Article
Cell Biology
Ajai J. Pulianmackal, Dan Sun, Kenji Yumoto, Zhengda Li, Yu-Chih Chen, Meha V. Patel, Yu Wang, Euisik Yoon, Alexander Pearson, Qiong Yang, Russell Taichman, Frank C. Cackowski, Laura A. Buttitta
Summary: The decision between proliferation and quiescence in the cell cycle is a dynamic process with high heterogeneity, even among clonal cell lines. Spontaneous entry into G0 states, which can lead to tumor dormancy and cancer recurrence, is influenced by both intrinsic and extrinsic signals, including asymmetric proliferation-quiescence decisions after mitosis. Dormant cancer cells exhibit altered expression of certain pathways and stem cell markers, potentially increasing the risk of cancer recurrence.
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY
(2021)
Article
Biology
Fernanda Moura, Leticia Sampaio, Priscila Kobayashi, Renee Laufer-Amorim, Joao Carlos Ferreira, Tatiane Terumi Negrao Watanabe, Carlos E. Fonseca-Alves
Summary: The study characterized the morphology, histochemical, immunohistochemical, and ultrastructural features of the giant anteater prostate gland. It was found that the adult giant anteater prostate gland is divided into central and peripheral zones, and immunohistochemical characterization revealed a pattern similar to the human prostate.
Article
Engineering, Electrical & Electronic
Zhaorui Wang, Ya-Feng Liu, Liang Liu
Summary: This letter studies the joint device activity and delay detection problem in asynchronous massive machine-type communications. A covariance-based approach is proposed to solve the problem, and it outperforms the existing compressed sensing approach in terms of detection performance.
IEEE SIGNAL PROCESSING LETTERS
(2022)
Article
Agriculture, Dairy & Animal Science
C. B. Reed, B. Kuhn-Sherlock, C. R. Burke, S. Meier
Summary: This observational study aimed to investigate the effect of genetic merit for fertility traits on estrous expression and duration in grazing dairy cows. The study found that cows with positive genetic merit for fertility traits exhibited more active and longer estrous events. These findings are important for improving estrous detection in commercial herds.
JOURNAL OF DAIRY SCIENCE
(2022)
Article
Engineering, Electrical & Electronic
Yang Li, Qingfeng Lin, Ya-Feng Liu, Bo Ai, Yik-Chung Wu
Summary: This paper proposes an equivalent reformulation to address the asynchronous activity detection problem and develops centralized and distributed algorithms. Simulation results demonstrate that the proposed algorithms outperform existing approaches.
IEEE TRANSACTIONS ON WIRELESS COMMUNICATIONS
(2023)
Article
Computer Science, Information Systems
Roberto B. Di Renna, Rodrigo C. de Lamare
Summary: The letter presents a joint active device detection and channel estimation framework based on factor graphs, and introduces the MSGAMP algorithm for this purpose. The MSGAMP algorithm shows good performance in terms of activity error rate and mean squared error, with fewer iterations and lower complexity compared to state-of-the-art techniques.
IEEE WIRELESS COMMUNICATIONS LETTERS
(2021)
Article
Multidisciplinary Sciences
Congcong Liu, Sophie Yue, Joshua Solarz, Jessica Lee, Lei Li
Summary: The study found that high levels of testosterone caused PCOS fish to exhibit symptoms such as follicular growth-arrest and rare ovulation, leading to decreased sexual activity. However, the sexuality levels and mating rate of PCOS fish could be improved through short periods of rearing in conditions that lack of males.
SCIENTIFIC REPORTS
(2021)
Review
Reproductive Biology
Diana Elizabeth Alcantara-Zapata, Anibal J. Llanos, Carolina Nazzal
Summary: Living at high altitudes and suffering from prostatic illness are both closely related to a hypoxic environment, potentially leading to oxygen scarcity and high oxygen demand. This similarity may suggest that hypobaric hypoxia and other common factors could contribute to the aggravation of prostatic disease, but there is currently a lack of evidence regarding males in high-altitude areas.
BIOLOGY OF REPRODUCTION
(2021)
Article
Neurosciences
Chuangeng Zhang, Meijian Wang, Shengyin Lin, Ruili Xie
Summary: The study reveals that Calretinin is selectively expressed in different subtypes, affecting synaptic efficacy and recovery speed, contributing to reduce calcium accumulation during high-rate activity. Synapses with differential CR expression exhibit differences in synaptic transmission and VGluT expression, influencing their ability to transmit auditory information.
JOURNAL OF NEUROSCIENCE
(2022)
Article
Automation & Control Systems
Mahmoud S. Assran, Michael G. Rabbat
Summary: This study introduces a multiagent framework for distributed optimization, in which each agent accesses a local function and converges to the global minimum using an asynchronous algorithm. Numerical experiments demonstrate that asynchronous gradient push achieves faster global minimization and better scalability with network size compared to synchronous methods.
IEEE TRANSACTIONS ON AUTOMATIC CONTROL
(2021)
Article
Genetics & Heredity
Anamay Shetty, Ji-Heui Seo, Connor A. Bell, Edward P. O'Connor, Mark M. Pomerantz, Matthew L. Freedman, Alexander Gusev
Summary: Integration of epigenomic data from tumor and normal tissues has identified risk-harboring regulatory elements for prostate cancer, with some risk variants showing significant allele specificity in tumors. These findings suggest a role for tumor-specific regulation in cancer risk and highlight potential causal regulatory elements at GWAS loci.
AMERICAN JOURNAL OF HUMAN GENETICS
(2021)
Article
Fisheries
Kate Seinor, Steven W. Purcell, Hamish Malcolm, Stephen D. A. Smith, Kirsten Benkendorff
Summary: This study investigated the reproductive cycle of the Australian turbinid, Turbo militaris, and found that it has an extended pattern of reproduction that is closely related to environmental conditions. The findings of this study are important for the development of fisheries management measures.
FISHERIES OCEANOGRAPHY
(2024)
Article
Agriculture, Multidisciplinary
Ge Shi-shuai, He Wei, He Li-mei, Yan Ran, Zhang Hao-wen, Wu Kong-ming
Summary: The study found that appropriate flight activity of the fall armyworm significantly speeds up the reproductive process, enhancing our understanding of its migratory biology.
JOURNAL OF INTEGRATIVE AGRICULTURE
(2021)
Article
Computer Science, Information Systems
Wei Zhang, Jiahui Li, Xiujun Zhang, Shidong Zhou
Summary: This study proposes a novel approach to achieve low-latency GF access under imperfect conditions by improving the algorithm and frame structure. This method is of great significance for meeting the low-latency requirement in massive access of short packets.
IEEE WIRELESS COMMUNICATIONS LETTERS
(2022)
Article
Automation & Control Systems
Rongping Zhu, Jiaqi Zhang, Keyou You, Tamer Basar
Summary: We propose a fully asynchronous networked aggregative game (Asy-NAG) where each player minimizes a local cost function that depends on its own action and the aggregate of all players' actions. In contrast to existing NAGs, our Asy-NAG allows each player to compute an estimate of the aggregate action at any wall-clock time using potentially outdated information from neighboring players. The game does not require coordination among players and incorporates a novel distributed algorithm that adjusts optimization stepsize adaptively per update. We address asynchronicity and information delays between players using an augmented network approach and rigorously prove convergence to a Nash equilibrium of the Asy-NAG via a perturbed coordinate algorithm.
Article
Anatomy & Morphology
Lara Zacari Fanali, Juliane Silberschmidt Freitas, Lilian Franco-Belussi, Sebastiao Roberto Taboga, Classius de Oliveira
Summary: This study described the morphological aspects of liver in three Neotropical anuran species and found that their anatomical and ultrastructural features are quite similar, but with differences in structural arrangements in histology. Understanding the hepatic morphology and ultrastructure in amphibians is crucial for detecting changes in experimental studies and inferring possible physiological or metabolic changes under adverse conditions.
Review
Cell Biology
Bruno Domingos Azevedo Sanches, Guilherme Henrique Tamarindo, Juliana Dos Santos Maldarine, Alana Della Torre Da Silva, Vitoria Alario Dos Santos, Rejane Maira Goes, Sebastiao Roberto Taboga, Hernandes F. Carvalho
Summary: The male urogenital system consists of the reproductive and urinary systems, sharing interconnected embryonic development and anatomical components. Telocytes are possibly key in stromal tissue maintenance in the urogenital system, with roles in stem cell niches, immune system interactions, and specific functions in organs such as the testes, kidneys, and bladder. They are also implicated in pathologies in various organs within the system.
CELL BIOLOGY INTERNATIONAL
(2021)
Article
Environmental Sciences
Danilo da Silva Lima, Liana da Silva Gomes, Esther de Sousa Figueredo, Yasmin Inocencio Fernandes E. Silva, Edvaldo Mendes Silva, Thais de Souza Bovi, Sebastiao Roberto Taboga, Mara Rubia Marques, Manoel Francisco Biancardi, Fernanda Cristina Alcantara dos Santos
Summary: The study found that aluminum has harmful effects on the prostate of gerbils, with high toxicity and estrogenic agonistic effects. After 30 days of exposure, male gerbils showed partial recovery of the prostate, while female gerbils showed less improvement in prostate morphology.
ENVIRONMENTAL TOXICOLOGY
(2022)
Article
Physiology
Lucas J. S. Greville, Larissa M. Bueno, Tyler Pollock, Paul A. Faure
Summary: This study reports the first urinary steroid profile in bats by quantifying 17 beta-estradiol (E-2) levels in captive male and female E. fuscus across their reproductive cycle. The research found that male bats had higher urinary E-2 levels than females, and adults had higher levels than yearlings. Seasonal differences in urinary E-2 levels were observed in nonpregnant females. These findings are important for understanding the reproductive cycling in bats.
PHYSIOLOGICAL AND BIOCHEMICAL ZOOLOGY
(2022)
Article
Cell Biology
Juliana S. Maldarine, Bruno D. A. Sanches, Vitoria A. Santos, Rejane M. Goes, Patricia S. L. Vilamaior, Hernandes F. Carvalho, Sebastiao R. Taboga
Summary: This study investigates the presence of telocytes in the female prostate and their role in tumorigenesis. The results show that telocytes are important for maintaining smooth muscle and prostatic epithelium integrity, but they are also associated with immune cells, suggesting a complex role in prostatic tumorigenesis in females.
CELL BIOLOGY INTERNATIONAL
(2022)
Article
Endocrinology & Metabolism
Gustavo M. Amaro, Alana D. T. da Silva, Guilherme H. Tamarindo, Celina de A. Lamas, Sebastiao R. Taboga, Valeria Helena Alves Cagnon, Rejane M. Goes
Summary: In vitro studies have shown that omega-3 polyunsaturated fatty acids ([n-3] PUFAs) have antitumor effects, but their effects on prostate cancer remain controversial in epidemiological studies. This study found that a(n-3) PUFA-enriched diet could delay tumor progression in the early stages of prostate cancer in mice and reduce cell proliferation and hormone receptor expression.
Article
Endocrinology & Metabolism
Silvana G. P. Campos, Bianca F. Goncalves, Thalles Fernando Rocha Ruiz, Ellen Cristina R. Leonel, Daniele L. Ribeiro, Luiz Roberto Falleiros Junior, Rejane M. Goes, Sebastiao R. Taboga
Summary: This study evaluated changes in proteoglycan morphology and composition in the prostatic stroma of castrated gerbils. Results showed an increase in chondroitin sulfate frequency after androgen blockade and an increase in perlecan content. The length and shape of proteoglycans were also altered. These findings suggest that proteoglycans might respond to androgen deprivation independently of androgenic regulation.
Article
Developmental Biology
Tatiane Pereira Scarpelli, Eloisa Zanin Pytlowanciv, Maria Etelvina Pinto-Fochi, Sebastiao Roberto Taboga, Rejane Maira Goes
Summary: Maternal obesity and high-fat diet during breastfeeding lead to stromal hyperplasia and diffuse acinar atrophy in the aging rat prostate, which is closely related to dyslipidemia and reduced testosterone levels. The high-lipid nutritional environment from intrauterine and throughout life facilitates the development of prostatic intraepithelial neoplasia and worsens degenerative changes in the gland.
Article
Anatomy & Morphology
Pollyana B. Pimentel, Juliana Filgueira Ferraz, Cornelio Souza Santigo, Emilia Miguel Soares, Eliana Morielle-Versute, Sebastiao R. Taboga, Carolina C. Souza, Mateus R. Beguelini
Summary: Despite being highly diverse and widely distributed, the reproductive accessory glands (RAGs) of bats have received limited attention in research. This study aimed to analyze and compare the composition, anatomy, and histology of male RAGs in three cosmopolitan bat families (Vespertilionidae, Molossidae, and Emballonuridae). The results revealed that the RAGs of these bat species consist of an intra-abdominal prostatic complex, urethral glands, and inguinal bulbourethral glands, but lack ampullary glands or seminal vesicles. The prostatic complex varies in the number of regions and lobed structure among the species.
ANATOMICAL RECORD-ADVANCES IN INTEGRATIVE ANATOMY AND EVOLUTIONARY BIOLOGY
(2023)
Article
Cell Biology
Liana Silva Gomes, Danilo da Silva Lima, Janaina Ribeiro Costa, Jane Sousa Naves, Mara Rubia Marques, Sebastiao Roberto Taboga, Paulo Cesar Ghedini, Manoel Francisco Biancardi, Fernanda Cristina Alcantara dos Santos
Summary: This study evaluated the effects of aluminum neonatal exposure on the male and female gerbil prostates. Results showed that adult male prostates exhibited moderate hyperplasia and increased cell proliferation, while senile males showed intense hyperplasia. Additionally, there was a reduction in prostate secretory function at both ages. Female prostates exhibited similar morphological changes to males, with adult females showing a lower regulation of androgen receptor and estrogen receptor alpha, and senile females showing intense hyperplastic growth with an increase in estrogen receptor alpha and a reduction in stromal androgen receptor.
CELL BIOLOGY INTERNATIONAL
(2023)
Review
Obstetrics & Gynecology
Thalles Fernando Rocha Ruiz, Patricia Simone Leite Vilamaior, Vitor Grigio, Simone Jacovaci Colleta, Mariele Ilario Zucao, Silvana Gisele Pegorin de Campos, Fernanda Cristina Alcantara dos Santos, Manoel Francisco Biancardi, Ana Paula Silva Perez, Sebastiao Roberto Taboga, Ellen Cristina Rivas Leonel
Summary: Mongolian gerbils have significant roles in biological and biomedical experiments, especially in physiological and pharmacological studies, as well as in research on nervous, digestive, auditory systems, microbiology, and parasitology. They have also been applied for studying carcinogenesis and reproductive aspects, providing valuable information and recent findings as an alternative to inbred mice and rats. Gerbils have contributed to expanding knowledge in prostate biology, spermiogenesis, mammary gland alterations, and ovarian cysts, among other areas.
REPRODUCTIVE SCIENCES
(2023)
Article
Cell Biology
Thalles F. R. Ruiz, Simone J. Colleta, Diego D. dos Santos, Nayara F. C. Castro, Agata S. Cabral, Marilia F. Calmon, Paula Rahal, Cristiane D. Gil, Ana Paula Girol, Patricia S. L. Vilamaior, Ellen C. R. Leonel, Sebastiao R. Taboga
Summary: Inflammation in the established tumor microenvironment is often associated with poor prognosis of breast cancer. This study aims to investigate the inflammatory repercussions of bisphenol A (BPA) in the mammary gland during neoplastic development in aging. The results show that BPA induces carcinogenic development and promotes polarization of macrophages and mast cells in the tumor microenvironment.
CELL BIOLOGY INTERNATIONAL
(2023)
Article
Cell Biology
Thalles F. R. Ruiz, Vitor Grigio, Luara J. Ferrato, Lorena G. de Souza, Simone J. Colleta, Gustavo M. Amaro, Rejane M. Goes, Patricia S. L. Vilamaior, Ellen C. R. Leonel, Sebastia O. R. Taboga
Summary: This study demonstrates that exposure of pregnant and lactating women to the endocrine disruptor bisphenol A (BPA) can impact their ovarian function and accelerate aging of the ovaries. Ovaries exposed to BPA showed impaired follicle development and disruption in hormone signaling. BPA exposure also affected steroidogenesis, leading to decreased levels of estrogen and testosterone. These changes play a significant role in follicular development and contribute to perimenopausal and infertile features.
MOLECULAR AND CELLULAR ENDOCRINOLOGY
(2023)
Article
Biotechnology & Applied Microbiology
Bruna Maria Salotti de Souza, Luiz Henrique Alves Guerra, Giovanna Rossi Varallo, Sebastiao Roberto Taboga, Ana Lucia Barretto Penna
Summary: This study evaluated the effects of consuming milk fermented by Lacticaseibacillus (Lc.) casei SJRP38 and Limosilactobacillus (Lm.) fermentum SJRP43 on bacterial translocation, stool analysis, and intestinal morphology in healthy BALB/c mice. The results showed that fermented milk containing these strains promoted a healthier microbiota and improved the intestinal condition.
PROBIOTICS AND ANTIMICROBIAL PROTEINS
(2023)
