. Spectroscopic and chromatographic analysis revealed the composition and structural units of GS-type lignin.
Article
Food Science & Technology
Jonathas de Souza Vieira, Vanessa Sales de Oliveira, Mara Junqueira Carneiro, Tatiana Labre da Silva, Ivanilda Maria Augusta, Mario Geraldo de Carvalho, Alexandra Christine Helena Frankland Sawaya, Tatiana Saldanha
Summary: This review comprehensively describes the phenolic compounds in pink pepper, mainly phenolic acids and flavonoids. The rich phenolic composition contributes to the extensively reported antioxidant capacity of pink pepper. The application of pink pepper fruit as a natural antioxidant has been investigated through extracts, direct addition, and the use of residues, showing promising results in reducing harmful compounds and lipid oxidation in various food matrices. Pink pepper is highlighted as an alternative to synthetic antioxidants in processed food.
Article
Biochemistry & Molecular Biology
Frances Regiane dos Santos, Sabrina Rita da Fonseca Rezende, Luan Valim dos Santos, Elaine R. M. Nery da Silva, Matheus Silva Caiado, Marco Andre Alves de Souza, Emerson Guedes Pontes, Mario Geraldo de Carvalho, Raimundo Braz Filho, Rosane Nora Castro
Summary: This study aimed to extract and characterize essential oils from Myrtaceae species and evaluate their larvicidal and fungicidal effects. The results showed that the composition and biological activities of the essential oils varied among different species.
CHEMISTRY & BIODIVERSITY
(2023)
Article
Agronomy
Thaisa de Oliveira Silveira, Mayara de Mello Marques, Gustavo Torres dos Santos Amorim, Mario Geraldo de Carvalho, Pedro Correa Damasceno
Summary: This study characterized and classified a germplasm collection of bitter melon to assess its genetic diversity and identify genotypes of agronomic interest. The study found that the genotypes could be grouped into different clusters, with variations in fruit and seed production as well as sizes. The population showed high diversity, with higher intra-group diversity among small fruit genotypes.
Article
Agronomy
Edson Cardoso Teixeira, Almir Ribeiro de Carvalho Jr, Mario Geraldo de Carvalho, Sonia Pereira Cabrera, Tania Maria Sarmento da Silva, Rafaela Oliveira Ferreira
Summary: Leaves of Caryocar brasiliense are used in folk medicine to treat respiratory diseases. An analysis of the leaves revealed high levels of phenols and flavonoids, as well as antioxidant activity. The use of ultra-high-performance liquid chromatography and mass spectrometry allowed for the identification of several compounds, with 21 being discovered for the first time in C. brasiliense. These findings suggest that C. brasiliense may serve as a potential source of bioactive substances with antioxidant properties.
EMIRATES JOURNAL OF FOOD AND AGRICULTURE
(2022)
Article
Chemistry, Multidisciplinary
Mario Geraldo de Carvalho, Fernanda Cristina M. Rondon, Daniela Santos Carneiro-Torres, Patricia Fampa, Claudia Maria L. Bevilaqua, Paulo Nogueira Bandeira, Geovany Amorim Gomes
Summary: This study chemically characterized and tested the anti-Leishmania infantum activity of essential oils from two plant species. The results showed that these oils have potential as leishmanicidal agents.
REVISTA VIRTUAL DE QUIMICA
(2022)
Article
Multidisciplinary Sciences
Debora R. De Oliveira, Mariana R. Da Silva, Otavio A. Chaves, Rosane N. Castro, Marcia C. C. De Oliveira, Raimundo Braz-Filho, Mario G. De Carvalho
Summary: Phytochemical studies on Cespedesia spathulata leaves identified new metabolites and assessed their modulating effects on tyrosinase enzyme. The results showed that certain compounds and fractions exhibited inhibition, while others showed activation of the enzyme's activity.
ANAIS DA ACADEMIA BRASILEIRA DE CIENCIAS
(2021)
Article
Parasitology
Paula Marchesini, Debora Ramos de Oliveira, Geovany Amorim Gomes, Tigressa Helena Soares Rodrigues, Ralph Maturano, Queli Cristina Fidelis, Francisco Eduardo Aragao Catunda Junior, Mario Geraldo de Carvalho, Vania Rita Elias Pinheiro Bittencourt, Caio Marcio Oliveira Monteiro
Summary: The essential oils and their major compounds showed high acaricidal activity against Rhipicephalus microplus, particularly (E)-cinnamaldehyde and alpha-bisabolol demonstrated significant mortality rates in the tests.
REVISTA BRASILEIRA DE PARASITOLOGIA VETERINARIA
(2021)
