Synthesis and biological evaluation of T-OA analogues as the cytotoxic agents

Betulin, betulinic acid and butein are inhibitors of acetaldehyde-induced activation of liver stellate cells

(2014) Agnieszka Szuster-Ciesielska et al.   Pharmacological Reports

Structural and bioactive studies of terpenes and cyclopeptides from the Genus Rubia

(2013) Kuo Xu et al.   Chemistry Central Journal

Betulinic acid and betulin ameliorate acute ethanol-induced fatty liver via TLR4 and STAT3 in vivo and in vitro

(2013) Ying Wan et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

18α-glycyrrhetinic acid extracted fromGlycyrrhiza radixinhibits proliferation and promotes apoptosis of the hepatic stellate cell line

(2013) Lei Zong et al.   Journal of Digestive Diseases

18α-Glycyrrhetinic Acid Down-Regulates Expression of Type I and III Collagen via TGF-Β1/Smad Signaling Pathway in Human and Rat Hepatic Stellate Cells

(2012) Lei Zong et al.   International Journal of Medical Sciences

Substituted N-Benzylpyrazine-2-carboxamides: Synthesis and Biological Evaluation

(2012) Barbora Servusová et al.   MOLECULES

Synthesis and Biological Evaluation of New Ligustrazine Derivatives as Anti-Tumor Agents

(2012) Penglong Wang et al.   MOLECULES

Dedicated to Professor Kazuhiko Mizuno on the occasion of his retirement

(2012) Gen-ichi Konishi et al.   RESEARCH ON CHEMICAL INTERMEDIATES

NF-κB in the liver—linking injury, fibrosis and hepatocellular carcinoma

(2011) Tom Luedde et al.   Nature Reviews Gastroenterology & Hepatology

Hedgehog Signaling Antagonist Promotes Regression of Both Liver Fibrosis and Hepatocellular Carcinoma in a Murine Model of Primary Liver Cancer

(2011) George M. Philips et al.   PLoS One

Oleanolic Acid and Ursolic Acid Induce Apoptosis in HuH7 Human Hepatocellular Carcinoma Cells through a Mitochondrial-Dependent Pathway and Downregulation of XIAP

(2010) Ming-Huan Shyu et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Ursolic acid ameliorates hepatic fibrosis in the rat by specific induction of apoptosis in hepatic stellate cells

(2010) Xu Wang et al.   JOURNAL OF HEPATOLOGY

Betulin and betulinic acid attenuate ethanol-induced liver stellate cell activation by inhibiting reactive oxygen species (ROS), cytokine (TNF-α, TGF-β) production and by influencing intracellular signaling

(2010) Agnieszka Szuster-Ciesielska et al.   TOXICOLOGY

Addictive evaluation of cholic acid-verticinone ester, a potential cough therapeutic agent with agonist action of opioid receptor

(2009) Jiu-liang Zhang et al.   ACTA PHARMACOLOGICA SINICA

Hsian-tsao (Mesona procumbens Heml.) prevents against rat liver fibrosis induced by CCl4 via inhibition of hepatic stellate cells activation

(2008) Ming-Huan Shyu et al.   FOOD AND CHEMICAL TOXICOLOGY

Structural analysis and antitussive evaluation of five novel esters of verticinone and bile acids

(2008) Jiu-liang Zhang et al.   STEROIDS