Epigenetic reprogramming: is deamination key to active DNA demethylation?

Thymine DNA Glycosylase Is Essential for Active DNA Demethylation by Linked Deamination-Base Excision Repair

(2011) Salvatore Cortellino et al.   CELL

Hydroxylation of 5-Methylcytosine by TET1 Promotes Active DNA Demethylation in the Adult Brain

(2011) Junjie U. Guo et al.   CELL

The RNA Exosome Targets the AID Cytidine Deaminase to Both Strands of Transcribed Duplex DNA Substrates

(2011) Uttiya Basu et al.   CELL

Tet1 and Tet2 Regulate 5-Hydroxymethylcytosine Production and Cell Lineage Specification in Mouse Embryonic Stem Cells

(2011) Kian Peng Koh et al.   Cell Stem Cell

Embryonic lethal phenotype reveals a function of TDG in maintaining epigenetic stability

(2011) Daniel Cortázar et al.   NATURE

TET1 and hydroxymethylcytosine in transcription and DNA methylation fidelity

(2011) Kristine Williams et al.   NATURE

Hotspots of aberrant epigenomic reprogramming in human induced pluripotent stem cells

(2011) Ryan Lister et al.   NATURE

Dynamic regulation of 5-hydroxymethylcytosine in mouse ES cells and during differentiation

(2011) Gabriella Ficz et al.   NATURE

Dual functions of Tet1 in transcriptional regulation in mouse embryonic stem cells

(2011) Hao Wu et al.   NATURE

Reprogramming of the paternal genome upon fertilization involves genome-wide oxidation of 5-methylcytosine

(2011) Khursheed Iqbal et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

5-Hydroxymethylcytosine in the mammalian zygote is linked with epigenetic reprogramming

(2011) Mark Wossidlo et al.   Nature Communications

Smad Signaling Is Required to Maintain Epigenetic Silencing during Breast Cancer Progression

(2010) P. Papageorgis et al.   CANCER RESEARCH

Activation-Induced Cytidine Deaminase Targets DNA at Sites of RNA Polymerase II Stalling by Interaction with Spt5

(2010) Rushad Pavri et al.   CELL

DNA Demethylase Activity Maintains Intestinal Cells in an Undifferentiated State Following Loss of APC

(2010) Kunal Rai et al.   CELL

APOBEC2, a selective inhibitor of TGFβ signaling, regulates left–right axis specification during early embryogenesis

(2010) Alin Vonica et al.   DEVELOPMENTAL BIOLOGY

Dynamic link of DNA demethylation, DNA strand breaks and repair in mouse zygotes

(2010) Mark Wossidlo et al.   EMBO JOURNAL

In pursuit of the first recognized epigenetic signal––DNA methylation: A 1976 to 2008 synopsis

(2010) Walter Doerfler   Epigenetics

Conserved DNA methylation inGadd45a-/-mice

(2010) Nora Engel et al.   Epigenetics

Interaction of noncoding RNA with the rDNA promoter mediates recruitment of DNMT3b and silencing of rRNA genes

(2010) K.-M. Schmitz et al.   GENES & DEVELOPMENT

Regulation of human endogenous retrovirus-K expression in melanomas by CpG methylation

(2010) Sven Stengel et al.   GENES CHROMOSOMES & CANCER

Impaired hydroxylation of 5-methylcytosine in myeloid cancers with mutant TET2

(2010) Myunggon Ko et al.   NATURE

Genome-wide erasure of DNA methylation in mouse primordial germ cells is affected by AID deficiency

(2010) Christian Popp et al.   NATURE

A role for the elongator complex in zygotic paternal genome demethylation

(2010) Yuki Okada et al.   NATURE

Role of Tet proteins in 5mC to 5hmC conversion, ES-cell self-renewal and inner cell mass specification

(2010) Shinsuke Ito et al.   NATURE

Gemcitabine Functions Epigenetically by Inhibiting Repair Mediated DNA Demethylation

(2010) Andrea Schäfer et al.   PLoS One

Identification of RING finger protein 4 (RNF4) as a modulator of DNA demethylation through a functional genomics screen

(2010) X. V. Hu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Genome-Wide Reprogramming in the Mouse Germ Line Entails the Base Excision Repair Pathway

(2010) P. Hajkova et al.   SCIENCE

Epigenetic Reprogramming in Plant and Animal Development

(2010) Suhua Feng et al.   SCIENCE

Histone H3 lysine 4 methylation is associated with the transcriptional reprogramming efficiency of somatic nuclei by oocytes

(2010) Kazutaka Murata et al.   Epigenetics & Chromatin

Active DNA Demethylation Mediated by DNA Glycosylases

(2009) Jian-Kang Zhu   Annual Review of Genetics

DNA Repair in Mammalian Cells

(2009) C. Kunz et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Active DNA demethylation and DNA repair

(2009) Christof Niehrs   DIFFERENTIATION

Deficiency in APOBEC2 Leads to a Shift in Muscle Fiber Type, Diminished Body Mass, and Myopathy

(2009) Yusuke Sato et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

S region sequence, RNA polymerase II, and histone modifications create chromatin accessibility during class switch recombination

(2009) Lili Wang et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The activation-induced cytidine deaminase (AID) efficiently targets DNA in nucleosomes but only during transcription

(2009) Hong Ming Shen et al.   JOURNAL OF EXPERIMENTAL MEDICINE

TAF12 Recruits Gadd45a and the Nucleotide Excision Repair Complex to the Promoter of rRNA Genes Leading to Active DNA Demethylation

(2009) Kerstin-Maike Schmitz et al.   MOLECULAR CELL

Implications of epigenetics and genomic imprinting in assisted reproductive technologies

(2009) Shari L. Laprise   MOLECULAR REPRODUCTION AND DEVELOPMENT

DNA demethylation in hormone-induced transcriptional derepression

(2009) Mi-Sun Kim et al.   NATURE

Human DNA methylomes at base resolution show widespread epigenomic differences

(2009) Ryan Lister et al.   NATURE

Reprogramming towards pluripotency requires AID-dependent DNA demethylation

(2009) Nidhi Bhutani et al.   NATURE

Specific recruitment of protein kinase A to the immunoglobulin locus regulates class-switch recombination

(2009) Bao Q Vuong et al.   NATURE IMMUNOLOGY

Active nuclear import and cytoplasmic retention of activation-induced deaminase

(2009) Anne-Marie Patenaude et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Conversion of 5-Methylcytosine to 5-Hydroxymethylcytosine in Mammalian DNA by MLL Partner TET1

(2009) M. Tahiliani et al.   SCIENCE

Multiplex RT-PCR Expression Analysis of Developmentally Important Genes in Individual Mouse Preimplantation Embryos and Blastomeres1

(2008) Andreas May et al.   BIOLOGY OF REPRODUCTION

DNA Cytosine Demethylation: Are We Getting Close?

(2008) Josef Jiricny et al.   CELL

DNA Demethylation in Zebrafish Involves the Coupling of a Deaminase, a Glycosylase, and Gadd45

(2008) Kunal Rai et al.   CELL

Tissue specific differentially methylated regions (TDMR): Changes in DNA methylation during development

(2008) Fei Song et al.   GENOMICS

Coordinating the Initial Steps of Base Excision Repair

(2008) Megan E. Fitzgerald et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Proteasomal degradation restricts the nuclear lifespan of AID

(2008) Said Aoufouchi et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Cyclical DNA methylation of a transcriptionally active promoter

(2008) Raphaël Métivier et al.   NATURE

Chromatin dynamics during epigenetic reprogramming in the mouse germ line

(2008) Petra Hajkova et al.   NATURE

Crystal structure of human thymine DNA glycosylase bound to DNA elucidates sequence-specific mismatch recognition

(2008) Atanu Maiti et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mammalian DNA Methyltransferases: A Structural Perspective

(2008) Xiaodong Cheng et al.   STRUCTURE

GADD45A Does Not Promote DNA Demethylation

(2008) Seung-Gi Jin et al.   PLoS Genetics

Activation-induced deaminase, AID, is catalytically active as a monomer on single-stranded DNA

(2007) Sukhdev S. Brar et al.   DNA REPAIR