Article
Health Care Sciences & Services
Xiao-Su Hu, Katherine Beard, Mary Catherine Sherbel, Thiago D. Nascimento, Sean Petty, Eddie Pantzlaff, David Schwitzer, Niko Kaciroti, Eric Maslowski, Lawrence M. Ashman, Stephen E. Feinberg, Alexandre F. DaSilva
Summary: The study examines the cortical analgesic processes between traditional mindful breathing and virtual reality breathing. Both interventions increased pain thresholds, but had opposite brain mechanisms, with mindful breathing emphasizing interoception and virtual reality breathing emphasizing exteroception. This suggests distinct modulations in the processing of noxious inputs.
JOURNAL OF MEDICAL INTERNET RESEARCH
(2021)
Review
Biochemistry & Molecular Biology
Charlotte Delrue, Sander De Bruyne, Marijn M. Speeckaert
Summary: Traditional renal biomarkers are insensitive for early detection of kidney disease. Infrared spectroscopy offers a label-free and non-destructive method for quick and inexpensive diagnosis of kidney disorders. This review provides an overview of the applications of near- and mid-infrared spectroscopy in patients with acute kidney injury and chronic kidney disease.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Medicine, General & Internal
Martijn van Hooff, Jem Arnold, Eduard Meijer, Paul Schreuder, Marta Regis, Lin Xu, Marc Scheltinga, Hans Savelberg, Goof Schep
Summary: This study compared the diagnostic accuracy of NIRS-derived variables with ABI(Flexed) in diagnosing FLIA. The results showed that NIRS kinetic variables combined with ABI(Flexed) had a higher diagnostic accuracy, while ABI(Flexed) alone had worse test characteristics.
JOURNAL OF CLINICAL MEDICINE
(2022)
Review
Chemistry, Multidisciplinary
Giovanni Pizzi, Silvia Milana, Andrea C. Ferrari, Nicola Marzari, Marco Gibertini
Summary: This study focuses on the Raman and infrared spectroscopy of layered materials, presenting a general approach to predict spectroscopic fan diagrams for multilayers composed of identical layers. The method combines a description of normal modes with symmetry arguments to identify optically active modes and provide diagrams for any stack of identical layers.
Article
Physiology
Siana Jones, Therese Tillin, Suzanne Williams, Alicja Rapala, Nishi Chaturvedi, Alun D. Hughes
Summary: Measuring local haemodynamics in skeletal muscle can provide valuable insights into tissue oxygen delivery during high demand situations such as exercise. This study compared the skeletal muscle microvascular response during post-occlusive reactive hyperaemia (PORH) with the response to exercise using near-infrared spectroscopy (NIRS) and examined the associations between muscle measures and exercise capacity or sex. The results showed that these local microvascular NIRS measures are associated with exercise capacity in older adults and can detect differences in microvascular reactivity between men and women in a community-based sample.
FRONTIERS IN PHYSIOLOGY
(2022)
Article
Nutrition & Dietetics
Chuan Zhang, Christopher M. Modlesky, Kevin K. McCully
Summary: The study evaluated the utility and reliability of near-infrared spectroscopy (NIRS) in measuring tibial hemodynamics and metabolic rate. The results showed that NIRS is a suitable tool for monitoring hemodynamics and metabolism in the tibia. Additionally, the local muscle exercise protocol utilized did not influence bone hemodynamics or metabolic rate, suggesting that high level of loading and exercise volume may be needed to elicit measurable metabolic changes in bone.
APPLIED PHYSIOLOGY NUTRITION AND METABOLISM
(2021)
Article
Chemistry, Applied
Arian Amirvaresi, Nastaran Nikounezhad, Maryam Amirahmadi, Bahram Daraei, Hadi Parastar
Summary: The study found that NIR spectroscopy is more effective than MIR in predicting the origin of saffron samples, while PLS-DA shows high accuracy in detecting adulterants, with NIR demonstrating excellent performance in estimating the level of adulteration.
Article
Environmental Sciences
Felipe Contreras-Briceno, Maximiliano Espinosa-Ramirez, Eduardo Moya-Gallardo, Rodrigo Fuentes-Kloss, Luigi Gabrielli, Oscar F. Araneda, Gines Viscor
Summary: The study found that deoxygenation of m.intercostales during incremental exercise in high-level competitive marathon runners is directly associated with aerobic capacity and increased lung ventilation and respiratory rate, but not tidal volume. Furthermore, m.intercostales shows less deoxygenation than m.vastus laterallis at intensities above the aerobic ventilatory threshold.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH
(2021)
Article
Physiology
Norita Gildea, Adam McDermott, Joel Rocha, Domenico Crognale, Aaron Nevin, Donal O'Shea, Simon Green, Mikel Egana
Summary: This study assessed the rates of adjustment in oxygen uptake and muscle deoxygenation during high-intensity cycling in type 2 diabetes patients. The results showed that low-volume high-intensity interval training and moderate-intensity continuous training both resulted in similar improvements in oxygen uptake kinetics without changes in muscle deoxygenation kinetics.
JOURNAL OF APPLIED PHYSIOLOGY
(2022)
Article
Chemistry, Analytical
Mika Ishigaki, Atsushi Ito, Risa Hara, Shun-ichi Miyazaki, Kodai Murayama, Keisuke Yoshikiyo, Tatsuyuki Yamamoto, Yukihiro Ozaki
Summary: This study successfully developed a method of monitoring the increasing number of amide bonds with the elongation of peptide chain length using NIR spectroscopy. By evaluating the dehydration occurring between amino acids and constructing a calibration model with a high determination coefficient, the study provided valuable insights for analyzing amide bonds in the NIR spectra of proteins, polyamino acids, polypeptides, and polyamides.
ANALYTICAL CHEMISTRY
(2021)
Article
Respiratory System
Jefta van Dijk, Alette A. Koopman, Limme B. de Langen, Sandra Dijkstra, Johannes G. M. Burgerhof, Robert G. T. Blokpoel, Martin C. J. Kneyber
Summary: In this study, we investigated the impact of different modes on patient effort during pediatric ventilator liberation and studied whether reducing pressure support would increase patient effort. The results showed that patient effort did not increase in the continuous spontaneous ventilation mode, and reducing pressure support did not lead to clinically relevant increases in patient effort.
RESPIRATORY RESEARCH
(2022)
Article
Biology
Felipe Contreras-Briceno, Maximiliano Espinosa-Ramirez, Vicente Keim-Bagnara, Matias Carreno-Roman, Rafael Rodriguez-Villagra, Fernanda Villegas-Belmar, Gines Viscor, Luigi Gabrielli, Marcelo E. Andia, Oscar F. Araneda, Daniel E. Hurtado
Summary: The study aimed to evaluate if changes in oxygen saturation levels at intercostal muscles using NIRS could determine RCP during exercise in triathletes. The results showed a good agreement between NIRS and visual methods in determining RCP, indicating that changes in SmO2 m.intercostales measured by NIRS can effectively determine RCP in triathletes.
Article
Pediatrics
Rutger C. C. Flink, Christopher J. L. Newth, Justin C. C. Hotz, Martin C. J. Kneyber, Patrick A. A. Ross, Frans H. H. de Jongh, Anton. H. van Kaam, Robinder G. G. Khemani
Summary: Effort of Breathing (EOB) calculations using esophageal manometry and Respiratory Inductance Plethysmography (RIP) showed a strong correlation with Work of Breathing (WOB) measurements based on spirometry. This suggests that RIP can be a reliable alternative to spirometry for measuring respiratory workload in nonhuman primates.
PEDIATRIC RESEARCH
(2023)
Article
Agriculture, Multidisciplinary
Cristina Cecchini, Francesca Antonucci, Corrado Costa, Alessandra Marti, Paolo Menesatti
Summary: This study utilized near-infrared spectroscopy to evaluate the quality of durum wheat semolina, finding that protein content correlated best with spectral data and GlutoPeak indices also exhibited good correlation with spectral data. Better modeling efficiency was obtained using the low-cost swNIR technology.
JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE
(2021)
Article
Biotechnology & Applied Microbiology
Yoo Hwan Kim, Seung-Ho Paik, Youngmin Kim, Jaechul Yoon, Yong Suk Cho, Dohern Kym, Jun Hur, Wook Chun, Beop-Min Kim, Byung-Jo Kim
Summary: This study assessed the burn extent and depth in patients with burns using a custom-built 36-channel functional near-infrared spectroscopy system. Hemodynamic tissue signals measured during fNIRS showed significant differences between different burn categories, indicating that functional near-infrared spectroscopy can help with the early judgment of burn extent and depth by reflecting differences in the oxygen saturation levels in the skin.
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
(2023)
Article
Physiology
Reid A. Mitchell, Scott T. Apperley, Satvir S. Dhillon, Julia Zhang, Kyle G. Boyle, Andrew H. Ramsook, Michele R. Schaeffer, Kathryn M. Milne, Yannick Molgat-Seon, A. William Sheel, Jordan A. Guenette
Summary: This case report describes a 59-year-old female 4 years post-left-sided extrapleural pneumonectomy who underwent incremental cycling testing and inspiratory muscle training (IMT) for 12 weeks. Results showed that IMT effectively increased respiratory muscle strength.
JOURNAL OF APPLIED PHYSIOLOGY
(2021)
Article
Physiology
Sarah A. Angus, William R. Henderson, Mohammad M. Banoei, Yannick Molgat-Seon, Carli M. Peters, Hanna R. Parmar, Donald E. G. Griesdale, Mypinder Sekhon, Andrew William Sheel, Brent W. Winston, Paolo B. Dominelli
Summary: Therapeutic hypothermia can reduce injury and inflammation associated with experimentally induced short-term ARDS. Gas exchange was not affected. The hypothermic injured group showed a reduction in pro-inflammatory metabolites, an increase in anti-inflammatory metabolites, and a reduction in inflammatory cytokines compared to the normothermic injured group.
PHYSIOLOGICAL REPORTS
(2022)
Article
Neurosciences
Cameron M. Gee, Alexandra M. Williams, Carli M. Peters, Neil D. Eves, Andrew W. Sheel, Christopher R. West
Summary: Cervical spinal cord injury negatively affects cardiac and respiratory function, particularly with greater expiratory positive pressure. Inspiratory loading does not significantly improve left ventricular function in cervical spinal cord injury patients, and neither inspiratory nor expiratory loading affects cardiac function or lung volumes in healthy participants.
JOURNAL OF PHYSIOLOGY-LONDON
(2022)
Article
Nutrition & Dietetics
Shalaya Kipp, Michael G. Leahy, Jacob A. Hanna, A. William Sheel
Summary: Dyspnea and leg discomfort during exercise can be influenced by expectations, while perceived exertion (RPE) remains unchanged. The effect of expectations must be considered when interpreting sensations of breathlessness.
APPLIED PHYSIOLOGY NUTRITION AND METABOLISM
(2022)
Article
Critical Care Medicine
Carleen Batson, Logan Froese, Mypinder Sekhon, Donald Griesdale, Alwyn Gomez, Eric P. Thelin, Rahul Raj, Marcel Aries, Clare Gallagher, Francis Bernard, Andreas H. Kramer, Frederick A. Zeiler
Summary: This study investigates the impact of age and biological sex on cerebral physiology and finds a positive linear correlation between PAx, RAC, and age, but no relationship between PRx and age.
JOURNAL OF NEUROTRAUMA
(2023)
Article
Physiology
Emily A. M. Gerson, Paolo B. Dominelli, Michael G. Leahy, Shalaya Kipp, Jordan A. Guenette, Bruno Archiza, Andrew William Sheel
Summary: Ventilatory assist during exercise can reduce the work and electrical activity of the diaphragm, which is important for exercise training studies aiming to reduce diaphragm work in patients with cardiopulmonary disease.
EXPERIMENTAL PHYSIOLOGY
(2023)
Article
Neurosciences
Brooke M. Shafer, Massimo Nardone, Anthony V. Incognito, Tyler D. Vermeulen, Andre L. Teixeira, Philip J. Millar, A. William Sheel, Chris West, Najib Ayas, Glen E. Foster
Summary: Post-hypoxia sympathoexcitation reduces vascular tone and diminishes sympathetic signalling. Blunted sympathetic transduction during acute hypoxia is confirmed, and the effects of hypoxia on the relationship between mean arterial pressure (MAP) and action potential (AP) activity are examined. It is found that MAP changes are blunted during acute hypoxia but restored in recovery, and asynchronous APs elicit smaller MAP changes compared to synchronous APs.
JOURNAL OF PHYSIOLOGY-LONDON
(2023)
Article
Neurosciences
Michael G. G. Leahy, Shalaya Kipp, Jenna M. M. Benbaruj, Nisha Charkoudian, Glen E. E. Foster, Michael S. S. Koehle, A. William Sheel
Summary: The effects of ageing and female sex hormones on the respiratory muscle metaboreflex are unclear. Our study found that older adults have a heightened pressor response to inspiratory work, and there is no difference in this response between older males and post-menopause females.
JOURNAL OF PHYSIOLOGY-LONDON
(2023)
Article
Physiology
Andrew H. H. Ramsook, Michele R. R. Schaeffer, Reid A. A. Mitchell, Satvir S. S. Dhillon, Kathryn M. M. Milne, Olivia N. N. Ferguson, Joseph H. H. Puyat, Michael S. S. Koehle, A. William Sheel, Jordan A. A. Guenette
Summary: The impact of neural mechanisms on diaphragm fatigability following inspiratory pressure threshold loading (IPTL) was investigated in males and females. The study found that while there were differences in diaphragm fatigability between males and females after training, there was no significant difference in diaphragm fatigability between the sexes. The results suggest that neural mechanisms contribute to diaphragm fatigability and this contribution is similar between males and females following IPTL.
PHYSIOLOGICAL REPORTS
(2023)
Article
Physiology
Paige A. Reinhard, Bruno Archiza, Joseph F. Welch, Jenna Benbaruj, Jordan A. Guenette, Michael S. Koehle, A. William Sheel
Summary: In this study, it was found that healthy males and females developed similar levels of diaphragm fatigue following cycling exercise at the same relative intensity, despite females having longer cycling time. Additionally, females showed slower recovery from diaphragm fatigue in hypoxia compared to males.
PHYSIOLOGICAL REPORTS
(2023)
Article
Medicine, General & Internal
Eleen Yang, Mypinder Sekhon, Donald Griesdale
Summary: This case report describes a previously healthy early adolescent female who developed severe neurological deterioration due to meningococcal meningitis. Monitoring of intracranial pressure and brain tissue oxygen revealed a complete absence of autoregulation in the patient, emphasizing the importance of maintaining adequate cerebral oxygenation while avoiding increased intracranial pressure. Despite initial complications, the patient made a full neurologic recovery.
Article
Nutrition & Dietetics
Yannick Molgat-Seon, Mathieu A. T. Sawatzky, Paolo B. Dominelli, Miranda Kirby, Jordan A. Guenette, Jean Bourbeau, Wan C. Tan, A. William Sheel
Summary: In healthy adults, females have a lower airway-to-lung ratio and experience higher exertional dyspnoea compared to males. However, the study findings suggest that sex differences in airway size do not contribute significantly to the differences in exertional dyspnoea between males and females.
APPLIED PHYSIOLOGY NUTRITION AND METABOLISM
(2023)
Article
Neurosciences
Sarah A. Angus, Joshua L. Taylor, Leah M. Mann, Alexandra M. Williams, Eric J. Stoehr, Jason S. Au, Andrew William Sheel, Paolo B. Dominelli
Summary: This study aimed to investigate the effect of respiration on cardiac output during semi-supine cycle exercise. The results showed that attenuating intrathoracic pressure swings can reduce left ventricular preload and ejection.
JOURNAL OF PHYSIOLOGY-LONDON
(2023)
Meeting Abstract
Sport Sciences
Shalaya Kipp, Michael Leahy, Jacob Hanna, A. William Sheel
MEDICINE & SCIENCE IN SPORTS & EXERCISE
(2022)
Article
Physiology
Carli M. Peters, Yannick Molgat-Seon, Paolo B. Dominelli, Anthony M. D. Lee, Pierre Lane, Stephen Lam, Andrew W. Sheel
Summary: This study investigated the impact of airway luminal area (Ai) on respiratory mechanics during dynamic exercise. It found that individuals with smaller Ai experienced higher resistive work of breathing, indicating a correlation between airway size and breathing efficiency during exercise. These findings lay the foundation for further research on the relationship between airway size and respiratory mechanics during physical activity.
PHYSIOLOGICAL REPORTS
(2021)
Article
Physiology
Alyssa R. Mickle, Jesus D. Penaloza-Aponte, Richard Coffey, Natale A. Hall, David Baekey, Erica A. Dale
Summary: Closed-loop epidural stimulation (CL-ES) can improve respiratory deficits caused by cervical spinal cord injury, restoring diaphragm activity and enhancing contralateral activity. This treatment has the potential to lead to lasting recovery and device independence.
RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY
(2024)
Article
Physiology
Shawn Miller Jr, Edgar Juarez Lopez, Jessica M. L. Grittner, Brendan J. Dougherty
Summary: This study tested the impact of CO2 supplementation at different concentrations on ventilatory long-term facilitation (vLTF) in rats and found that 2% CO2 supplementation during and after acute, intermittent hypoxia (AIH) was sufficient to maintain isocapnia and induce significant vLTF.
RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY
(2024)
Article
Physiology
Behnam Vafadari, Yoshitaka Oku, Charlotte Tacke, Ali Harb, Swen Huelsmann
Summary: The preBo·tzinger Complex (preBo·tC) in the brainstem plays a critical role in generating respiratory rhythm. This study aimed to investigate the activity of inhibitory glycinergic neurons in the preBo·tC of anesthetized mice. Using juxtacellular recordings and optogenetic activation, the researchers were able to identify and characterize the activity pattern of these inhibitory neurons in relation to the breathing rhythm.
RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY
(2024)
Article
Physiology
Stephen M. Johnson, Maia G. Gumnit, Sarah M. Johnson, Tracy L. Baker, Jyoti J. Watters
Summary: Low-level activation of mu-opioid receptors can increase the amplitude of inspiratory bursts in neonatal rat brainstem-spinal cord preparations. Endomorphin-2, an endogenous ligand for these receptors, was found to have similar effects. Disinhibition of inhibitory synaptic transmission may not be involved in the changes induced by endomorphin-2, and different mechanisms may underlie the increase in burst amplitude and decrease in burst frequency.
RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY
(2024)
Article
Physiology
Raphael Martins de Abreu, Beatrice Cairo, Patricia Rehder-Santos, Claudio Donisete da Silva, Etore De Favari Signini, Juliana Cristina Milan-Mattos, Camila Akemi Sakaguchi, Aparecida Maria Catai, Alberto Porta
Summary: The purpose of this study was to determine the association between exercise capacity based on peak oxygen uptake (VO2peak) and resting cardiorespiratory coupling (CRC) levels. The results showed that resting CRC values were associated with exercise capacity in athletes but not in non-athletes.
RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY
(2024)
Article
Physiology
Sarah M. Russel, Raluca E. Gosman, Katherine Gonzalez, Joshua Wright, Dennis O. Frank-Ito
Summary: This study aimed to characterize the response of different nasal morphologies to airflow-related variables during rapid/deep inspiration. The results showed that notched nasal vestibules had higher resistance values and airflow velocities, while standard nasal vestibules had higher mucosal heat flux. Different nasal phenotypes may predispose individuals to exercise-induced rhinitis.
RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY
(2024)
Article
Physiology
Ivan Poliacek, Lukas Martvon, Michal Simera, Marcel Veternik, Jakub Misek, Lucia Cibulkova, Kimberly E. Iceman, Donald C. Bolser, Teresa Pitts
Summary: An animal model study evaluated the effects of an abdominal incision on cough and swallow, revealing that abdominal wall manipulations can increase pharyngeal muscle activity during swallow without affecting the cough reflex. Swallowing tended to occur more during the inspiratory phase. The results highlight the important role of abdominal wall sensory feedback in regulating swallow motor patterns.
RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY
(2024)
Article
Physiology
Rui Yu, Tatsuma Okazaki, Yuzhuo Ren, Junko Okuyama, Satoru Ebihara, Shin-Ichi Izumi
Summary: Body postures significantly influence respiratory muscle force, cough pressure, subjective ease of coughing, and pulmonary function. The 60-degree semi-recumbent posture and sitting posture show better results compared to the supine posture.
RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY
(2024)
Article
Physiology
Suzuna Sato, Koji Ishida, Noriko I. Tanaka, Keisho Katayama
Summary: Respiratory muscle endurance training has beneficial effects on whole-body endurance performance. A novel high-intensity interval (HII) protocol is found to enhance the efficacy of respiratory muscle training programs.
RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY
(2024)
Letter
Physiology
R. Arieli
RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY
(2024)
Correction
Physiology
Ivan Poliacek, Michal Simera, Marcel Veternik, Zuzana Kotmanova, Teresa Pitts, Jan Hanacek, Jana Plevkova, Peter Machac, Nadezda Visnovcova, Jakub Misek, Jan Jakus
RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY
(2024)
Article
Physiology
Dimitrios I. Bourdas, Nickos D. Geladas
Summary: This study examined the effects of breath-hold training on the performance of novice and elite breath-hold divers. The results showed that breath-hold training significantly improved red blood cell concentration, hemoglobin oxygen saturation steady state duration, and breath-hold time in novice divers. Elite divers had better breath-hold performance and higher peak mean arterial pressure compared to novices. The study suggests that breath-hold training can enhance the performance of divers.
RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY
(2024)