Article
Nutrition & Dietetics
Kelsey M. Cochrane, Jennifer A. Hutcheon, Crystal D. Karakochuk
Summary: This study aimed to assess iron status in early and late pregnancy among pregnant women receiving 27 mg/day of elemental iron. The results showed that despite consuming the recommended amount of iron, there were high rates of iron deficiency. Ethnicity was the only significant factor affecting ferritin concentrations.
JOURNAL OF NUTRITION
(2022)
Article
Nutrition & Dietetics
Anne-Sophie Resseguier, Candy Guiguet-Auclair, Anne Debost-Legrand, Anne-Francoise Serre-Sapin, Laurent Gerbaud, Francoise Vendittelli, Marc Ruivard
Summary: This study aimed to estimate the prevalence of anemia in the third trimester of pregnancy and identify predictive parameters for anemia in the first trimester. The results showed that clinical, social, and biochemical parameters were not effective in predicting anemia in the third trimester. It was suggested to perform a simple blood count in the first trimester and offer oral iron supplementation for women with Hb < 120 g/L.
Review
Nutrition & Dietetics
Shasta A. McMillen, Richard Dean, Eileen Dihardja, Peng Ji, Bo Lonnerdal
Summary: This review summarizes the risks and benefits of iron supplementation during infancy and discusses the underlying mechanisms.
Article
Nutrition & Dietetics
Lucas Gosdin, Andrea J. Sharma, Katie Tripp, Esi Foriwa Amoaful, Abraham B. Mahama, Lilian Selenje, Maria Elena Jefferds, Reynaldo Martorell, Usha Ramakrishnan, O. Yaw Addo
Summary: School-based weekly IFA supplementation in Ghana has been shown to be effective in improving hemoglobin levels and reducing anemia prevalence among schoolgirls. However, most participants did not consume the minimum effective number of IFA tablets, indicating that increasing adherence to intake could further improve anemia outcomes in this population.
JOURNAL OF NUTRITION
(2021)
Article
Environmental Sciences
Zhenxing Chi, Jia Liu, Songwen Tan, Hongwei Lin, Weilin Wu, Weiguo Li
Summary: Phthalic acid esters pose harm to human health by affecting the oxygen-carrying function of red blood cells. High doses of DMP were found to reduce Hb content and increase granulocyte content, while in vitro experiments demonstrated an increase in iron release with DMP concentration. Vitamin C and E were observed to reduce iron release induced by DMP through oxidative stress.
Review
Nutrition & Dietetics
Jordie A. J. Fischer, Arlin M. Cherian, Jeffrey N. Bone, Crystal D. Karakochuk
Summary: This study found that ferrous bisglycinate supplementation, compared to other iron supplements, can increase hemoglobin concentration and reduce gastrointestinal adverse events in pregnant women. However, there was no significant impact on hemoglobin and ferritin concentrations in children. More research is needed to evaluate the efficacy of ferrous bisglycinate compared to other iron supplements in other populations.
Article
Nutrition & Dietetics
Limin Yang, Miori Sato, Mayako Saito-Abe, Makoto Irahara, Minaho Nishizato, Hatoko Sasaki, Mizuho Konishi, Kazue Ishitsuka, Hidetoshi Mezawa, Kiwako Yamamoto-Hanada, Kenji Matsumoto, Yukihiro Ohya
Summary: This study used a large birth cohort in Japan to explore the association of maternal iron status markers with allergy development in offspring, and found no evidence supporting a link between low maternal hemoglobin, hematocrit, or low dietary iron intake with allergy symptoms in early childhood. Further studies with more suitable proxy markers for blood iron status are needed.
Article
Nutrition & Dietetics
Shuting Si, Zhicheng Peng, Haoyue Cheng, Yan Zhuang, Peihan Chi, Xialidan Alifu, Haibo Zhou, Minjia Mo, Yunxian Yu
Summary: The study found a positive association between plasma vitamin D levels and hemoglobin concentration in pregnant women. This association was more significant among women who received iron supplementation during pregnancy.
Article
Obstetrics & Gynecology
Ermias Bekele Wakwoya, Tefera Belachew, Tsinuel Girma
Summary: This study aimed to evaluate the impact of intensive nutrition education and counseling on hemoglobin levels during pregnancy. The results showed that there was a significant change in both hemoglobin levels and the prevalence of anemia in the intervention group. The intervention included trimester-based counseling sessions using the health belief model, weekly SMS reminders containing core messages, and the provision of a leaflet with an iron-rich diet menu. At the end of the trial, the intervention group had significantly higher hemoglobin levels compared to the control group.
BMC PREGNANCY AND CHILDBIRTH
(2023)
Review
Nutrition & Dietetics
Clive J. Petry
Summary: Iron supplementation in pregnancy may increase the risk of gestational diabetes, particularly in women who are already iron-replete. However, current evidence on this topic is contradictory, and the magnitude of any increased risk appears relatively small, urging caution in interpreting the results.
Article
Nutrition & Dietetics
Lulu X. Pei, Hou Kroeun, Suzanne M. Vercauteren, Susan Barr, Tim J. Green, Arianne Y. Albert, Crystal D. Karakochuk
Summary: This study analyzed the predictive value of ten baseline hematological biomarkers for a 12-week hemoglobin response to iron supplementation in Cambodian women. The results showed that Hb measured with a hematology analyzer, inflammation-adjusted ferritin, and hepcidin were strong predictors of Hb response, indicating their potential as indicators for assessing the efficacy of iron supplementation.
JOURNAL OF NUTRITION
(2021)
Article
Medicine, General & Internal
Jiahong Sun, Han Wu, Min Zhao, Costan G. Magnussen, Bo Xi
Summary: Anemia remains a major public health issue in low- and middle-income countries, with high prevalence among children under 5 years old and women of reproductive age, especially younger children and pregnant women. Despite a decreasing trend in anemia prevalence among most countries from 2000-2009 to 2010-2018, the current prevalence remains high, calling for continued and effective efforts to improve the overall health of the population, particularly for high-risk groups.
Article
Orthopedics
Sung-Sahn Lee, Jeounghun Lee, Young-Wan Moon
Summary: This study aimed to investigate the effect of intravenous iron supplementation on the hemoglobin level after staged bilateral total knee arthroplasty (TKA) in patients with or without preoperative anemia. The results showed that there were no significant differences in postoperative hemoglobin levels between patients who received intravenous iron supplementation and those who did not.
BMC MUSCULOSKELETAL DISORDERS
(2023)
Article
Nutrition & Dietetics
Peng Sun, Yueqin Zhou, Suhua Xu, Xiaotong Wang, Xiuxiu Li, Hailin Li, Zongyu Lin, Fenglian Huang, Lewei Zhu, Yanna Zhu
Summary: This study aimed to investigate the association between first-trimester maternal serum hepcidin and third-trimester iron deficiency anemia (IDA). The study found that higher levels of first-trimester hepcidin were negatively associated with the risk of third-trimester IDA, suggesting that elevated hepcidin may predict a reduced risk for developing IDA.
FRONTIERS IN NUTRITION
(2023)
Article
Nutrition & Dietetics
Chih-Wei Tsao, Yuan-Ru Liao, Ting-Chia Chang, Yih-Fong Liew, Chin-Yu Liu
Summary: This study aimed to investigate the effects of iron supplementation on spermatogenesis and testicular functions in iron-deficient rats. The results showed that iron deficiency resulted in poorer spermatogenesis and testis dysfunction, while iron supplementation reversed the impairment and improved antioxidant levels.
Article
Reproductive Biology
Lei Gong, Siyi Jiang, Jia Tian, Yong Li, Wansu Yu, Lubo Zhang, Daliao Xiao
Summary: Exposure to gestational diabetes mellitus during pregnancy can lead to the development of a neonatal brain hypoxia/ischemia-sensitive phenotype. The PTEN/AKT/mTOR/autophagy signaling pathway plays a role in this process.
REPRODUCTIVE TOXICOLOGY
(2024)
Article
Reproductive Biology
Sudipta Dutta, Kirthiram K. Sivakumar, John W. Erwin, Jone A. Stanley, Joe A. Arosh, Robert J. Taylor, Sakhila K. Banu
Summary: This study found that exposure to hexavalent chromium disrupts follicle development and causes apoptosis by altering epigenetic marks in the ovary.
REPRODUCTIVE TOXICOLOGY
(2024)
Article
Reproductive Biology
Yuxin Li, Xianzhi He, Bin Sun, Nannan Hu, Jiamin Li, Ruolan You, Feiyan Tao, Lei Fang, Yuanyuan Li, Qingfeng Zhai
Summary: This study investigated the toxic effects and mechanism of beta-CYP and EMB on the reproductive system of female rats. The results showed that exposure to these pesticides led to changes in hormone and gene expression in the hypothalamic-pituitary-ovarian axis, as well as alterations in oxidative damage indicators. The findings support the evaluation of the adverse effects of pesticide exposure on reproductive health in greenhouse operations.
REPRODUCTIVE TOXICOLOGY
(2024)
Article
Reproductive Biology
Ran Lee, Won-Young Lee, Hyun-Jung Park
Summary: This study investigates the toxicity of diuron on fetal mouse testes and finds that diuron has a negative impact on the development of fetal Leydig cells, while not affecting germ cells and Sertoli cells.
REPRODUCTIVE TOXICOLOGY
(2024)
