Article
Physiology
Jamie C. S. Mccoy, John I. Spicer, Ziad Ibbini, Oliver Tills
Summary: The dynamic nature of developing organisms presents opportunities and challenges for researchers. The information content of the phenotype during organismal development is extensive and relevant to various research questions. However, effectively measuring organismal development and its physiological regulations and functions, and their responses to the environment, remains challenging.
FRONTIERS IN PHYSIOLOGY
(2023)
Article
Developmental Biology
Jordi Garcia-Ojalvo, Aydan Bulut-Karslioglu
Summary: Organisms vary in tissue size and complexity to serve their specific purposes, and correct timing is crucial for tissue development. Premature or delayed differentiation can result in tissue imbalance or malformation. Despite apparent constraints, there is flexibility in timing and differentiation trajectories within and between species.
Review
Physiology
Michael Vaill, Kunio Kawanishi, Nissi Varki, Pascal Gagneux, Ajit Varki
Summary: Anthropogeny is a term used to study the origins of the human species, which involves comparing humans with other hominids and investigating genetic and molecular components. However, the current understanding of genetic differences is not sufficient to explain the distinctive traits that differentiate humans from other hominids. A systematic comparative approach is needed, considering all levels from molecular to physiological to sociocultural.
PHYSIOLOGICAL REVIEWS
(2023)
Article
Medicine, General & Internal
Edem Allado, Mathias Poussel, Anthony Moussu, Veronique Saunier, Yohann Bernard, Eliane Albuisson, Bruno Chenuel
Summary: This study aims to evaluate the value of remote health parameter measurement technology in clinical settings by comparing remote measurements of HR, RR, and SpO(2) with contact measurements in 1045 patients requiring pulmonary function tests. Personal information of patients will be collected, and the accuracy and precision of remote health parameter measurement technology will be assessed using intraclass correlation coefficient analysis.
Article
Ecology
Mathias Dezetter, Andreaz Dupoue, Jean-Francois Le Galliard, Olivier Lourdais
Summary: The study reveals that individuals affected by thermal conditions during the juvenile life stage show changes in metabolic rate and water loss persisting until adulthood, indicating the flexibility of long-lived organisms in adapting to climate change. The research also suggests that physiological syndromes in individuals could play a role in their response to climate change alongside plasticity.
FUNCTIONAL ECOLOGY
(2022)
Article
Biotechnology & Applied Microbiology
Xinyang Li, Moli Yin, Hongmei Wang, Shengbao Duan, Huiyan Wang, Yong Li, Tiemei Liu
Summary: The study found that the hydrogel fluoroimmunoassay can accurately measure fluorescence intensity by flow cytometry, differentiate fetal hemoglobin from adult hemoglobin, and thus provide quantitative prenatal diagnosis of fetal hemoglobin to address the immunological reaction caused by incompatibility between fetal and maternal blood types.
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
(2023)
Article
Agriculture, Multidisciplinary
Weixia Chang, Wei Wang, Zhangsheng Shi, Guodong Cao, Xingchen Zhao, Xiuli Su, Yi Chen, Jiabin Wu, Zhu Yang, Chaolei Liu, Lianguang Shang, Zongwei Cai
Summary: Cadmium pollution poses risks to rice production and human health. NH224 exhibits stronger Cd-tolerance ability compared to NH199, with lower Cd translocation factor. Metabolomic analysis reveals that NH224 has more active amino acids biosynthesis, hormone metabolism, lipids-related metabolism, phenylalanine metabolism, and phenylpropanoid biosynthesis pathways, associated with antioxidant defense, cell wall biosynthesis, phytochelatins synthesis, and plasma membrane stability maintenance.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
(2023)
Article
Plant Sciences
Muhammad Sajid, Muhammad Amjid, Hassan Munir, Muhammad Ahmad, Usman Zulfiqar, Muhammad Fraz Ali, Mohammad Abul Farah, Mohamed A. A. Ahmed, Arkadiusz Artyszak
Summary: Stumpy irrigation water availability is crucial for sugarcane production in Pakistan, but it is hindered by inadequate water distribution and uneven rainfall. The study evaluated sugarcane clones' performance under low water availability in sandy loam soil and identified genotypes with resistance and susceptibility to water deficit. Genotypes S2006-US-658, S2007-AUS-384, and HSF-240 exhibited better physiological traits under water deficit, while CP 77-400, S2008-FD-19, S2006-US-469, and S2003-US-633 showed reduced growth and development under stressed conditions. The study emphasizes that sugarcane can sustain its growth with less irrigation frequency or moisture availability, with certain variations.
Article
Plant Sciences
Yaqiong Wu, Zhengjin Huang, Chunhong Zhang, Chong Shi, Lianfei Lyu, Weilin Li, Wenlong Wu
Summary: This study found that 50% shading can improve the growth index of blueberry and enrich the flavonoid biosynthesis. Additionally, the analysis of the interaction network of differentially expressed proteins revealed key regulatory factors.
FRONTIERS IN PLANT SCIENCE
(2022)
Article
Biology
Rose Y. Y. Zhang, Kristoffer H. Wild, Patrice Pottier, Maider Iglesias Carrasco, Shinichi Nakagawa, Daniel W. A. Noble
Summary: On a global scale, climate change and anthropogenic disturbance pose significant challenges to organisms. Developmental and physiological processes in ectotherms are sensitive to temperature and resource changes. However, the influence of developmental environments on thermal physiology appears to be limited across reptiles, suggesting that behavioral or evolutionary processes may be more important. More research is needed to understand the impacts of changing thermal conditions on reptiles in the future.
Article
Environmental Sciences
Beatriz Fernandez, Juan A. Campillo, Elena Chaves-Pozo, Juan Bellas, Victor M. Leon, Marina Albentosa
Summary: This study compared the role of microplastics and natural organic particles as vehicles for the pesticide chlorpyrifos. Results showed similar capacity for both types of particles to carry the pesticide, with mussels exposed to chlorpyrifos-loaded microplastics displaying similar or more pronounced biological effects after 21 days compared to those exposed to dissolved pesticide or pesticide-loaded natural organic particles.
SCIENCE OF THE TOTAL ENVIRONMENT
(2022)
Article
Biology
Benedicte M. Lefevre, Stecy Mienanzambi, Michael Lang
Summary: The study found that the Sonoran desert endemic species Drosophila pachea is not sensitive to changes in rearing temperature, with similar duration of pupal development at different temperatures. This is likely an evolutionary mechanism to ensure proper development and adaptation to desert climate conditions.
JOURNAL OF THERMAL BIOLOGY
(2022)
Article
Environmental Sciences
Natascha Wosnick, Ana Paula Chaves, Hellida Negrao Dias, Ana Rita Onodera Palmeira Nunes, Jorge Luiz Silva Nunes, Rachel Ann Hauser-Davis
Summary: The current population of Isogomphodon oxyrhynchus (Daggernose Shark) has experienced a 99% decrease in the last decade due to various factors, leading to its listing as Critically Endangered. This study aims to assess the health status of Daggernose sharks and compare it with other shark species to understand their ability to cope with stress. The results show significant differences in the health scores of Daggernose sharks compared to other shark species in the same region, indicating their low recovery capacity.
FRONTIERS IN MARINE SCIENCE
(2023)
Article
Physiology
Jamie C. S. Mccoy, John I. Spicer, Simon D. Rundle, Oliver Tills
Summary: Understanding the links between development and evolution is a major challenge in biology. This study introduces a new approach, called Energy Proxy Traits (EPTs), to quantify organismal development as high-dimensional landscapes of energy spectra in video. The findings show that changes in event timings can influence the high-dimensional phenotypic space, providing a new perspective on the importance of developmental event timing in evolution.
FRONTIERS IN PHYSIOLOGY
(2023)
Article
Physiology
Shakil Ahmad, Momana Jamil, Coline C. Jaworski, Yanping Luo
Summary: Irradiation is a technique that can be used to manage insect pests by impairing their development and leading to mortality. In this study, irradiation was applied to melon fly eggs to identify key genes involved in development and survival. Comparative transcriptomics revealed several upregulated and downregulated genes in irradiated flies compared to non-irradiated flies. Knockdown experiments showed that ImpE2 and Eh_1 genes are essential for the development of melon fly and could potentially be used in RNAi-based pest control strategies.
FRONTIERS IN PHYSIOLOGY
(2023)
Article
Genetics & Heredity
Oliver Tills, Manuela Truebano, Simon Rundle
Article
Ecology
O. Tills, X. Sun, S. D. Rundle, T. Heimbach, T. Gibson, A. Cartwright, M. Palmer, T. Rudin-Bitterli, J. I. Spicer
JOURNAL OF EXPERIMENTAL MARINE BIOLOGY AND ECOLOGY
(2016)
Article
Genetics & Heredity
Manuela Truebano, Oliver Tills, John I. Spicer
Article
Evolutionary Biology
Tilman Schell, Barbara Feldmeyer, Hanno Schmidt, Bastian Greshake, Oliver Tills, Manuela Truebano, Simon D. Rundle, Juraj Paule, Ingo Ebersberger, Markus Pfenninger
GENOME BIOLOGY AND EVOLUTION
(2017)
Article
Genetics & Heredity
Michael Collins, Oliver Tills, John I. Spicer, Manuela Truebano
Article
Biology
Manuela Truebano, Phillip Fenner, Oliver Tills, Simon D. Rundle, Enrico L. Rezende
JOURNAL OF EXPERIMENTAL BIOLOGY
(2018)
Article
Multidisciplinary Sciences
Manuela Truebano, Oliver Tills, Michael Collins, Charlotte Clarke, Emma Shipsides, Charlotte Wheatley, John I. Spicer
SCIENTIFIC REPORTS
(2018)
Article
Multidisciplinary Sciences
Tabitha S. Rudin-Bitterli, Oliver Tills, John I. Spicer, Phil F. Culverhouse, Eric M. Wielhouwer, Michael K. Richardson, Simon D. Rundle
Article
Ecology
Oliver Tills, Manuela Truebano, Barbara Feldmeyer, Markus Pfenninger, Holly Morgenroth, Tilman Schell, Simon D. Rundle
ECOLOGY AND EVOLUTION
(2018)
Article
Biochemistry & Molecular Biology
Oliver Tills, John I. Spicer, Andrew Grimmer, Simone Marini, Vun Wen Jie, Ellen Tully, Simon D. Rundle
Article
Environmental Sciences
Michael Collins, Oliver Tills, Lucy M. Turner, Melody S. Clark, John Spicer, Manuela Truebano
SCIENCE OF THE TOTAL ENVIRONMENT
(2019)
Article
Biology
James C. S. McCoy, John Spicer, Oliver Tills, Simon D. Rundle
JOURNAL OF EXPERIMENTAL BIOLOGY
(2020)
Article
Biochemical Research Methods
Oliver Tills, John I. Spicer, Ziad Ibbini, Simon D. Rundle
Summary: This study tested the biological significance of Energy Proxy Traits (EPTs) in the embryonic development of Radix balthica at different temperatures, finding that EPTs are thermally sensitive and enable effective high-dimensional treatment clustering throughout organismal development. Results suggest that EPTs can capture aspects predictive of biological outcomes, potentially reflecting levels of energy turnover within the phenotype.
BMC BIOINFORMATICS
(2021)
Article
Physiology
Christopher Dwane, Simon D. Rundle, Oliver Tills, Enrico L. Rezende, Juan Galindo, Emilio Rolan-Alvarez, Manuela Truebano
Summary: Thermal stress plays a potentially important role in selective adaptation within intertidal marine habitats. The two ecotypes of Littorina saxatilis in northwest Spain exhibit differences in thermal tolerance across shore height, with the upper-shore ecotype showing greater endurance of thermal stress compared to the lower-shore ecotype. This difference in thermal tolerance may contribute to maintaining population divergence and genetic segregation between the two ecotypes.
PHYSIOLOGICAL AND BIOCHEMICAL ZOOLOGY
(2021)
Article
Biology
Ziad Ibbini, John I. Spicer, Manuela Truebano, John Bishop, Oliver Tills
Summary: HeartCV is an open-source Python package that enables automated measurement of heart rate and heart rate variability across a wide range of species. It integrates automated localization and has been demonstrated to be effective in comparing outputs with manual measurements for species with different heart morphologies. Additionally, its applicability to different experimental approaches and dataset types has been demonstrated.
JOURNAL OF EXPERIMENTAL BIOLOGY
(2022)
Article
Physiology
Alyssa R. Mickle, Jesus D. Penaloza-Aponte, Richard Coffey, Natale A. Hall, David Baekey, Erica A. Dale
Summary: Closed-loop epidural stimulation (CL-ES) can improve respiratory deficits caused by cervical spinal cord injury, restoring diaphragm activity and enhancing contralateral activity. This treatment has the potential to lead to lasting recovery and device independence.
RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY
(2024)
Article
Physiology
Shawn Miller Jr, Edgar Juarez Lopez, Jessica M. L. Grittner, Brendan J. Dougherty
Summary: This study tested the impact of CO2 supplementation at different concentrations on ventilatory long-term facilitation (vLTF) in rats and found that 2% CO2 supplementation during and after acute, intermittent hypoxia (AIH) was sufficient to maintain isocapnia and induce significant vLTF.
RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY
(2024)
Article
Physiology
Behnam Vafadari, Yoshitaka Oku, Charlotte Tacke, Ali Harb, Swen Huelsmann
Summary: The preBo·tzinger Complex (preBo·tC) in the brainstem plays a critical role in generating respiratory rhythm. This study aimed to investigate the activity of inhibitory glycinergic neurons in the preBo·tC of anesthetized mice. Using juxtacellular recordings and optogenetic activation, the researchers were able to identify and characterize the activity pattern of these inhibitory neurons in relation to the breathing rhythm.
RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY
(2024)
Article
Physiology
Stephen M. Johnson, Maia G. Gumnit, Sarah M. Johnson, Tracy L. Baker, Jyoti J. Watters
Summary: Low-level activation of mu-opioid receptors can increase the amplitude of inspiratory bursts in neonatal rat brainstem-spinal cord preparations. Endomorphin-2, an endogenous ligand for these receptors, was found to have similar effects. Disinhibition of inhibitory synaptic transmission may not be involved in the changes induced by endomorphin-2, and different mechanisms may underlie the increase in burst amplitude and decrease in burst frequency.
RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY
(2024)
Article
Physiology
Raphael Martins de Abreu, Beatrice Cairo, Patricia Rehder-Santos, Claudio Donisete da Silva, Etore De Favari Signini, Juliana Cristina Milan-Mattos, Camila Akemi Sakaguchi, Aparecida Maria Catai, Alberto Porta
Summary: The purpose of this study was to determine the association between exercise capacity based on peak oxygen uptake (VO2peak) and resting cardiorespiratory coupling (CRC) levels. The results showed that resting CRC values were associated with exercise capacity in athletes but not in non-athletes.
RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY
(2024)
Article
Physiology
Sarah M. Russel, Raluca E. Gosman, Katherine Gonzalez, Joshua Wright, Dennis O. Frank-Ito
Summary: This study aimed to characterize the response of different nasal morphologies to airflow-related variables during rapid/deep inspiration. The results showed that notched nasal vestibules had higher resistance values and airflow velocities, while standard nasal vestibules had higher mucosal heat flux. Different nasal phenotypes may predispose individuals to exercise-induced rhinitis.
RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY
(2024)
Article
Physiology
Ivan Poliacek, Lukas Martvon, Michal Simera, Marcel Veternik, Jakub Misek, Lucia Cibulkova, Kimberly E. Iceman, Donald C. Bolser, Teresa Pitts
Summary: An animal model study evaluated the effects of an abdominal incision on cough and swallow, revealing that abdominal wall manipulations can increase pharyngeal muscle activity during swallow without affecting the cough reflex. Swallowing tended to occur more during the inspiratory phase. The results highlight the important role of abdominal wall sensory feedback in regulating swallow motor patterns.
RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY
(2024)
Article
Physiology
Rui Yu, Tatsuma Okazaki, Yuzhuo Ren, Junko Okuyama, Satoru Ebihara, Shin-Ichi Izumi
Summary: Body postures significantly influence respiratory muscle force, cough pressure, subjective ease of coughing, and pulmonary function. The 60-degree semi-recumbent posture and sitting posture show better results compared to the supine posture.
RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY
(2024)
Article
Physiology
Suzuna Sato, Koji Ishida, Noriko I. Tanaka, Keisho Katayama
Summary: Respiratory muscle endurance training has beneficial effects on whole-body endurance performance. A novel high-intensity interval (HII) protocol is found to enhance the efficacy of respiratory muscle training programs.
RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY
(2024)
Letter
Physiology
R. Arieli
RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY
(2024)
Correction
Physiology
Ivan Poliacek, Michal Simera, Marcel Veternik, Zuzana Kotmanova, Teresa Pitts, Jan Hanacek, Jana Plevkova, Peter Machac, Nadezda Visnovcova, Jakub Misek, Jan Jakus
RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY
(2024)
Article
Physiology
Dimitrios I. Bourdas, Nickos D. Geladas
Summary: This study examined the effects of breath-hold training on the performance of novice and elite breath-hold divers. The results showed that breath-hold training significantly improved red blood cell concentration, hemoglobin oxygen saturation steady state duration, and breath-hold time in novice divers. Elite divers had better breath-hold performance and higher peak mean arterial pressure compared to novices. The study suggests that breath-hold training can enhance the performance of divers.
RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY
(2024)