MiniCD4 protein resistance mutations affect binding to the HIV-1 gp120 CD4 binding site and decrease entry efficiency

Mechanism of Neutralization by the Broadly Neutralizing HIV-1 Monoclonal Antibody VRC01

(2011) Y. Li et al.   JOURNAL OF VIROLOGY

Sequence and Structural Convergence of Broad and Potent HIV Antibodies That Mimic CD4 Binding

(2011) J. F. Scheid et al.   SCIENCE

In VivoPatterns of Resistance to the HIV Attachment Inhibitor BMS-488043

(2010) Nannan Zhou et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

CD4 mimics targeting the HIV entry mechanism and their hybrid molecules with a CXCR4 antagonist

(2010) Tetsuo Narumi et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Human anti–HIV-neutralizing antibodies frequently target a conserved epitope essential for viral fitness

(2010) John Pietzsch et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Enhanced Exposure of Human Immunodeficiency Virus Type 1 Primary Isolate Neutralization Epitopes through Binding of CD4 Mimetic Compounds

(2010) K. Yoshimura et al.   JOURNAL OF VIROLOGY

Analysis of Memory B Cell Responses and Isolation of Novel Monoclonal Antibodies with Neutralizing Breadth from HIV-1-Infected Individuals

(2010) Davide Corti et al.   PLoS One

Crystal Structure of the Neutralizing Llama VHH D7 and Its Mode of HIV-1 gp120 Interaction

(2010) Andreas Hinz et al.   PLoS One

Rational Design of Envelope Identifies Broadly Neutralizing Human Monoclonal Antibodies to HIV-1

(2010) X. Wu et al.   SCIENCE

Mechanism of Human Immunodeficiency Virus Type 1 Resistance to Monoclonal Antibody b12 That Effectively Targets the Site of CD4 Attachment

(2009) X. Wu et al.   JOURNAL OF VIROLOGY

Broad and Potent Neutralizing Antibodies from an African Donor Reveal a New HIV-1 Vaccine Target

(2009) L. M. Walker et al.   SCIENCE

Soluble CD4 and CD4-Mimetic Compounds Inhibit HIV-1 Infection by Induction of a Short-Lived Activated State

(2009) Hillel Haim et al.   PLoS Pathogens

CD4 mimetic miniproteins: potent anti-HIV compounds with promising activity as microbicides

(2008) Y. Van Herrewege et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Combinatorial Optimization of a CD4-Mimetic Miniprotein and Cocrystal Structures with HIV-1 gp120 Envelope Glycoprotein

(2008) François Stricher et al.   JOURNAL OF MOLECULAR BIOLOGY

Llama Antibody Fragments with Cross-Subtype Human Immunodeficiency Virus Type 1 (HIV-1)-Neutralizing Properties and High Affinity for HIV-1 gp120

(2008) A. Forsman et al.   JOURNAL OF VIROLOGY

An Alteration of Human Immunodeficiency Virus gp41 Leads to Reduced CCR5 Dependence and CD4 Independence

(2008) B. M. Taylor et al.   JOURNAL OF VIROLOGY

Small-Molecule CD4 Mimics Interact with a Highly Conserved Pocket on HIV-1 gp120

(2008) Navid Madani et al.   STRUCTURE

A simple one-step method for the preparation of HIV-1 envelope glycoprotein immunogens based on a CD4 mimic peptide

(2008) Grégoire Martin et al.   VIROLOGY