期刊
REPRODUCTIVE SCIENCES
卷 21, 期 8, 页码 1034-1043出版社
SPRINGER HEIDELBERG
DOI: 10.1177/1933719114522525
关键词
polycystic ovary syndrome; phenotypes; hyperandrogenism; hirsutism; ultrasonography
资金
- Cornell University
- Strategic Training Initiative in Research in Reproductive Health Sciences, Saskatchewan Health Research Foundation
- Canadian Institutes of Health Research
The prevalence of polycystic ovary syndrome (PCOS) and its distinct clinical phenotypes were assessed using 3 sets of international diagnostic criteria in women self-reporting concerns over outward features of PCOS. Revised ultrasonographic criteria for polycystic ovaries (PCO) based on modern ultrasound technology were used. Of the participants, 53%, 62%, and 70% were diagnosed with PCOS using National Institutes of Health, Androgen Excess and PCOS Society, and Rotterdam criteria, respectively. Prevalence of Frank, Ovulatory, Normoandrogenic, and Non-PCO PCOS were 66%, 13%, 11%, and 9%, respectively. Frank PCOS was associated with the severest metabolic disturbances whereas metabolic profiles in Normoandrogenic PCOS did not differ from controls, supporting reduced health risks in women without androgen excess. Metabolic disturbances and hyperandrogenism were linked to excess adiposity across all the groups. Using updated criteria for PCO, the prevalence of Non-PCO PCOS and PCO alone in healthy women recruited from the general population was reduced compared to the previous reports.
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