Article
Pediatrics
Segundo Rite, Carlos Martin de Vicente, Juan P. Garcia-Iniguez, Maria L. Couce, Maria P. Samper, Alicia Montaner, Carmen Ruiz de la Cuesta
Summary: This study assessed the utility of the 2001 consensus definition of bronchopulmonary dysplasia (BPD) in predicting impaired lung function in preschool-aged children. It found that moderate-to-severe BPD was the best predictor of respiratory impairment, and children with mild BPD showed greater alteration of FEV0.75 than those without BPD.
FRONTIERS IN PEDIATRICS
(2022)
Review
Pediatrics
Kana Ram Jat, Sheetal Agarwal
Summary: Lung function testing is crucial in children for diagnosing and monitoring lung diseases, assessing treatment response, and documenting lung development. Various tests can be performed in different age groups, including infants, although their availability is limited. It is important to perform and interpret the results accurately for optimal treatment and outcome evaluation.
INDIAN JOURNAL OF PEDIATRICS
(2023)
Article
Physiology
Lifei Lu, Jieqi Peng, Ningning Zhao, Fan Wu, Heshen Tian, Huajing Yang, Zhishan Deng, Zihui Wang, Shan Xiao, Xiang Wen, Youlan Zheng, Cuiqiong Dai, Xiaohui Wu, Kunning Zhou, Pixin Ran, Yumin Zhou
Summary: The study found that there was slight agreement between spirometry and impulse oscillometry (IOS) in diagnosing small airway dysfunction (SAD). Spirometry may be more sensitive in detecting SAD patients with abnormal lung function, while IOS may be more sensitive in normal lung function subjects.
FRONTIERS IN PHYSIOLOGY
(2022)
Article
Allergy
Hanna M. Knihtila, Mengna Huang, Nicole Prince, Benjamin J. Stubbs, Vincent J. Carey, Nancy Laranjo, Hooman Mirzakhani, Robert S. Zeiger, Leonard B. Bacharier, George T. O'Connor, Augusto A. Litonjua, Scott T. Weiss, Jessica Lasky-Su
Summary: This study investigated the effects of gestational vitamin D and cumulative tobacco smoke exposure (TSE) throughout pregnancy and early life on child lung function. It found that cumulative TSE was associated with decreased lung function at 6 years, and gestational vitamin D may modulate this effect.
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
(2023)
Article
Respiratory System
Cuiqiong Dai, Fan Wu, Zihui Wang, Jieqi Peng, Huajing Yang, Youlan Zheng, Lifei Lu, Ningning Zhao, Zhishan Deng, Shan Xiao, Xiang Wen, Jianwu Xu, Peiyu Huang, Kunning Zhou, Xiaohui Wu, Yumin Zhou, Pixin Ran
Summary: This study comprehensively assessed the relationship between aging and SAD using computed tomography, impulse oscillometry, and spirometry perspectives.
RESPIRATORY RESEARCH
(2022)
Article
Pediatrics
Bernadette B. L. J. Elders, Harm A. W. M. Tiddens, Marielle W. H. Pijnenburg, Irwin K. M. Reiss, Piotr A. Wielopolski, Pierluigi Ciet
Summary: Magnetic resonance imaging (MRI) can be used for safe imaging assessment of preterm children with and without bronchopulmonary dysplasia (BPD), providing information on structural and functional lung damage that correlates well with spirometry results.
PEDIATRIC PULMONOLOGY
(2022)
Review
Pediatrics
Andrew Fretzayas, Ioanna Loukou, Maria Moustaki, Konstantinos Douros
Summary: Most studies have shown moderate correlations between forced expiratory volume in the first second (FEV1) and other spirometric indices with CT structural lung damage. However, there are patients with normal FEV1 but abnormal CT and vice versa at an individual level. Longitudinal studies indicate that deterioration of structural lung damage does not occur in parallel with lung function progression, and lung clearance index is a better predictor of CT findings.
WORLD JOURNAL OF PEDIATRICS
(2021)
Article
Critical Care Medicine
Anne E. Dixon, Matthew E. Poynter, Olivia Johnson Garrow, David A. Kaminsky, W. G. Tharp, Jason H. T. Bates
Summary: The study investigates the physiological phenotypes of asthma in obesity. It found that physiological responses during bronchoconstriction in people with obesity differ from those simply related to obesity. The study identified two distinct groups of asthma based on respiratory system impedance, suggesting different underlying mechanisms and clinical characteristics.
Article
Medicine, General & Internal
Katarzyna Walicka-Serzysko, Magdalena Postek, Urszula Borawska-Kowalczyk, Justyna Milczewska, Dorota Sands
Summary: This prospective study aimed to assess the course of early lung disease in children with cystic fibrosis (CF) using multiple breath nitrogen washout (MBNW), impulse oscillometry (IOS), and conventional techniques. The results showed that MBNW and IOS are more helpful tools than conventional techniques in evaluating early lung disease in CF. The lung clearance index (LCI) is a more useful parameter than forced expiratory volume in 1 second (FEV1) for detecting functional abnormalities in school-age children.
JOURNAL OF CLINICAL MEDICINE
(2023)
Review
Pediatrics
Shannon Gunawardana, Christopher Harris, Anne Greenough
Summary: Premature birth is a risk factor for bronchopulmonary dysplasia (BPD) and both are linked to obstructive airway disease in childhood. Impulse oscillometry (IOS) is a passive measure of tidal breathing that could be beneficial for assessing lung function in young patients who cannot perform spirometry. Literature search indicates that IOS results correlate with spirometry. The reversibility of airway obstruction in children with BPD varies. IOS could be useful in evaluating individual patient response and suitability for bronchodilator therapy, but more research is needed to establish reference ranges and standardize commercially available devices before routine clinical use.
PAEDIATRIC RESPIRATORY REVIEWS
(2023)
Article
Respiratory System
Hajime Tsuruoka, Hiroshi Handa, Tsuneo Yamashiro, Hiroki Nishine, Takeo Inoue, Masamichi Mineshita
Summary: In patients with Relapsing Polychondritis (RP), Tracheal Volume (TrV) and minimum tracheal cross-sectional area (mtCSA) showed strong correlations with spirometric measurements, while respiratory resistances assessed by impulse oscillometry (IOS) only correlated with TrV. This suggests TrV assessment reflects pulmonary function in RP patients more appropriately than mtCSA.
Review
Respiratory System
Mohammed A. Almeshari, James Stockley, Elizabeth Sapey
Summary: Asthma is a common and chronic disease with significant mortality and morbidity, diagnosis can be difficult due to the lack of a gold standard test. Small airway dysfunction is prevalent in asthma and new therapies targeting the small airways may improve diagnosis and treatment response assessment. Further research is needed to evaluate the utility of small airways tests in asthma.
CHRONIC RESPIRATORY DISEASE
(2021)
Article
Health Care Sciences & Services
Ourania S. Kotsiou, Konstantinos Tourlakopoulos, Lamprini Kontopoulou, Georgios Mavrovounis, Ioannis Pantazopoulos, Paraskevi Kirgou, Sotirios G. Zarogiannis, Zoe Daniil, Konstantinos I. Gourgoulianis
Summary: This study investigated the levels of derivatives-reactive oxygen metabolites (d-ROMs) and plasma antioxidant capacity (PAT) in severe controlled asthmatics and their correlation with lung function. The results showed that d-ROMs and PAT values were higher than normal, indicating oxidative stress in severe controlled asthmatics. Furthermore, D-ROMs were positively correlated with R20 values, suggesting an increase in central airway resistance.
JOURNAL OF PERSONALIZED MEDICINE
(2023)
Article
Critical Care Medicine
Alia Dani, Don Hayes, Amalia Guzman-Gomez, Md Monir Hossain, Jason C. Woods, David L. S. Morales, Russel Hirsch, Farhan Zafar, Erik B. Hysinger
Summary: Patients with bronchopulmonary dysplasia (BPD) may benefit from lung transplant (LTx) as their post-LTx outcomes are similar to those with other diagnoses.
Article
Pediatrics
Qiong Yao, Quan-li Shen, Guo-ying Huang, Xi-hong Hu
Summary: This study found that high-resolution computed tomography (HRCT) scores were related to the severity of bronchopulmonary dysplasia (BPD) and pulmonary hypertension (PH). The hyperaeration score (HS) may be a useful tool in assessing BPD severity, while linear densities and consolidation scores may help predict PH.
FRONTIERS IN PEDIATRICS
(2022)