4.5 Article

Microwave-assisted solid acid-catalyzed synthesis of quinolinyl quinolinones and evaluation of their antibacterial, antioxidant activities

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RESEARCH ON CHEMICAL INTERMEDIATES
卷 41, 期 7, 页码 4899-4912

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SPRINGER
DOI: 10.1007/s11164-014-1575-z

关键词

Quinolinone; 2-Aminobenzophenone; Montmorillonite K-10; Solvent-free conditions; Antibacterial; Antioxidant properties

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Microwave-assisted montmorillonite K-10-catalyzed Friedlander synthesis of quinolinylquinolinones has been developed. The efficient and eco-friendly catalyst along with the convenience of the product isolation make this process an attractive alternative for the synthesis of target heterocycles. The synthesized products were confirmed by FTIR, H-1 NMR, C-13 NMR, and mass spectroscopic techniques. All the synthesized compounds showed good antibacterial property similar to standard Ampicillin and enhanced antioxidant activity.

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