Article
Cardiac & Cardiovascular Systems
Peter Ladlow, Oliver O'Sullivan, Andrew Houston, Robert Barker-Davies, Samantha May, Daniel Mills, Dominic Dewson, Rebecca Chamley, Jon Naylor, Joseph Mulae, Alexander N. Bennett, Edward D. Nicol, David A. Holdsworth
Summary: This study found that dysautonomia after COVID-19 is associated with objective functional limitations, but not with subjective symptoms or limitations.
Article
Physiology
Jinelle Gelinas, Megan Harper, John Sasso, Stephen Wright, Bernie Melzer, Gloria Agar, Jordan Guenette, Gregory duManoir, Michael Roman, J. Douglass Rolf, Neil Eves
Summary: This study investigated the integrative exercise responses associated with different exercise limitation phenotypes in COPD patients. The results showed that the cardiovascular phenotype had less static hyperinflation, lower end-expiratory lung volume, and larger tidal volume during exercise compared to other phenotypes. The cardiovascular phenotype also showed higher peak ventilation, cardiopulmonary fitness, and maximum workload compared to the ventilatory phenotype. Categorizing COPD patients phenotypically may aid in optimizing exercise prescription for rehabilitation purposes.
FRONTIERS IN PHYSIOLOGY
(2022)
Article
Geriatrics & Gerontology
Shalender Bhasin, Venkatesh Krishnan, Thomas W. Storer, Mitchell Steiner, Adrian S. Dobs
Summary: Testosterone, other androgens, and nonsteroidal SARMs are being developed as therapies to treat functional limitations associated with aging and chronic diseases. They have shown anabolic effects on muscle mass and strength in various populations. Testosterone treatment also has positive effects on bone health, sexual function, and depressive symptoms. However, the cardiovascular and prostate safety of testosterone still needs further investigation. Future studies should focus on translating muscle gains into functional improvements through combined administration with exercise.
JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES
(2023)
Review
Rheumatology
Aleksandra R. Budarick, Rebecca F. Moyer
Summary: The study reviewed evidence published from the Osteoarthritis Initiative (OAI) linking physical activity with clinical, functional, and structural knee osteoarthritis outcomes. Positive effects of physical activity were consistently reported in clinical and functional outcomes, with limited impact on structural outcomes. The evidence maps generated serve as a framework for future investigations into the effects of physical activity on knee osteoarthritis.
CLINICAL RHEUMATOLOGY
(2022)
Article
Multidisciplinary Sciences
Odette Leiter, David Brici, Stephen J. Fletcher, Xuan Ling Hilary Yong, Jocelyn Widagdo, Nicholas Matigian, Adam B. Schroer, Gregor Bieri, Daniel G. Blackmore, Perry F. Bartlett, Victor Anggono, Saul A. Villeda, Tara L. Walker
Summary: Physical activity has beneficial effects on brain ageing, and platelets secrete an anti-geronic exerkine that mediates the rejuvenating effects of exercise.
NATURE COMMUNICATIONS
(2023)
Article
Multidisciplinary Sciences
Odette Leiter, David Brici, Stephen J. Fletcher, Xuan Ling Hilary Yong, Jocelyn Widagdo, Nicholas Matigian, Adam B. Schroer, Gregor Bieri, Daniel G. Blackmore, Perry F. Bartlett, Victor Anggono, Saul A. Villeda, Tara L. Walker
Summary: Exercise has positive effects on the aging brain, and platelet-released exerkines, such as PF4, mediate these effects. Platelets are activated by exercise and are necessary for exercise-induced increase in precursor cell proliferation in the hippocampus of aged mice. Increasing the levels of the platelet-derived exerkine PF4 improves age-related cognitive impairments through hippocampal neurogenesis. These findings emphasize the role of platelets in the rejuvenating effects of exercise during brain aging.
NATURE COMMUNICATIONS
(2023)
Article
Geriatrics & Gerontology
Sara A. Harper, John R. Bassler, Sujitha Peramsetty, Youfeng Yang, Lisa M. Roberts, Devin Drummer, Robert T. Mankowski, Christiaan Leeuwenburgh, Karina Ricart, Rakesh P. Patel, Marcas M. Bamman, Stephen D. Anton, Byron C. Jaeger, Thomas W. Buford
Summary: The study aimed to evaluate the safety and feasibility of combining exercise and resveratrol to treat older adults, showing that this combined treatment may improve skeletal muscle mitochondrial function and mobility-related indices of physical function. A larger trial is warranted to further validate these findings.
EXPERIMENTAL GERONTOLOGY
(2021)
Article
Ethnic Studies
Christopher S. Walter, Marie-Rachelle Narcisse, Jennifer L. Vincenzo, Holly C. Felix, Pearl A. McElfish
Summary: The study found that NHPI adults who met the guidelines for aerobic and strengthening physical activity experienced fewer difficulties in functional limitations, especially in two constructs. Those who met only the aerobic guideline reported fewer difficulties in all three FL constructs. Adults who met both guidelines had the least difficulties in all three constructs.
ETHNICITY & HEALTH
(2022)
Article
Gerontology
Maxwell J. Rakutt, Ryan A. Mace, Caitlin E. W. Conley, Austin V. Stone, Stephen T. Duncan, Jonathan Greenberg, David C. Landy, Ana-Maria Vranceanu, Cale A. Jacobs
Summary: This study aimed to assess the association between osteoarthritis (OA), functional impairment, and cognitive impairment in the aging population. The results showed that functional limitations were associated with cognitive impairment, regardless of OA diagnosis, while OA itself was not independently associated with cognitive impairment.
JOURNAL OF AGING AND HEALTH
(2023)
Article
Multidisciplinary Sciences
Eiichiro Kanda, Marcelo Barreto Lopes, Kazuhiko Tsuruya, Hideki Hirakata, Kunitoshi Iseki, Angelo Karaboyas, Brian Bieber, Stefan H. Jacobson, Indranil Dasgupta, Bruce M. Robinson
Summary: The study found that the combination of Malnutrition-Inflammation-Complex (MIC) and low functional status (FS) is strongly associated with mortality in hemodialysis patients. Identification of MIC and poor FS may help decrease adverse clinical outcomes in this setting.
SCIENTIFIC REPORTS
(2021)
Article
Physiology
Jiarui Cui, Yo Shibata, Keiji Itaka, Jun Zhou, Jiaming Zhang
Summary: This study used bioinformatic analyses to identify the impact of exercise on cartilage transcriptome, revealing that exercise suppressed genes related to various cellular functions and inflammatory responses, with downregulated genes being more stable over time. Additionally, the study identified time-related signaling pathways and clusters of genes responsive to exercise duration, advancing the understanding of cartilage homeostasis.
FRONTIERS IN PHYSIOLOGY
(2022)
Review
Biology
Vanessa Silva Caiado, Aline Cristina Gomes Santos, Eloa Moreira-Marconi, Marcia Cristina Moura-Fernandes, Aderito Seixas, Redha Taiar, Ana Cristina Rodrigues Lacerda, Anelise Sonza, Vanessa Amaral Mendonca, Danubia Cunha Sa-Caputo, Mario Bernardo-Filho
Summary: This study examined the effects of physical exercise alone, without an associated diet plan, on individuals with both obesity and knee osteoarthritis (KOA). Through a summary of 10 studies, it was found that physical exercise performed alone seems to improve the functional capacity of these individuals, even without an associated diet plan.
Article
Sport Sciences
Z. Kairiukstiene, K. Poderiene, D. Velicka, E. Trinkunas, J. Poderys
Summary: The study compared the effects of aerobic + interval exercise and aerobic exercise on the cardiovascular functional state in females and found significant ECG changes in some participants after the AI session, indicating atypical physiological responses to high-intensity workouts.
Article
Physiology
J. Alberto Neder, Devin B. Phillips, Mathieu Marillier, Anne-Catherine Bernard, Danilo C. Berton, Denis E. O'Donnell
Summary: Interpretation of CPET has limitations that should be recognized, with a focus on identifying dysfunction based on variable clusters, avoiding prolixity and redundancy in graphical data display, and understanding the relationship between submaximal dyspnea ratings, work rate and ventilatory demand. Additionally, measuring dynamic inspiratory capacity is crucial in uncovering abnormalities related to exertional dyspnea.
FRONTIERS IN PHYSIOLOGY
(2021)
Review
Health Care Sciences & Services
Damian Fernandez-Costa, Juan Gomez-Salgado, Andres Castillejo del Rio, Alvaro Borrallo-Riego, Maria Dolores Guerra-Martin
Summary: This study aimed to evaluate the effectiveness of prehabilitation on functional capacity and physiological reserve in aged patients undergoing cardiothoracic surgeries. The results suggest that prehabilitation may improve patients' functional capacity and postoperative recovery.
Review
Oncology
Sarah M. Belcher, Emilie A. Hausmann, Susan M. Cohen, Heidi S. Donovan, Elizabeth A. Schlenk
Article
Nursing
Chun-Ja Kim, JeeWon Park, Se-Won Kang, Elizabeth A. Schlenk
INTERNATIONAL JOURNAL OF NURSING PRACTICE
(2017)
Article
Rheumatology
Benjamin J. Smith, Marcy B. Bolster, Barbara Slusher, Christine Stamatos, Jeanne R. Scott, Heather Benham, Salahuddin Kazi, Elizabeth A. Schlenk, Daniel E. Schaffer, Vikas Majithia, Calvin R. Brown, Joan M. Von Feldt, Joseph Flood, David M. Haag, Karen L. Smarr
ARTHRITIS CARE & RESEARCH
(2018)
Article
Computer Science, Interdisciplinary Applications
Wei-Chun Lin, Lora Burke, Elizabeth A. Schlenk, Chao Hsing Yeh
CIN-COMPUTERS INFORMATICS NURSING
(2019)
Letter
Rheumatology
Benjamin J. Smith, Marcy B. Bolster, Barbara Slusher, Christine Stamatos, Jeanne R. Scott, Heather Benham, Salahuddin Kazi, Elizabeth A. Schlenk, Daniel E. Schaffer, Vikas Majithia, Calvin R. Brown, Joan M. Von Feldt, Joseph Flood, David M. Haag, Karen L. Smarr
ARTHRITIS CARE & RESEARCH
(2019)
Article
Nursing
Chun-Ja Kim, Hyung-Ran Park, Elizabeth A. Schlenk, Se-Won Kang, Eun Ji Seo
ARCHIVES OF PSYCHIATRIC NURSING
(2019)
Article
Medicine, Research & Experimental
Chao Hsing Yeh, Cuicui Li, Ronald Glick, Elizabeth A. Schlenk, Kathryn Albers, Lorna Kwai-Ping Suen, Nada Lukkahatai, Nicole Salen, Sonaali Pandiri, Weixia Ma, Nancy Perrin, Natalia E. Morone, Paul J. Christo
Article
Nursing
Chun-Ja Kim, Hee Sun Kang, Jung Suk Kim, Ye Yeon Won, Elizabeth A. Schlenk
Article
Geriatrics & Gerontology
Elizabeth A. Schlenk, Susan M. Sereika, Lynn M. Martire, Xiaojun Shi
Summary: The study aimed to explore the social networks and support of older adults during a physical activity intervention, and how it is associated with physical activity. Findings showed that receiving support for physical activity from a spouse/partner, adult child, or friend led to greater improvements in daily physical activity minutes. Participants also developed plans to receive support from their close relationships for physical activity.
Review
Nursing
Chun-Ja Kim, Moonsun Kim, Ga-Young Lee, Eunyoung Park, Elizabeth A. Schlenk
Summary: This study aimed to evaluate the effectiveness of nurse-led interventions on medication adherence, medication knowledge, and clinical outcomes in adults with metabolic syndrome. The findings showed that nurse-led interventions had a moderate impact on enhancing medication adherence and knowledge and improving clinical outcomes. Factors such as intervention duration, delivery mode, and use of multiple strategies influenced the effectiveness of nurse-led medication adherence interventions.
JOURNAL OF CLINICAL NURSING
(2023)
Review
Nursing
Seol Ju Esther Moon, Elizabeth A. Schlenk, Heeyoung Lee
Summary: Heart rate variability (HRV) is an indicator of autonomic abnormalities, but its role in substance use behavior and association with relapse signs is not well understood. This study aimed to review existing literature on HRV in substance users and its outcomes related to relapse risk factors. A systematic search of literature published in English from 2010 to 2020 was conducted, and 14 studies were included. The findings suggest that substance users have significantly decreased resting HRV compared to healthy controls, and lower HRV is associated with stress, craving, and greater symptom severities in individuals with substance use disorders. HRV may serve as a useful tool for monitoring relapse indications and guiding relapse prevention strategies.
JOURNAL OF THE AMERICAN PSYCHIATRIC NURSES ASSOCIATION
(2023)
Article
Nursing
Chun-Ja Kim, Hye-Won Yun, Hee Sun Kang, Ju-Yang Jung, Elizabeth A. Schlenk
Summary: This study aimed to examine a hypothetical model of physical activity (PA) and health outcomes related to sarcopenia in women with rheumatoid arthritis (RA) based on self-determination theory. A cross-sectional study was conducted with 214 women diagnosed with RA from a university-affiliated hospital in South Korea. The results showed that physical activity was directly influenced by motivation for PA, while factors such as depression, self-efficacy for PA, health care provider's autonomy support, and basic psychological needs satisfaction indirectly affected PA. Physical activity directly affected perceived health status and thigh circumference, while perceived sarcopenia risk and handgrip strength were directly affected by disease activity and age.
Article
Endocrinology & Metabolism
Moonsun Kim, Chun-Ja Kim, Dae Jung Kim, Elizabeth A. Schlenk
Summary: This study translated the Perceived Therapeutic Efficacy Scale (PTES) into Korean and validated its effectiveness and reliability among patients with type 2 diabetes in Korea. Results showed significant associations between PTES-K scores and diabetes self-care activities, quality of life, and depressive symptoms in participants.
SCIENCE OF DIABETES SELF-MANAGEMENT AND CARE
(2022)
Article
Health Policy & Services
Janice C. Zgibor, Lei Ye, Robert M. Boudreau, Molly B. Conroy, Joni Vander Bilt, Elizabeth A. Rodgers, Elizabeth A. Schlenk, Mini E. Jacob, Jane Brandenstein, Steven M. Albert, Anne B. Newman
JOURNAL OF COMMUNITY HEALTH
(2017)
Article
Public, Environmental & Occupational Health
Janice C. Zgibor, Elizabeth A. Schlenk, Laura Vater, Sushma Kola, Joni Vander Bilt, Sarah Woody, Mini E. Jacob, Wei-Hsuan Lo-Ciganic, Allison Brenckle, Jane Brandenstein, C. Kent Kwoh, Robert Boudreau, Steven Albert, Margaret Conroy, Elizabeth Rodgers, Anne B. Newman
PROGRESS IN COMMUNITY HEALTH PARTNERSHIPS-RESEARCH EDUCATION AND ACTION
(2016)