Article
Chemistry, Applied
Xinhua Hou, Run Zhang, Man Yang, Naiqi Niu, Junchao Wu, Ze Shu, Pengfei Zhang, Lijun Shi, Fuping Zhao, Ligang Wang, Lixian Wang, Longchao Zhang
Summary: Chinese indigenous pig breeds have higher intramuscular fat content and better meat quality. This study investigated the differential metabolites and lipids in the skeletal muscle of Laiwu and Yorkshire pigs, revealing their association with intramuscular fat content and meat flavor. The results showed that the Laiwu pig had a faster lipid droplet formation and contained more triglyceride, reflecting its higher intramuscular fat content.
Article
Biotechnology & Applied Microbiology
Yan Liu, Huan Long, Simin Feng, Tingting Ma, Mufeng Wang, Lizhu Niu, Xinyi Zhang, Lianni Wang, Yu Lei, Yilong Chen, Qiankun Wang, Xuewen Xu
Summary: This study identified a correlation between intramuscular fat content and gene expression levels in pigs, highlighting the significant role of the AMPK/PPAR signaling pathway in regulating IMF content. Through a combination of QTL mapping and candidate gene identification, novel genes related to IMF content were proposed.
Article
Biochemistry & Molecular Biology
Yueyun Ding, Yinhui Hou, Zijing Ling, Qiong Chen, Tao Xu, Lifei Liu, Na Yu, Wenliang Ni, Xiaoling Ding, Xiaodong Zhang, Xianrui Zheng, Wenbin Bao, Zongjun Yin
Summary: This study assessed the whole transcriptome expression profiles of pigs' Longissimus dorsi muscle with high and low IMF content to identify genes involved in porcine IMF adipogenesis. The findings revealed the involvement of non-coding RNAs in fatty acid metabolic processes, lipid metabolism, and fat cell differentiation. The study also constructed competing endogenous RNAs (ceRNA) regulatory networks, highlighting the roles of lncRNAs, circRNAs, and miRNAs in IMF deposition. These findings provide potential regulators and molecular regulatory networks for future research on IMF traits in pigs, which can aid in improving pork quality through marker-assisted selection.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Genetics & Heredity
Changheng Yang, Qi Li, Yaqiu Lin, Yong Wang, Hengbo Shi, Lian Huang, Wangsheng Zhao, Hua Xiang, Jiangjiang Zhu
Summary: This study reveals the important role of Malonyl-CoA decarboxylase (MCD) in intramuscular fat (IMF) deposition in goats, and its correlation with the expression of multiple genes. The findings contribute to our understanding of the regulatory mechanisms of IMF deposition in goats.
Article
Agriculture, Dairy & Animal Science
Guangjie Xie, Yong Wang, Qing Xu, Meng Hu, Jiangjiang Zhu, Wenlin Bai, Yaqiu Lin
Summary: This study reveals the crucial role of ADIPOQ in regulating intramuscular fat deposition in goats. Knockdown of ADIPOQ promotes the differentiation of intramuscular preadipocytes and accelerates lipid accumulation in mature adipocytes. The study also identifies several key genes involved in this process.
ANIMAL BIOTECHNOLOGY
(2022)
Article
Agriculture, Multidisciplinary
Bojiang Li, Yu He, Wangjun Wu, Xiaofan Tan, Zichenhan Wang, David M. Irwin, Zhe Wang, Shuyi Zhang
Summary: This study investigated the circRNA expression profile in the longissimus dorsi muscle of pigs with high and low IMF content. The results identified differentially expressed circRNAs related to lipid metabolism and adipogenesis processes. Among them, circPPARA was found to be positively correlated with IMF content and promoted intramuscular adipogenesis by adsorbing specific miRNAs. These findings provide valuable insights into the regulatory functions of circRNAs in porcine IMF and offer a resource for future circRNA research in pigs.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
(2022)
Article
Genetics & Heredity
Xiaojin Li, Yanan Yang, Lei Li, Man Ren, Mei Zhou, Shenghe Li
Summary: This study investigated the expression changes in the longissimus dorsi of Wannanhua pigs at different growth stages using transcriptome sequencing technology. Differentially expressed genes (DEGs) associated with lipid metabolism and muscle development were identified, most of which were significantly up-regulated in LD120 and LD240 compared to LD60.
Article
Biotechnology & Applied Microbiology
Wufeng Li, Lixia Qiu, Jiawei Guan, Yutong Sun, Jingwei Zhao, Min Du
Summary: This study explores the regulatory genes that affect IMF content in Guangling donkeys. Transcriptomics analysis reveals differentially expressed genes related to adipocyte differentiation and lipid metabolism. The results provide a basis for further molecular breeding studies.
Article
Agriculture, Dairy & Animal Science
Tong Zhang, Baojun Yu, Zhengyun Cai, Qiufei Jiang, Wei Zhao, Yaling Gu, Juan Zhang
Summary: This study investigates the role of N6-methyladenosine (m6A) modification in the regulation of intramuscular fat (IMF) deposition in poultry. The findings reveal a significant difference in IMF content between the breast and leg, with the leg having higher IMF content. The study identifies differentially methylated genes (DMGs) and pathways associated with IMF deposition, providing important insights for improving meat quality in indigenous chicken breeds.
Article
Food Science & Technology
Tharcilla I. R. C. Alvarenga, David L. Hopkins, Stephen Morris, Peter McGilchrist, Stephanie M. Fowler
Summary: The study aimed to investigate the impact of pH and temperature changes during rigor mortis on the prediction of intramuscular fat (IMF) in lamb carcasses using near infrared (NIR) spectroscopy. Results showed that as muscle temperature decreased post-mortem, there was an enhanced ability of NIR spectra to predict IMF, with spectral measurements at later runs providing more accurate and precise models.
Article
Food Science & Technology
Taiyong Yu, Xuekai Tian, Dong Li, Yulin He, Peiyu Yang, Ye Cheng, Xin Zhao, Jingchun Sun, Gongshe Yang
Summary: In this study, omics methods were used to analyze the differences in meat quality characteristics among Chinese local pig breeds. The results revealed differences in fatty acids, amino acids, gene expression, protein abundance, and metabolite accumulation. Furthermore, the Weighted genes co-expression network construction identified RapGEF1 as a key gene related to intramuscular fat (IMF) content. This study provides fundamental data and new insights into unraveling the mechanism of pig IMF content.
FOOD RESEARCH INTERNATIONAL
(2023)
Article
Agriculture, Dairy & Animal Science
Feng Cheng, Jing Liang, Liyu Yang, Ganqiu Lan, Lixian Wang, Ligang Wang
Summary: Intramuscular fat (IMF) is a key factor affecting meat quality traits of pigs. This study analyzed the expression profiles of various RNAs in the longissimus dorsi muscle, providing insights into the regulatory mechanisms of fat formation at the genomic level. The identification of differentially expressed RNAs related to IMF offers new perspectives for studying the molecular processes involved in fat deposition.
Article
Agriculture, Dairy & Animal Science
Zhiwang Zhang, Tingli Pan, Yu Sun, Siqi Liu, Ziyi Song, Haojie Zhang, Yixing Li, Lei Zhou
Summary: The study showed that calcium addition promotes intramuscular fat accumulation by inhibiting fatty acid oxidation, providing a new approach for increasing intramuscular fat content and improving meat quality.
JOURNAL OF ANIMAL SCIENCE AND BIOTECHNOLOGY
(2021)
Article
Biology
Yifeng Zhang, Yingchun Sun, Zhongzi Wu, Xinwei Xiong, Junjie Zhang, Junwu Ma, Shijun Xiao, Lusheng Huang, Bin Yang
Summary: The study analyzed RNA sequence data for subcutaneous fat (SCF), intramuscular fat (IMF), and longissimus dorsi muscle (LDM) samples from 155 F-6 pigs to investigate gene expression levels and network connectivity. Results showed significant differences in gene expression and network connectivity between SCF and IMF, with tissue-specific genes and network modules associated with fat deposition.
SCIENCE CHINA-LIFE SCIENCES
(2021)
Article
Veterinary Sciences
Xiaofan Tan, Yu He, Yanchun Qin, Zhiwei Yan, Jing Chen, Ruixue Zhao, Shenglan Zhou, David M. Irwin, Bojiang Li, Shuyi Zhang
Summary: Intramuscular fat (IMF) is an important regulator that affects meat quality. This study used quantitative proteomic analysis to identify candidate proteins associated with IMF in donkey muscle. Differentially abundant proteins analysis revealed proteins related to lipid metabolism and adipogenesis.
FRONTIERS IN VETERINARY SCIENCE
(2022)
Article
Veterinary Sciences
R. Mischke, K. Rumstedt, S. O. Hungerbuehler, K. Rohn, M. Schmicke
Summary: Contrast-enhanced ultrasound (CEUS) can provide an additional tool for the diagnosis of hypothyroidism in dogs and support its differentiation from non-thyroidal illness. Sedation has limited impact on CEUS results.
RESEARCH IN VETERINARY SCIENCE
(2024)
Review
Veterinary Sciences
Lucas Petitemberte de Souza, William Borges Domingues, Eduardo Bierhals Blodorn, Leandro da Silva Nunes, Hadassa Gabriela Ortiz, Eliza Rossi Komninou, Vinicius Farias Campos
Summary: This study performed a systematic review of the differential expression of sperm microRNAs in bulls related to fertility. A total of 182 unique differentially expressed miRNAs were identified, among which 49 miRNAs were found in common between at least two studies. The results suggest that miRNAs such as miR-10a, -10b, -103, -15b, -122, -125b, -126-5p, -151-5p, -193a-5p, -196a, -27a-5p, and -99b may serve as potential universal biomarkers for assessing the reproductive potential of males.
RESEARCH IN VETERINARY SCIENCE
(2024)
Article
Veterinary Sciences
Wonhee Cha, Katinca Fungbrant, Giulio Grandi, Ylva Persson
Summary: This study investigated the prevalence and development of hair loss in outdoor cattle in Sweden. It found a relatively high hair loss rate, with the occurrence of hair loss increasing over time during winters, suggesting a contagious etiology. The study also identified preventative delousing before November, keeping animals clean, and maintaining small group sizes as effective measures to reduce the risk of hair loss, while older age and access to bedding materials increased the risk.
RESEARCH IN VETERINARY SCIENCE
(2024)
Article
Veterinary Sciences
Sheeba Thomas, David Francis Lappin, David Bennett, Christopher Nile, Marcello Pasquale Riggio
Summary: This study found that Feline odontoclastic resorptive lesion (FORL) can be divided into two subgroups, with FORL-1 subgroup having a less diverse oral microbiome and higher levels of proinflammatory cytokines and chemokines, which may be associated with the severity and activity of the disease.
RESEARCH IN VETERINARY SCIENCE
(2024)
Article
Veterinary Sciences
S. L. Gayathri, M. Bhakat, T. K. Mohanty
Summary: This study used infrared thermography (IRT) to identify mastitis in Sahiwal cows. The results showed significant differences in the mean values of udder and teat surface temperature between healthy, subclinical mastitis (SCM), and clinical mastitis (CM) cases during different seasons. IRT is an efficient tool for the early identification of subclinical mastitis.
RESEARCH IN VETERINARY SCIENCE
(2024)
Article
Veterinary Sciences
Zeynep Ozdemir Kutahya, Busra Aslan Akyol, Kubra Deliklitas, Cengiz Gokbulut
Summary: In this study, the pharmacokinetic behavior of Eprinomectin was studied in two different goat breeds. The results showed no significant differences in plasma concentration between the breeds, but the clearance from the body may vary. High concentration of Eprinomectin in feces is beneficial against gastrointestinal parasites but poses an ecotoxicological risk to the environment.
RESEARCH IN VETERINARY SCIENCE
(2024)
Article
Veterinary Sciences
Mohammad Ashrafzadeh-Shiraz, Mousa Tavassoli, Bahram Dalir-Naghadeh, Alireza Sazmand
Summary: This study evaluated the efficacy of fenbendazole and ivermectin on strongyles and Parascaris sp. infecting adult riding horses in different regions of Iran. The results demonstrated varying degrees of resistance of these parasites to both anthelminthics. It emphasizes the urgency of educating horse owners about the importance of a test-and-treatment strategy and suggests evaluating the efficacy of different anthelminthics to choose the most effective treatment in each region.
RESEARCH IN VETERINARY SCIENCE
(2024)
Article
Veterinary Sciences
Moises Gonzalvez, Clara Munoz-Hernandez
Summary: The study evaluated the use of R software in research articles addressing the study of wildlife, showing an increasing trend in the number of publications over time and a wide geographical distribution globally.
RESEARCH IN VETERINARY SCIENCE
(2024)