Editorial Material
Radiology, Nuclear Medicine & Medical Imaging
Chenxi Wu, Lance T. Hall, David C. Brandon
Summary: An 82-year-old man underwent outpatient nuclear medicine gastric-emptying scintigraphy for dysphagia and regurgitation. The scintigraphy showed delayed gastric emptying but subsequent CT scan and upper gastrointestinal fluoroscopy revealed normal stomach size and function, with an enormously dilated esophagus indicating achalasia. It is important to pay attention to the location and shape of the visualized stomach and recognize that a significantly dilated esophagus can mimic an elongated stomach during scintigraphy.
CLINICAL NUCLEAR MEDICINE
(2022)
Review
Medicine, General & Internal
Raj K. Goyal
Summary: Research shows that gastric emptying abnormalities in diabetes can lead to postprandial dyspepsia and impaired plasma glucose regulation. Treatment should address whether the emptying is delayed or rapid.
NEW ENGLAND JOURNAL OF MEDICINE
(2021)
Article
Endocrinology & Metabolism
Simon Veedfald, Jens F. Rehfeld, Gerrit van Hall, Lars B. Svendsen, Jens J. Holst
Summary: The study investigated the rapid entero-pancreatic hormone secretion after nutrient ingestion and its correlation with gastric emptying and glucose absorption. Findings showed characteristic differences in timing and amplitude of early postprandial hormone responses, emphasizing the need to consider individual variations when interpreting mean responses and designing study protocols.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
(2022)
Article
Gastroenterology & Hepatology
Lai Wei, Rajan Singh, Se Eun Ha, Alyce M. Martin, Lauren A. Jones, Byungchang Jin, Brian G. Jorgensen, Hannah Zogg, Tyler Chervo, Andres Gottfried-Blackmore, Linda Nguyen, Aida Habtezion, Nick J. Spencer, Damien J. Keating, Kenton M. Sanders, Seungil Ro
Summary: The study utilized a transgenic mouse line specific to EC cells to investigate the pathophysiologic roles of 5-HT deficiency in gastric motility. Findings indicated a new mechanism of 5-HT deficiency in idiopathic gastroparesis.
Article
Surgery
Sven E. Eriksson, Ping Zheng, Inanc S. Sarici, Xinxin Shen, Blair A. Jobe, Shahin Ayazi
Summary: This study investigates the relationship between delayed gastric emptying (DGE) and outcomes of magnetic sphincter augmentation (MSA) surgery. It found that mild-to-moderate DGE diminishes surgical outcomes in the short term, but by 1 year, outcomes become comparable and remain stable at 2 years. Severe DGE may result in suboptimal surgical outcomes.
SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES
(2023)
Review
Food Science & Technology
Weilin Liu, Yangyi Jin, Peter J. Wilde, Yingying Hou, Yanping Wang, Jianzhong Han
Summary: Gastric emptying is a crucial process where the stomach releases its contents into the small intestine for further digestion and absorption, with factors such as calories, viscosity, food composition, age and gender playing important roles. In vitro digestion models are essential for studying gastric emptying when in vivo tests are not feasible, and progress in static and dynamic gastric digestion models are highlighted in this review to explore future research trends.
CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION
(2021)
Review
Food Science & Technology
Yangyi Jin, Peter J. Wilde, Yingying Hou, Yanping Wang, Jianzhong Han, Weilin Liu
Summary: This article reviews the factors influencing food viscosity and changes in food viscosity during digestion. It also examines the effects of food viscosity on gastric emptying and physiological responses. Additionally, the quantitative relationship between viscosity and gastric emptying is discussed.
CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION
(2023)
Article
Multidisciplinary Sciences
Shih-Hao Mao, Bor-Shiuan Shyr, Shih-Chin Chen, Shin-E Wang, Yi-Ming Shyr, Bor-Uei Shyr
Summary: The study found that robotic pancreaticouodenectomy (RPD) had a lower incidence of delayed gastric emptying (DGE) compared to open pancreaticouodenectomy (OPD). Nausea/vomiting, jaundice, malignancy, and lymph node involvement were identified as significant risk factors for DGE. Intraoperative blood loss and postoperative complications were not significantly associated with DGE, but the hospital stay was longer in patients with DGE.
SCIENTIFIC REPORTS
(2022)
Article
Oncology
Marco Baia, Lorenzo Conti, Sandro Pasquali, Catherine Sarre-Lazcano, Carlo Abatini, Stefano Piero Bernardo Cioffi, Serena Della Valle, Giorgio Greco, Raffaella Vigorito, Amanda Casirati, Paolo Proto, Cecilia Gavazzi, Alessandro Gronchi, Marco Fiore
Summary: This study analyzed cases of 100 patients with primary retroperitoneal sarcoma and found that delayed gastric emptying (DGE) is a common complication, especially after multivisceral resection. DGE is associated with prolonged hospital stay, ICU admission, and other complications. Patient comorbidities and tumor size are independent risk factors for DGE.
ANNALS OF SURGICAL ONCOLOGY
(2022)
Article
Gastroenterology & Hepatology
Ted Xiao, Kenneth Koch, Brent Bones, Jean-Luc Claude Urbain, Paige Bennett, Jared Rejeski
Summary: Idiopathic rapid gastric emptying (RGE) is an important differential diagnosis in patients with symptoms classically associated with gastroparesis. The majority of patients with idiopathic RGE present with symptoms such as nausea, vomiting, and abdominal pain. Further research on idiopathic RGE syndrome is warranted.
JOURNAL OF DIGESTIVE DISEASES
(2021)
Article
Gastroenterology & Hepatology
Zarife N. Ozdemir-Kumral, Turkan Koyuncuoglu, Sevil Arabaci-Tamer, Ozlem T. Cilingir-Kaya, Ayca K. Koroglu, Meral Yuksel, Berrak C. Yegen
Summary: High-fat diet induced mild systemic inflammation, disrupted enteric innervation, enhanced gastric contractility, inhibited ileal contractility, and eliminated the inhibitory effect of NES-1 on gastric motility.
JOURNAL OF NEUROGASTROENTEROLOGY AND MOTILITY
(2021)
Article
Multidisciplinary Sciences
Tomosuke Mukoyama, Shingo Kanaji, Ryuichiro Sawada, Hitoshi Harada, Naoki Urakawa, Hironobu Goto, Hiroshi Hasegawa, Kimihiro Yamashita, Takeru Matsuda, Taro Oshikiri, Yoshihiro Kakeji
Summary: This study aimed to investigate the risk factors and severity of delayed gastric emptying (DGE) after gastrectomy. Female sex, diabetes, and distal gastric tumors were identified as independent risk factors for DGE. The DGE group had a longer hospital stay compared to the non-DGE group, and most DGE cases occurred after 1 week following surgery.
SCIENTIFIC REPORTS
(2022)
Article
Endocrinology & Metabolism
Cong Xie, Weikun Huang, Linda E. Watson, Stijn Soenen, Richard L. Young, Karen L. Jones, Michael Horowitz, Christopher K. Rayner, Tongzhi Wu
Summary: The study found that gastric emptying is not a determinant of the postprandial GLP-1 response in individuals, but the intrinsic gastric emptying rate is partly determined by the responsiveness of GLP-1 to intestinal nutrients.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
(2022)
Article
Gastroenterology & Hepatology
Xiao Jing Wang, Duane D. Burton, Margaret Breen-Lyles, Michael Camilleri
Summary: This study found that postprandial gastric accommodation is significantly associated with the rate of gastric emptying, with higher gastric volumes leading to prolongation of emptying. The study also introduced novel methods to measure proximal gastric accommodation and correct for radioisotope upscatter.
AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY
(2021)
Article
Cell Biology
Haifeng Qin, Shushu Zhang, Linling Shen, Chenjian Mao, Guangyu Gao, Hui Wang
Summary: This study found that PRSS2 may play important roles in the carcinogenesis and progression of gastric cancer (GC) and can be potential biomarkers for patients with GC.
